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UK Biobank case control study of 15 871 pts with Gout and COVID. Gout associated with diagnosis of COVID-19 (OR 1·20; CI 1·11–1·29) but not with risk of COVID-19-related death in the cohort of patients diagnosed with COVID-19 (1·20, 0·96–1·51). https://t.co/dN5YnIqhzD

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Dr. John Cush RheumNow ( View Tweet)

Should we use colchicine in COVID-19? Mainly mixed results; not likely effective in sick hospitalized patients but may have utility in early infections https://t.co/wecWjSIbEG

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Dr. John Cush RheumNow ( View Tweet)

ICYMI: NEJM study of ~2000 persons showed that prior PCR proven SARS-CoV-2 infection was effective at preventing Symptomatic Reinfection against alpha variant (90.2%), beta ( 85.7%), delta (92%), but not omicron variant (56%). https://t.co/UkvDUH6alK

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Dr. John Cush RheumNow ( View Tweet)

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Hand OA and Heroes in Rheumatology (2.11.2022)

d Jack Cush, MD

Interesting reports this week about dementia, who gets hand OA and a great list of women Heroes and Pillars of Rheumatology. Tune in as Dr. Jack Cush reviews the news and journal articles from this past week in RheumNow.com.

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Video computer laptop call telehealth telemedicine

Recommendations on Telemedicine in Rheumatology

d Jack Cush, MD

The integration of Telemedicine in to rheumatologic care was ignited by pandemic restrictions in early 2020 and since the advantages and disadvantages have been debated.

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NEJM study of ~2000 persons showed that prior PCR proven SARS-CoV-2 infection was effective at preventing Symptomatic Reinfection against alpha variant (90.2%), beta ( 85.7%), delta (92%), but not omicron variant (56%). https://t.co/xlyGmJPRnj

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Dr. John Cush RheumNow ( View Tweet)

Hip fractures in elderly occur at >250 000/YR in US w/ a 1-yr mortality rate, 12%-37%. During COVID-19, surgery volumes among older individuals were lower than 2 years previously starting spring 2020 until vaccine was widely available https://t.co/80YQq1gyhA

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Dr. John Cush RheumNow ( View Tweet)

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An Ounce of Prevention (2.4.2022)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.  He discusses the GI side effects of IL-17 inhibitors, downstream revenues from rheumatology care and dietary prevention of gout. 

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Persons living with diagnosed HIV (PLWDH) have more hospitalizations and death from COVID-19 than those not HIV+. In 100K PLWDH, 63%) were fully vaccinated, 4% partly Vax & 32% no Vax. VAX in PLWDH was lower than gen population (63% vs 75%) https://t.co/oegf5WjmNF

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Dr. John Cush RheumNow ( View Tweet)

FDA has expanded its approval of REMDESIVIR for use in non-hospitalizedadults and pediatric patients for the treatment of mild-to-moderate COVID-19 disease. Previously, Veklury was limited to hospitalized COVID-19 pts. https://t.co/dHbomchfB5

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Dr. John Cush RheumNow ( View Tweet)

ACR, guidance, guidelines

ACR Newly Revised COVID-19 Vaccine Clinical Guidance for RMD Patients

d ACR

The ACR has updated its clinical guidance for the use of COVID-19 vaccination in patients with musculoskeletal disorders (MSK). 

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Following a mild bout of COVID-19, Dr. Kathryn Dao, shares insights on the best way to handle mild cases whether it is yourself or a friend/family member who has COVID19. https://t.co/mevbQVNjPp ( @KDAO2011) https://t.co/CSzB9ChH3r

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Dr. John Cush RheumNow ( View Tweet)
ICYMI: MMWR reports >40,000 pregnant women who received COVID-19 vaccination during pregnancy- VAX not associated with preterm birth or small-for-gestational-age at birth overall compared with unvaccinated pregnant women. https://t.co/GtRMsNrFnn

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Dr. John Cush RheumNow ( View Tweet)

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The Last Word on JAK Inhibitor Safety & 1133 Study (1.28.2022)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.  This week a trifecta of Gout reports and the last word on the ORAL Surveillance study...

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virus,COVID,Vaccine, booster

MMWR: Booster Vaccine Efficacy in Immunosuppressed Patients

d CDC/MMWR

For adults aged ≥18 years who received 2 doses of an mRNA COVID-19 vaccine, a third dose increased vaccine effectiveness (prevention of hospitalization) among adults without (82% to 97%) and with immunocompromising conditions (69% to 88%), with near similar efficacy.

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From 1969 hospitalized COVID Spanish pts (46% F, age 61), 31 pts w/ preexisting RMD -- they did not have more long-term post-COVID sxs (OR 1.46; 0.89–2.4), functional limitation (OR 1.058), anxiety, depression or MSK pain vs non-RMD https://t.co/IYJz5zFoLe

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Dr. John Cush RheumNow ( View Tweet)

ICYMI: JAMA reports that between Dec 2020 and July 2021, COVID-19 vaccination saved nearly 241,000 lives, prevented 1, 133, 617 hospitalizations and prevented more than 14 million COVID-19 cases (all in 1st 6 mos of the COVID vaccines) https://t.co/q9TvLjtY9p

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Dr. John Cush RheumNow ( View Tweet)

3rd Vaccine Dose May Benefit ANCA-Associated Vasculitis Patients https://t.co/UXUryaQ7Fz https://t.co/p40xND4lVP

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Dr. John Cush RheumNow ( View Tweet)
syringe,needle,vaccine

3rd Vaccine Dose May Benefit ANCA-Associated Vasculitis Patients

d Jack Cush, MD

ARD has publish a prospective, multicenter, observational study of vaccination outcomes in antineutrophil cytoplasmic antibodies associated vasculitis (AAV) patients, showing that AAV patients may not be adequately protected after standard two-dose COVID-19 vaccination, but that a third

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How's the United States doing on boosters? Trailing a long list of countries, including Serbia, Slovenia, and Lithuania @OurWorldInData https://t.co/cOCVoyuqT3
Eric Topol EricTopol ( View Tweet)

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