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NK cells and a Potential Role in the Development of PsA vs PsC (Cutaneous Psoriasis)
Human NK cells express multiple receptors that interact with HLA class I molecules which, in turn, suppy peptides that bind HLA-E to form CD94/NKG2A NK receptor ligands.
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What is the Future of MTX for Psoriatic Arthritis?
Like most rheumatologists, I retain a deep and abiding love for methotrexate.
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Autoimmunity in the Setting of Primary Immunodeficiency
There are many avenues for interdisciplinary collaboration within rheumatology, as our specialty encompasses every organ system and diseases with protean manifestations.
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European cohort study shows RA and SpA patients switched from Enbrel to SB4 had similar DAS28 and BASDAI respectively at 3 mth f/u @RheumNow #ACR18 https://t.co/lWpBsEeC7k
Arthur Lau ArthurRheum ( View Tweet)
Dr. Apostolos Konzis, adaptive immune response in idiopathic pericarditis: 67% presence of anti heart antibodies against myosin and anit-intercalcated antibodies with no identifiable self antigen #Acr18 @RheumNow
Suleman Bhana, MD DrBhana ( View Tweet)
Family planning in Rheumatology: ASK about pregnancy intent & contraception often. Give facts and resources regarding these issues. So important to improve outcomes in both women and future children. #ACR18 @RheumNow
Brittany A MissbeeMD ( View Tweet)
RheumNow expanded twitter coverage of the ACR 2018 Annual meeting sponsored in part by Horizon Pharma. All content chosen and distributed by RheumNow and its faculty.
Dr. John Cush RheumNow ( View Tweet)
Dr Polly Ferguson's advice: look elsewhere when something is unusual in infectious osteomyelitis especially chest- first rib is often involved in #SAPHO #CRMO #ACR18 @RheumNow
Nicole Bitencourt NicoleBitencou5 ( View Tweet)
Dr. Ferguson. C(P).Acnes bacteria may be a trigger for SAPHO syndrome via activation of the NLRP3 inflammasome #ACR18 @RheumNow
https://t.co/BGHP18Ue5Y
Suleman Bhana, MD DrBhana ( View Tweet)
#ACR18 Late Breaking:
#L15 Anthony Sammel - PET/CT vs TAB for suspected GCA. PET 92% sens, 85% spec. (NB 3/7 false+ were clinically diagnosed with GCA). NPV 98%. Kappa 0.65. Including 4 vessels improves PET performance.
Great data, GCA Dx remains a difficult art.
@RheumNow https://t.co/eAA3QNYBfd
ǝlʇʇıɥʍ ɯɐs samwhittle ( View Tweet)
RheumNow expanded twitter coverage of the ACR 2018 Annual meeting sponsored in part by Eli Lilly and Company. All content chosen and distributed by RheumNow and its faculty.
Dr. John Cush RheumNow ( View Tweet)
Men on SSZ: do not discontinue proper to conception... but can have effects on sperm count/motility/morphology so consider sperm analysis if difficulty conceiving while on SSZ.
#ACR18 @RheumNow
Brittany A MissbeeMD ( View Tweet)
Dr Eric Matteson - Philip Hench Lecturer #acr18 The best Disclosure slide ever! “I prescribed a lot of C21H28O5” (that’s Cortisone to you and me) ! In fact, we all still do. 2.5 million Americans take steroids on any given day. @rheumnow Has it had it’s day? https://t.co/7Cw2IDtfyZ
Philip Gardiner PhilipGardiner ( View Tweet)
#ACR18 @RheumNow abs 2836 maybe it's time to think across connective tissue diseases as well as within them to better understand their molecular taxonomy. A bit of shameless self-promotion!! @Dr_JohnR @tracyannbriggs https://t.co/CL6vH0zbDj
Ian N Bruce Lupusdoc ( View Tweet)
CPT II carnitine palmitoyltransferase 2 defect presents with #recurrent #rhabdomyolisis with exertion. Send plasma acylcarnitine profile in acute phase. #GeneticMimicsOfRheumaticDisease #ACR18 @RheumNow
Nicole Bitencourt NicoleBitencou5 ( View Tweet)
Enbrel non medical switch study w 89 pts switching. No sig change in DAS28-ESR, SJC/TJC/global scores but only 3 month f/u... data on Enbrel non med switches have been very sparse so every study, even small is important right now @RheumNow #ACR18 https://t.co/DouMLWlIix
Arthur Lau ArthurRheum ( View Tweet)
Patients and HCPs main concerns re: biosimilars are less efficacy and being forced to switch @RheumNow #ACR18 https://t.co/wDBpxzpPE5
Arthur Lau ArthurRheum ( View Tweet)
#ACR18 Neil Basu from Aberdeen showing some lovely functional brain imaging data that implies that #fibromyalgia symptoms in RA have similar neurobiological signature to ‘primary’ FM. Strong correlation between FM survey score and DMN-insula connectivity.
@RheumNow https://t.co/onrbeLhOYM
ǝlʇʇıɥʍ ɯɐs samwhittle ( View Tweet)
Based on this survey, most MDs don’t agree with biosimilar interchangeability, but most pharmacist think it’s ok @RheumNow #ACR18 https://t.co/ZhM2h3AD2b
Arthur Lau ArthurRheum ( View Tweet)
#ACR18 @rheumnow abs 2419. In a busy clinic, ask 'one key question' as a way to opening discussion on pregnancy planning in SLE. With an EPR it can even come up as a prompt on your screen. https://t.co/hQwlcxIZrB
Ian N Bruce Lupusdoc ( View Tweet)