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@_connectedcare @RheumNow @ACRheum My pearls (so far)
1. Use vitamin A to reduce SEs w MTX
2. Try doxycycline for refractory calcinosis in scleroderma
3. Use MTX with pegloticase to reduce infusion reactions
4. Anti-IL17 has activity in nr-axSpA
5. Patients think opiates are more effective than SNRIs or TCAs in FM
Philip Robinson philipcrobinson ( View Tweet)
@RheumNow #ACR19 #acrbest abs2470 ⬆️serum calprotectin in PsA pts associated w/presence of carotid plaque, ⬆️intima-media thickness & ⬆️CRP. potential novel bio marker of CV disease in PsA https://t.co/ech3Ll8Nka
Olga Petryna DrPetryna ( View Tweet)
As I leave #acr19, time to reflect. My goal is to uncover pearls that change what I do in my next few clinics. 3 this time. How many such pearls did you find? @RheumNow @ACRheum
Dr Irwin Lim _connectedcare ( View Tweet)
@rheumnow #ACR19 abs2854 internationPsART cohort data: age of onset defines if PSO or PSA starts first (PSO precedes in younger pts), Pustular PSO associated w/shorter time interval PSO to arthritis while nail involvement, plaque PSO & PSO family Hx associated w/ longer interval https://t.co/KtPXhYdbky
Olga Petryna DrPetryna ( View Tweet)
Do you still look at synovial fluid under the microscope? @rheumnow #acr19
k dao KDAO2011 ( View Tweet)
Baricitinib additional improvement in pain vs ADA despite accounting for effect on disease activity https://t.co/zAjS2dOayF @RheumNow
Dr. Arthur Lau ArthurRheum ( View Tweet)
Claims data showing switching from ETN or ADA to Tofa had higher drug survival vs cycling to another TNF. Does not provide reason for discontinuation though https://t.co/yTNHkKanJA @RheumNow #ACR19
Dr. Arthur Lau ArthurRheum ( View Tweet)
Weight loss in IgG4-RD NOT because of overwhelming systemic inflammation but from pancreatic involvement. Need pancreatic enzyme replacement. #ACR19 @RheumNow
Maeve Gamble MaeveGamble ( View Tweet)
Abstr#2729: 303 pts randomized. More pts achieved ASAS40 at Wk 16: IXE Q2W (40%), IXE Q4W (35%) vs PBO (19%, p< 0.01) and at Wk 52: IXE Q2W (31%), IXE Q4W (30%) vs PBO (13%, p< 0.01). Blocking IL-17A is a potential treatment option for patients with nr-axSpA. #ACR19 @RheumNow
Maeve Gamble MaeveGamble ( View Tweet)
Fantastic view of how specific defects in the immune system lead to various clinical presentations and laboratory abnormalities. Dr. Mahta Mortezavi #ACR19 @RheumNow https://t.co/ht7VBhDdpR
Jonathan Hausmann MD hausmannMD ( View Tweet)
Drs. Davila and Solow say “No good data to suggest that biologic DMARDs contribute to progression of MGUS so okay to treat as you normally would.” #ACR19 @RheumNow https://t.co/5r2W4q1t5c
Dr. Rachel Tate uptoTate ( View Tweet)
While immunoglobulin replacement for patients with CVID prevents infections, it does not correct any of the autoimmune features....keeping rheumatologists busy! Dr. Mahta Mortezavi #ACR19 @RheumNow
Jonathan Hausmann MD hausmannMD ( View Tweet)
#acr19 @RheumNow
Dr West’s Pearls:
- at 40x magnification of synovial fluid, 1 WBC per hpf = 500 WBC/ uL (hence, 5 WBCs seen= 2500 WBC/uL which means the pt has an inflammatory fluid - you don’t have to wait for the lab results!) https://t.co/nChSnFq5NL
k dao KDAO2011 ( View Tweet)
The updated ACR/NPF treatment recommendations for PsA were discussed by Dr. Mease and Dr. E. Husni at #ACR19. Will you start with a TNFi, as per these recommendations, over other medications for your tx naive patients? @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)
Nice work showing PROs correlate with high disease activity in pts w/checkpoint inhibitor-related inflammatory arthritis abstr#2151 @cappelliMD @LCalabreseDO @RheumNow #ACR19 #cleclinicrheum https://t.co/Yi8LhNhA0v
Cassandra Calabrese CCalabreseDO ( View Tweet)
500 patients with CVID
-94% had infections
-30% had autoimmunity
-30% had chronic lung disease
-10% had granulomatous disease
-Dr. Mahta Mortezavi
Need I convince you any further to consider CVID when evaluating your patients with rheumatic disease?
#ACR19 @RheumNow
Jonathan Hausmann MD hausmannMD ( View Tweet)
#ACR19 poll: Do you use Prednisone to manage symptoms of hand osteoarthritis? @RheumNow
Dr. Paul Sufka psufka ( View Tweet)
Nice job @didemsayginmd ! Abstr#2144 single center rheumatic irAE experience - 50% required ICI interruption! 20% needed DMARDs @RheumNow #ACR19 #cleclinicrheum https://t.co/dGaIaKzYFS
Cassandra Calabrese CCalabreseDO ( View Tweet)
@rheumnow #ACR19 ABS2594 prospective cohort study of 56 early cutaneous SSc pts found no association between ETAR &AT1R Abs positivity & vascular complications making ETAR &AT1R abs unlikely prognostic markers of Vasc complications #acrbest https://t.co/e9kNSFeBOx
Olga Petryna DrPetryna ( View Tweet)
Some immunodeficiencies present primarily with autoimmune or lymphoproliferative features…hence the need to consider immunodeficiency in patients with suspected rheumatic disease. Dr. Mahta Mortezavi #ACR19 @RheumNow
Jonathan Hausmann MD hausmannMD ( View Tweet)
