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Hypertension not associated with High NSAID Doses in AxSpA
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Medscape
At the recent SPARTAN annual meeting in Cleveland, Dr. Jose Meade-Aguilar reported that amongst axial spondyloarthritis patients receiving nonsteroidal anti-inflammatory drugs, there was no difference in the risk for hypertension when comparing those on high vs. low dose NSAIDs.
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The Window of Opportunity (5.24.2024)
Dr. Jack Cush reviews the journal reports and news from the past week on https://t.co/V10S4oVFsv. This week: blockbuster drugs, opioids in rheumatology and nontreatment of inflammatory arthritis?
https://t.co/zSjb2tKPWY
Dr. John Cush RheumNow ( View Tweet)
Preliminary results of ph IIB ORIGIN trial of placebo vs Atacicept (binds BAFF & APRIL)in 166 pts w/ IgA Nephropathy (Berger’s Dz) Gd-IgA1, hematuria, and UPCR (vs PBO) in the blinded 1st 36 weeks of the trial. https://t.co/tPhCrSaSTC https://t.co/6HqGFtb1IE
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Dr. John Cush RheumNow ( View Tweet)
NHANES study of 2500 #RA pts, found a significant correlation between an inflammatory diet (meas by DII score) and inflammatory indices like systemic immune-inflamm Index (SII) & neutrophil-lymphocyte ratio (NLR) https://t.co/sWXZRrG6hV https://t.co/9IcLDF1Jlo
Dr. John Cush RheumNow ( View Tweet)
Gangsin: 갱신 Korean: refresh, renew, updated
Over the last 20+ years, I have listened to patients confide their personal stories. Some remained paralyzed in their current state of distress, --I was one of them
https://t.co/Tr9w1XpWL0 https://t.co/E3kLnvfqOb
Dr. John Cush RheumNow ( View Tweet)
Untangling the relationship between smoking and systemic sclerosis: an analysis of the EUSTAR cohort
https://t.co/IB0cOAFnwl https://t.co/zpwm3JRKU4
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Nelly ZIADE 🍀 Nellziade ( View Tweet)
The ability to predict hip fractures just went to a new level
https://t.co/k9cAPIJigd
A proteomic risk score was found to be strongly predictive of incident hip fractures in multiple independent populations
@NatureAging https://t.co/WZemPZqsev
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Eric Topol EricTopol ( View Tweet)
Available online, open access:
A review of CAR-T call therapy in rheumatic disease by @RyuOhno06
See below diagram of CAR-T therapy mechanism in cancer.
https://t.co/WALWulEDkW https://t.co/k1FD0zHtWu
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Seminars in Arthritis and Rheumatism seminarthrheum ( View Tweet)
Congratulations to CRA member Dr. Andrew Chow, recipient of the Ontario Rheumatology Association's Rheumatologist of the Year Award! 🏆👏 https://t.co/2fB77VOBhv
CRA SCR CRASCRRheum ( View Tweet)
Treatment of psoriasis with different classes of biologics reduces the likelihood of peripheral and axial psoriatic arthritis development https://t.co/DFdQy1Rn3D
Peter Nash drpnash ( View Tweet)
Congratulations to CRA member Dr. Lauren King, recipient of the Ontario Rheumatology Association's Early Career Rheumatology Award! 🏆👏 https://t.co/iM5MxzVaTg
CRA SCR CRASCRRheum ( View Tweet)
Biomarkers Predictive of a Deucravacitinib Response in PsA
A phase II trial demonstrating the clinical efficacy of deucravacitinib, a TYK2 inhibitor, in PsA suggests specific biologic effects identified by biomarkers may predict clinical responses.
https://t.co/zsZl7JQydn https://t.co/4mGBYB4qU4
Dr. John Cush RheumNow ( View Tweet)
Lupus Research Alliance Grants for Lupus Innovation
The LRA) is proud to announce that nine international researchers are the recipients of this year’s Lupus Innovation Award (LIA).
https://t.co/v3S8u8aVvr https://t.co/Ve7OcIJT03
Dr. John Cush RheumNow ( View Tweet)
Save the date! We are covering #EULAR24 ! Will we see you there? https://t.co/aMGYnPxlXh
Dr. John Cush RheumNow ( View Tweet)
No Link Between Autoimmune Diseases and Monoclonal Gammopathy of Undetermined Significance
Annals of Internal Medicine reports a study of more than 75,000 persons screened for MGUS and found no association between AIRD and MGUS.
https://t.co/F8diWbUYPf https://t.co/M53Dgphcge
Dr. John Cush RheumNow ( View Tweet)
Australian multicenter KARAOKE RCT of 262 adults w/ Knee OA (w/ MRI effusion/synovitis) Rx w/ placebo vs , 2 g/d of krill oil showed no significant benefit in pain VAS score, −19.9 [krill oil] vs −20.2 [placebo]. https://t.co/aeNcVM0p8J https://t.co/2PR0PG6eWj
Dr. John Cush RheumNow ( View Tweet)
Upside/Downside of Steroids in Lupus Nephritis
A systematic review of randomized clinical trials of patients with biopsy-proven lupus nephritis (LN) demonstrates both the benefits and harms to early glucocorticoid (GC) regimens on lupus outcomes.
https://t.co/T88365IT9r https://t.co/xe5AmErLy2
Dr. John Cush RheumNow ( View Tweet)
384 Psoriasis pts followed mean 33 mos, 56 (14.6%) developed new-onset PsA. 311/384 (81%) had arthralgia (subclinical PsA) & 9.4% got PsA within 12 mos (23% by 36%). Subclinical more likely than PSO to get PsA (OR 11.7) https://t.co/9t41cjROwW https://t.co/9AelBwoRzs
Dr. John Cush RheumNow ( View Tweet)
Full read review of the benefits & impact of hydroxychloroquine in #SLE. Benefits on:
- T cells, cytokines, TLR signaling
- VTE prevention
- Decr CV risks
- Glucose & lipid benefits
- Pregnancy
https://t.co/bio9cYCIeb https://t.co/zfyUBaecbu
Dr. John Cush RheumNow ( View Tweet)
Brazilian Registry of Spondyloarthritis study of 1096 SpA pts, found 73% HLA-B27 positivity. B27+ signif assoc w/ males, earlier onset/Dx, uveitis, +FHx. B27 negativity assoc w/ psoriasis, higher peripheral arthritis/disease activity, worse QOL, mobility https://t.co/OUOVozdoXw https://t.co/z8hhPjRUfx
Dr. John Cush RheumNow ( View Tweet)