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Early Predictive Factors for Scleroderma Renal Crisis

d Jack Cush, MD

It has been historically said that risk factors for scleroderma renal crisis (SRC) includes include cold exposure, steroid use, dehydration, rapid progression of skin disease, tendon friction rubs, anti-RNA polymerase III antibodies and pregnancy.  A new study examines risk factor for S

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Diet and Weight Loss Improves Psoriatic Arthritis

d Jack Cush, MD

Short-term intervention with the very low energy diet (VLED) in psoriatic arthritis (PsA) with obesity (body mass index BMI ≥ 33 kg/m2) showed that weight loss was associated with significant positive benefits on weight and disease activity in joints, entheses and skin. 

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Only One-Third of Gout Patients Receive Urate-Lowering Drugs

d Jack Cush, MD

The most recent analysis of National Health and Nutrition Examination Survey [NHANES] 2007-2016) data shows the prevalence of gout to be 9.3 million in the USA.

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RheumNow Podcast – Gout Spot Light (1.11.19)

d Jack Cush, MD

Dr. Jack Cush discusses the highlights from the past week on RheumNow.com:

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Heberden’s Nodes Predict Knee OA Progression

d Jack Cush, MD

Hand and knee osteoarthritis are considered to be clinically and pathogenically different and distinct, but a new study suggests that Heberden's nodes (HNs) can predict MRI‐based knee osteoarthritis (OA) progression.

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NEJM Review - Glucocorticoid-Induced Osteoporosis

d Jack Cush, MD

Lenore Buckley and Mary Humphrey have published a nice review of glucocorticoid-induced osteoporosis (GIOP) in the NEJM.

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National registry of lupus nephritis pts w/ ESRD (n=20,974) between 1995-2014 showed that mortality declined from 11.1 to 6.7/100PY; Mortality declined for whites (HR 0.68), blacks (0.67) and Hispanics (0.51) and declined for CVD and infx by 44% & 63% https://t.co/0zDQmLymes

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Dr. John Cush RheumNow ( View Tweet)

Combined study of Danbio (Denmark) and ARTIS (Sweden) RA registries showed that in 8987 treatment courses of abatacept, rituximab or tocilizumab there was no difference in Serious infection rates - ranging from 4.7-8.1 SIE/100 Pt Yrs. https://t.co/JpYDeSPdpy

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Dr. John Cush RheumNow ( View Tweet)

CDC report 5 Jan 2019: 7 million cases of influenza w/ an estimated 69,000 to 84,000 hospitalized for flu-related illness. H1N1 is the most common strain. Flu activity is widespread in 30 states https://t.co/kLsZjKDJen

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Dr. John Cush RheumNow ( View Tweet)

Rheumatology Year in Review : New Drugs, irAEs, Enbrel in court, Opioids, new JAKs, Hot PsA Trial, new Lupus drugs, Medical Marijuana, Expen$ive Rheum drugs, Senolytics. https://t.co/9VpM4yRGfY

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Dr. John Cush RheumNow ( View Tweet)

QD Video on RheumNow - an HLA-B27+ patient with Iritis, Enthesitis, Diarrhea. https://t.co/LusZttdAyw

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Dr. John Cush RheumNow ( View Tweet)

QD Video from RheumNow - The RA patients with Thrombocytopenia https://t.co/GHn6b6Z3kb

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Dr. John Cush RheumNow ( View Tweet)

RheumNow Podcast is up - discussing Gout FDA hearing, Gout Prevalence, ULT use, obesity, BMS-Celgene merger and more. Watch here https://t.co/J5xdqGYWAu Listen on iTunes or here> https://t.co/qHAO4E9cfX

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Dr. John Cush RheumNow ( View Tweet)

FDA AAC + DSRM advisory committee votes 19 yes, 2 no and 1 abstain on continued use of Uloric/febuxostat after reviewing CV risk in the CARES study. Await FDA decision, but Look for label changes.

Dr. John Cush RheumNow ( View Tweet)

QD Video - lessons from the Clinic - How to evaluate the Takayasu's arteritis patient. https://t.co/tZcOOKlcVU

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Dr. John Cush RheumNow ( View Tweet)

“The road to hell is paved with biologic plausibility”. - Dr. Steve Nissan

Dr. John Cush RheumNow ( View Tweet)

Today - anuary 11, 2019: Joint Meeting of the Arthritis Advisory Committee and the Drug Safety and Risk Management Advisory Committee Meeting to discuss Safety of Febuxostat v Allopurinol. No webcast. Here are briefing documents https://t.co/DXo3EX8u9y

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Dr. John Cush RheumNow ( View Tweet)

Tuhina Neogi, MD, PhD, professor of medicine, has been named chief of the section of rheumatology, in the department of medicine at BU School of Medicine (BUSM) and Boston Medical Center (BMC). https://t.co/0HUj0ji40o

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Dr. John Cush RheumNow ( View Tweet)

FDA has approved a single-injection hyaluronic acid (Durolane – Bioventus) and an ER formulation of the synthetic corticosteroid triamcinolone acetonide (Zilretta – Flexion) for intra-articular (IA) treatment of osteoarthritic knee pain. https://t.co/7rgsflNMVq

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Dr. John Cush RheumNow ( View Tweet)

Cluster analysis of 157 SAPHO pts shows 3 distinct patterns or types - spinal type (44.6%; spinal, sacral); costal type (33.1%; ribs) and sternoclavicular type (22.3%) disease course was longer in SC type than costal or spinal types (P < 0.001). https://t.co/NI7AylAoZt

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