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#myositis & the ❤: lab tests ⬆ Trop = myocardial stress & injury, absence doesn't r/o myocarditis BNP - utility unclear There are no biomarkers specific for myocardial involvement @RheumNow #ACR20 https://t.co/eyihKPoXSc
sheila RHEUMarampa ( View Tweet)
ACR20 Podcast

QD Clinic Podcast - 106 thru 109

d Jack Cush, MD

Here is the last of our QD Clinics in Podcast form, just before we start ACR2020 coverage.



In this compilation from the past week we talk about



- HIV and arthritis



- Hyperuricemia in PsA



- An odd kind of dermatomyositis

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RheumNow Podcast – ACR 20 is Coming to Town (10.30.20)

d Jack Cush, MD

Dr Jack Cush overviews the RheumNow commitment, upcoming bonus coverage of ACR20 and the good news and journal reports from the past week on RheumNow.com

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Muscle (keep)

Immune Necrotizing Myopathy

d Jack Cush, MD

A full read review of immune-mediated necrotizing myopathy is portrayed as a distinct subtype of inflammatory myopathies first described in 2004.

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Study from China finds that hemophagocytic lymphohistiocytosis (HLH) was a rare (4.2%) but fatal (77.8%) complication in myositis patients (DM, PM, or CADM). Risk factors include baseline Dz activity, worsening ILD and infection https://t.co/QDN1DYzl5p

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Dr. John Cush RheumNow ( View Tweet)

Among a 112 patient inflammatory myositis cohort, inclusion body myositis was rare (4 pts) - they tend to be older (67 yrs), male predominance, lower CK (1326-1968), less severe weakness 3.75/5) and poor response to immunosuppressives. https://t.co/VxLOAjstWo

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Dr. John Cush RheumNow ( View Tweet)

ILD studied in 679 inflammatory idiopathic myositis (IIM) pts; 508 had ILD (found in 93% amyopathic DM, 74% DM & 55% PM). Prevalence of of ILD was higher with antisynthetase Ab + and MDA-5 Ab +. Mortality higher in MDA5+ASA--IM-ILD group (33% vs 12=17%) https://t.co/ATz3wYmFuf

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Dr. John Cush RheumNow ( View Tweet)

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RheumNow Podcast – Rheum Lives Matter (8.28.20)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from the past week. Of mice and men in cartilage, the efficacy of JAK inhibitors in patients who are having skin problems, nrAxSpa has its own diagnostic code, metformin, talking about Back Talk, plus so much more.

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Hong Kong study Myositis-specific autoantibodies in 201 pts with idiopathic inflammatory myopathies (IIM) shows MDA-5 (14%), TIFF-1γ (14%), Jo-(12.4%). MDA5 seen w/ DM, digital ulcers, amyopathy, ILD. TIF1γ was associ w/ refractory rash and cancer https://t.co/3E365F5SON

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Dr. John Cush RheumNow ( View Tweet)

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RheumNow Podcast - Top 13 Rheumatology Centers (7-31-20)

d Jack Cush, MD

Dr. Jack Cush reviews the news and TOP 13 list of Best Rheumatology Hospitals.

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Fracture risk & prevalence of osteoporosis is elevated in patients with idiopathic inflammatory myopathies: cross-sectional comparison of 52 myositis and 43 RA pts. OP Prevalence higher in the myositis group (13.5% v 7%) but equal fracture risk (68 v 75%) https://t.co/XT6O9HoqdH

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Dr. John Cush RheumNow ( View Tweet)

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RheumNow Podcast – COVID-19 Responds to Steroids (7.24.20)

d Jack Cush, MD

Dr. Jack Cush reviews the News and Journal Reports from the past week on RheumNow.com.

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FINAL 2020 Podcast Graphic

RheumNow Podcast – LTF – Listen to Fauci (7.17.20)

d Jack Cush, MD

Dr. Jack Cush reviews the news, tweets and journal articles from the past week on RheumNow. Let's dig into this week's 14 highlights.

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RheumNow Podcast is Up! Listen to Fauci! Watch it here>> https://t.co/dHq3fP85Ip or Listen to the Podcast>> https://t.co/LdHO7fKUCp

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Dr. John Cush RheumNow ( View Tweet)

RheumNow Podcast is Up! Listen to Fauci! Watch it here>> https://t.co/dHq3fP85Ip or Listen to the Podcast>> https://t.co/LdHO7fKUCp

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Dr. John Cush RheumNow ( View Tweet)

Retrospective study of 603 myositis (IIM), 4047 RA and 4061 controls shows IIM has higher risk of CV events (HR 1.38) and MI [HR 1.61] but not CVA [HR 0.92]. The CV risk in IIM was equal to that in RA [HR 1.01]. IIM CV risk only present 1st 5 years https://t.co/EyD3GHv2YY

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Dr. John Cush RheumNow ( View Tweet)

Systematic review of DYSPHAGIA in inflammatory myositis finds it may be an initial or sole symptom. Prevalence in IIM was 36% and higher 56% inclusion body myositis, cancer or NXP2 -associated myositis. Dysphagia may be complicated by aspiration pneumonia https://t.co/wDg3tWaooP

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Dr. John Cush RheumNow ( View Tweet)

heart.EKG_.CVD_.jpg

CV Risks Raised in Myopathies

d Jack Cush, MD

Patients with the idiopathic inflammatory myopathies (IIMs) dermatomyositis and polymyositis are at increased risk for cardiovascular events, with risks similar to what has been documented for rheumatoid arthritis (RA), during the first 5 years after diagnosis, U.K. researchers reported.

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#EULAR2020 #op0169 US claims database analysis reveals that gout and DM make for a dangerous combination: significantly higher risk of amputations in pts with gout+DM at 0.77% as oppose to DM w/out gout 0.461% & gout w/out DM 0.162% @RheumNow

Olga Petryna DrPetryna ( View Tweet)

#EULAR2020 Recc for irAEs w/ICI: 1. GC's ok, goal<10 mg/d, any csDMARD, bDMARD (TNFi/IL-6),🚫ABT xcept life-threatening myositis 2. Myositis beware bulbar signs: dysphagia, dysarthria, dysphonia: stop ICIs,⬆️GC, IVIG/PE 3. Don't test autoAbs b/f ICI Rx https://t.co/P5jDgnjK94

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k dao KDAO2011 ( View Tweet)

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