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Industry Abstract Previews - ACR2020

Jack Cush, MD

Each pharmaceutical company has spent months and years preparing to present and highlight their featured clinical trials and abstracts at ACR 2020.  This is our selection of their best studies for you to review and evaluate as part of your to-do list.

Robert B Chao, MD Tweet
doctorRBC
Dr. Aggarwal Abs#0955 showed efficacy of IVIG in tx of Dermatomyositis. How/when do you use IVIG for tx of DM? @RheumNow #ACR20
Robert B Chao, MD Tweet
doctorRBC
Efficacy of IVIG in Dermatomyositis Treatment 1st Placebo controlled RCT 1️⃣79% responder by total improvement score vs. 44% 2️⃣Efficacy sustained thru wk 40 3️⃣6% serious AE - thromboembolic event @RheumNow #ACR20 Abs#0955 #ACRbest https://t.co/715h1UkZ9X
sheila Tweet
RHEUMarampa
ProDERM study:10% IVIG is effective and safe in pts with DM. First large PBO-controlled, randomized ph 3 trial. @RheumNow #ACR20 abs0995 #ACRbest https://t.co/aJyASaAMlJ
Dr. John Cush Tweet
RheumNow
Olmstead County (Mayo) population study shows 47 lupus nephritis (LN) pts betw 1976-2018. Incidence doubled from 1980s (0.6 per 100K) to 2018 (1.2/100K); with women of childbearing age as the most affected group. #ACR20 Abstr#0274 https://t.co/uhAMd0EtJl
k dao Tweet
KDAO2011
Dr. C Mohan @UTSWNews #ACR20 @rheumnow reviews IFN in SLE: 👉Diff't IFN assc w/diff't lupus manifestions 👉⬆️stim endosomal DNA/RNA sensors RLR7,8,9 may drive SLE 👉TLR7 & 9 in B cells impt for germinal ctrs & Ab prod’n 👉TLR7 is X-linked 👉IFNsig not track w/dz activity https://t.co/3KK3UvH8Ka
k dao Tweet
KDAO2011
#ACR20 Abstr#0433 #PlenaryACR Georgia SLE registry 336 pts ⬆️stroke/isch heart dz with: 👉3X stroke risk and 24X IHD risk for black pts 👉predictors stroke: black race, DLE, renal dz 👉predictors IHD: age>65, black race, neuro & immuno d/o (e.g, APAs) @RheumNow https://t.co/u6Ky7r0FYF
Bella Mehta Tweet
bella_mehta
Plenary session 1 no#2F011 #ACR20 @rheumnow Black #SLE patients have a 3 fold higher stroke and 24 fold higher Ishemic Heart Disease risk! https://t.co/AYtiXk7pDa
Janet Pope Tweet
Janetbirdope
#hydroxychloroquine is not a ‘cutie’ drug. E Park et al showed that HCQ does not increase QT interval in RA & SLE patients including if on other meds that may affect QT but known heart disease excluded from study #ACR20 #ACR2020 @RheumNow abstr#432 @CRASCRRheum https://t.co/FGVPknmj5q
k dao Tweet
KDAO2011
Dr. G Gilkeson #Klempererlecture #ACR20 @rheumnow There is a lupus gradient b/t Africa and US: we are seeing more SLE in the US (genetics? environmental? diet?)
Eric Dein Tweet
ejdein1
Dr. Gilkerson in 2F010- Lupus in Unusual Places at #ACR20- Is it environmental or genetics that explain differences between African and African-Amer populations? Study the population (Sierra Leone), but do so with cultural sensitivity. @RheumNow https://t.co/B1ikkQgCuk
Janet Pope Tweet
Janetbirdope
Do you routinely use septra/bactrim in SLE to prevent PCP/PJP? @RheumNow @CRASCRRheum
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