Psoriasis to Psoriatic Arthritis: Interim Results of the PRESTO Study

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Early diagnosis of arthritis improves outcomes and quality of life in patients with psoriasis. A longitudinal cohort study shows that the development of PsA within clinically meaningful time frames can be predicted with reasonable accuracy for psoriasis patients.

Industry Abstract Previews - ACR2020

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Each pharmaceutical company has spent months and years preparing to present and highlight their featured clinical trials and abstracts at ACR 2020.  This is our selection of their best studies for you to review and evaluate as part of your to-do list.

QD Clinic Podcast - 106 thru 109

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Here is the last of our QD Clinics in Podcast form, just before we start ACR2020 coverage.

In this compilation from the past week we talk about

- HIV and arthritis

- Hyperuricemia in PsA

- An odd kind of dermatomyositis

TNF Inhibitor Associated Infectious Risk Greatest in First 6 Months

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The risk of serious infections (SIE) in RA patients given anti-TNF (TNFi) therapy is not static, instead it has been shown to be greatest in the first 6 months of use according to a recent report in Rheumatology. 

ACR 2020 Your Way - Get Your Topic Emails

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ACR is but a few days away; the question is: how will you tackle this virtual meeting? RheumNow has created several options for learning the way you want to. First is to feed your need. Are you a lupologist? A gout maven? A Spondylitis sleuth? A drug safety wannabe?

Long-Term Benefits of Ixekizumab in Psoriatic Arthritis

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The SPIRIT-P1 study has demonstrated the safety and efficacy of ixekizumab (an IL-17A antagonist) when given to adults w/ active psoriatic arthritis (PsA), and also demonstrating radiographic protection and improvement in skin outcomes as well. 

SPARTAN ACR20 Recommendations on Spondyloarthritis

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SPARTAN has compiled a list of presentations and sessions worth seeing if you are interested in ankylosing spondylitis, spondyloarthritis and related disorders.

US Differs from Worldwide Drug Reimbursements

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"The US has nearly 4.5% of the world’s population but accounts for more than 40% of global drug spending" reports JAMA Internal Medicine.  US drug prices are nearly double those of Australia, Canada, and the United Kingdom, and the US spends twice as much on retail and nonretai

RheumNow Podcast – ACR 20 is Coming to Town (10.30.20)

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Dr Jack Cush overviews the RheumNow commitment, upcoming bonus coverage of ACR20 and the good news and journal reports from the past week on RheumNow.com

Guselkumab, an IL-23 Inhibitor, Effective in Psoriatic Arthritis

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The DISCOVER‐2 trial has shown that guselkumab, an interleukin‐23p19 was shown to be safe and effective in biologic‐naïve psoriatic arthritis (PsA) patients in a one year study.

RheumNow Podcast – Good Time Charlie…. (10.16.20)

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Dr. Jack Cush sings the news and journal reports from the past week on RheumNow.com.

Tofacitinib and Thromboembolic Risk

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Mease and colleagues have reviewed the tofacitinib drug development and clinical trial data, finding the risk of venous (VTE) and arterial thromboembolism (ATE) to be low and augmented in patients with baseline cardiovascular abd VTE risk factors and those taking higher doses of tofacitinib (10 m

RheumNow Podcast – Bad Disease & Bad Outcomes (10.9.20)

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Dr. Jack Cush Reviews the news and journal articles from the past week on RheumNow.com.

RheumNow Podcast – Function Follows Form (10.2.20)

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Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com. Regulatory approvals, update on global rheumatology alliance, smoking and psoriasis, gabapentin let down and defining difficult RA.

Low Risk of Latent TB with Secukinumab

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TB reactivation and latent tuberculosis infection (LTBI) are warned against with biologic agents, especially TNF inhibitors; yet clinical trial data now shows that the risk of LTBI with IL-17 inhibition via secukinumab is uncommon.