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Safety of Azathioprine in SLE Pregnancy Studied
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Sildenafil May Help Heal Scleroderma Ulcers
A prospective study of sildenafil was conducted in 25 centers that included 83 patients and 192 digital ulcers at entry. The odds of healing ulcers was less, but not significant, for sildenafil.
Read ArticleInflammatory Fibromyalgia - Is it Possible?
Fibromyalgia is a noninflammatory disorder. However, there are patients with prolonged morning stiffness, subjective joint swelling and many with modest-to-moderate elevations of acute-phase reactants.
Read ArticleThe Real Prevalence of Sjogren's Syndrome
The population prevalence of Sjogrens syndrome is 0.2%, with an incidence of 4 cases per 100,000 per year. Sjogrens is 20 times more common in females than males.
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Sjogrens Syndrome and Familial Risk
A population based study from Taiwan shows that Sjogren's syndrome, to have a prevalence of 0.05%. The prevalence of the syndrome, however, was 10 times higher among women (0.10%) compared to men (0.01%). Overall, having an affected first-degree relative with Sjogren's syndrome carried
Read ArticleThe Danger Model as an Alternative Cause of Autoimmunity
The danger model was proposed by Matzinger as an alternative (or complement) to the traditional self-non-self (SNS) model of autoimmunity.
Read ArticleDrug-Induced Lupus is Rare with TNF inhibitor Therapy
A different point of view on RA
Professor Fergus Shanahan, a consultant gastroenterologist and professor of medicine at University College Cork, has an issue with the label “auto-immune” disease being applied to conditions such as RA, lupus, multiple sclerosis, Crohn’s disease, asthma and type 1 diabetes.
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Hemophagocytic Syndrome in Adults
Hemophagocytic lymphohistiocytosis(HLH) is a rare complication of many disorders. In children, systemic JIA is by far the most common cause of HLH.
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