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#ClinicalPearls #rheumatoid #arthritis is changing. Less extra articulation and less mortality except ILD. Legacy pts exposed to ASA high dose, NSAIDs and injectable gold. We still see it rarely. @RheumNow #EULAR2023 @eular_org https://t.co/sC8vZkjO2x https://t.co/BFdpubei4u
Janet Pope Janetbirdope ( View Tweet)
Debate @ #EULAR2023 @eular_org about clinically suspect arthralgia. Myth or just #rheumatoid #arthritis in the making? https://t.co/Kj4CeE3NtU
Janet Pope Janetbirdope ( View Tweet)
Did you know?
Painter Peter Paul Rubens had Rheumatoid Arthritis as demonstrated in swellings and deformities observed in this self-portrait
An image I often use in my teaching to student of clinical aspects of RA
#rheumatologyandart #teachingpearls
#EULAR23 @RheumNow https://t.co/xwDisTUHdy
Aurelie Najm AurelieRheumo ( View Tweet)
Herpes Zoster vaccination in RA patients treated with Upadacitinib and MTX showed a satisfactory response,
slight reduction in response compared to general population in both antibody and cell mediated responses Winthrop K, Abst#OP0225 #EULAR2023 @RheumNow https://t.co/wxwbOYsn5K
Dr. Antoni Chan synovialjoints ( View Tweet)
Let le introduce you to ARTHUR 🤖
A very skilled robot who scans your hands and wrists in 15 mn 🤚
Amazing to see new #AI developments that will make our lifes’ easier!
#EULAR23 @ROPCA3 @JustSoren Stand M6
@RheumNow https://t.co/7PtR2CGqTt
Aurelie Najm AurelieRheumo ( View Tweet)
So what kind of changes do we see in ACPA+ arthralgia patients, in the 6 months prior to them developing inflamm arthritis?
- ACPA titre up, RF pos
- EMS, pain up
- ESR up
Good things to keep an eye on in pre-RA
Emery group POS1046 #EULAR2023 @RheumNow https://t.co/cSKPb5SbVH
David Liew drdavidliew ( View Tweet)
‘Where have all the rheumatoid nodules gone?’
(Fantastic poster title @MayoClinic)
Don’t get to see them much in clinic anymore. Almost surprised when I do
Smoking is down
Therapies are better
RA is changing
(a fact worth remembering!)
POS1066 #EULAR2023 @RheumNow https://t.co/VxDNusIjOa
David Liew drdavidliew ( View Tweet)
#EULAR2023 #POS1069 SLR & meta-analysis to inform EULAR Points to Consider which included 15 studies showed that targeted therapies were not associated with increased risk of cancer recurrence in patients with inflammatory arthritis AND a historyof cancer (85% had RA) @RheumNow https://t.co/uK2XHLjpj8
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
‘Clinically suspect arthralgias: fact or myth’ - a great debate topic #EULAR2023
First, the argument for. And we start with a reminder as to what we really mean by CSA
@RheumNow https://t.co/e1CdxKi69m
David Liew drdavidliew ( View Tweet)
To treat or not? Clinically suspect arthralgia does affect QoL including function. Both premises of treating with a DMARD are valid. OverRx v missing the very early window of opportunity @RheumNow #EULAR2023 @eular_org https://t.co/86CVZ2IjEf
Janet Pope Janetbirdope ( View Tweet)
Use of antîmalarials in RA reduced the risk of bacterial infection in RA, smaller number of viral and fungal to study impact on systematic infections Bredemeier M, Abst#OP223 #EULAR2023 @RheumNow https://t.co/RXuFi3LdZC
Dr. Antoni Chan synovialjoints ( View Tweet)
Natural sequence of events happening in a subclinically inflamed joint, serial MRI study
When progressing to clinical RA
First osteitis then synovitis & tenosynovitis
🦴➡️✋
During resolution tenosynovitis reduces first then synovitis & osteitis
@RheumNow #EULAR23 OP0261 https://t.co/ic94htYv6T
Aurelie Najm AurelieRheumo ( View Tweet)
We know HCQ adherence is poor in both RA and SLE
>50% in this BC 🇨🇦 cohort
All despite being such an important medicine
What’s super interesting are the trajectories of adherence - and we’d like to understand more about what motivates each group
OP0222 #EULAR2023 @RheumNow https://t.co/rbx1l9T36C
David Liew drdavidliew ( View Tweet)
Antimalarial adherence in RA and SLE showed 4 patterns of adherence over time, with 53% drop off in 1 year, with higher adherence with age, SLE and socioeconomic class, Hoque MR, Abst#0222 #EULAR2023 @RheumNow https://t.co/Bld5kWVQxE
Dr. Antoni Chan synovialjoints ( View Tweet)
#EULAR2023 #POS1075 Which biologics have the lowest retention rate in Elderly patients (=>65 yrs) in Rheumatoid Arthritis? Data from Italian registry showed 1/3 discontinued biologics at 2 yrs. IL6-i: lowest persistence; Abatacept: highest @RheumNow https://t.co/28n4qzR3aM
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
So we need protocolized extra steroids in new RA? A debate as old as time
Individual patient data metaanalysis
- slight gains early on, not sustained
- fewer DMARD changes
- but a heap more PNL, well after the protocol ends
Life is about trade-offs😐
OP0220 #EULAR2023 @RheumNow https://t.co/M8SBKjGncv
David Liew drdavidliew ( View Tweet)
#EULAR2023 #POS1066 “Diagnosis: Seropositive Nodular Rheumatoid Arthritis” - I can probably get rid of Nodular soon in my letter. Trends of Nodules have decreased over time. Could be because we are getting better at preventing erosion and smoking cessation @RheumNow https://t.co/fmQvyNHCUJ
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Impact of menopause & on function in RA
HAQ increases slightly after menopause
Premature menopause = worse function
Slightly better HAQ (but moderate & no effects on other PROs) in THR group vs. non THR
No safety data
@RheumNow OP0268 #EULAR23 https://t.co/7KJScF8O2X
Aurelie Najm AurelieRheumo ( View Tweet)
Initial use of glucocorticoids GC as bridging treatment in RA resulted in increase use of GC later, fewer DMARD changes later, van Ouwerkek L, Abst#OP220 #EULAR2023 @RheumNow https://t.co/IjxgQTZ8SE
Dr. Antoni Chan synovialjoints ( View Tweet)
We need to assess CV risk in IA but how?
Performances of QRisk3, Framingham & Reynolds scores for prediction of CV event in OA RA PsA AS PSO
Bummer: these 3 prediction tools are less accurate in IA but also OA.
We need a dedicated tool.
@Rheumnow OP0267 #EULAR23 https://t.co/O73cETXXoe
Aurelie Najm AurelieRheumo ( View Tweet)
