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Methotrexate to Prevent RA, Clear as Mud

d Richard Conway, MBBChBAO, PhD

Intervention in individuals predisposed to develop RA, with a holy grail of prevention of RA, has long been a hot topic. The 4-year results of the TREAT EARLIER study, presented at Tuesday’s oral abstract session, show that methotrexate appears to prevent the development of RA in high risk ACPA- patients.

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artificial intelligence machine learning computer

Predicting flares in rheumatic diseases with machine learning

d Antoni Chan, MD, PhD

Rheumatic diseases, such as axial spondyloarthritis (axSpA) and rheumatoid arthritis (RA), are marked by unpredictable disease flares that adversely impact quality of life and long-term outcomes.

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light bulb idea

How New Medications are Reframing Imaging Abnormalities in axSpA

d Brian Jaros, MD

Bimekizumab (BKZ), a monoclonal antibody that selectively targets both IL-17A and IL-17F, was evaluated in the BE MOBILE 1 (non-radiographic axSpA) and BE MOBILE 2 (radiographic axSpA) trials and found to yield significant cli

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Prgnancy,outcome

Improving fertility in women with RA

d Jiha Lee, MD

For many women, the journey to motherhood brings a sense of anticipation and joy. However, for those with rheumatoid arthritis, this journey presents unique challenges. At ACR Convergence 2024, researchers discussed how advancements in reproductive medicine and RA management are paving the way for improved outcomes.

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men and women

Sex related differences in PsA

d Adela Castro, MD

Different factors are known to influence disease characteristics and outcomes in psoriatic arthritis (PsA).

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Beyond the Needle: Redefining the Assessment of Lupus Nephritis Lupus nephritis is one of the most silent and severe manifestations of systemic lupus erythematosus (SLE). https://t.co/fvGG0BZbOL #ACR24 https://t.co/wPXQz9Vese

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Dr. John Cush RheumNow ( View Tweet)
Cancer Survival in RA Dr. Eric Dein interviews Joshua Hsieh about abstract 0474, Association Between Rheumatoid Arthritis and Survival After Cancer: A Systematic Literature Review and Meta-analysis, presented at #ACR24. https://t.co/2957Nq6Ajy https://t.co/3swVyigA3g

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Dr. John Cush RheumNow ( View Tweet)
COVID Associated Immune Disease Dr. Len Calabrese reports on a session he participated in discussing if Covid-19 is associated or causal for autoimmune disease. Reporting from #ACR24 https://t.co/vFdlf9XVzf https://t.co/JhpglNVIt7

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Dr. John Cush RheumNow ( View Tweet)
Finding the Right Combination Therapy in RA Dr. Jonathan Kay interviews Dr. Ernest Choy about abstract 0521, Transcriptome Analysis of Drug Response in a Large Cohort of Immune-Mediated Inflammatory Disease Patients Supports Advanced Combination Therapy in RA, presented at… https://t.co/yPmDIZ6aKI https://t.co/cairKrbDDu
Dr. John Cush RheumNow ( View Tweet)
RheumNow Day 4 Recap: ACR Convergence 2024 Highlights https://t.co/WvQB7y0bkm

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Dr. John Cush RheumNow ( View Tweet)

RheumNow’s expanded coverage of the #ACR24 annual meeting is sponsored in part by Novartis. All content is chosen by RheumNow & its faculty

Dr. John Cush RheumNow ( View Tweet)

RheumNow’s expanded coverage of the #ACR24 Annual meeting is sponsored in part by Novartis. All content is chosen by RheumNow & its faculty

Dr. John Cush RheumNow ( View Tweet)

Time the💉 Response to pneumococcal vaccine better when given before starting MTX. Stay updated on ACR and EULAR vaccination recommendations! #ACR24 @RheumNow ABST#2676

Jiha Lee JihaRheum ( View Tweet)

How long before starting MTX should pts receive PCV13 vaccine? ➡️In RA, PCV13 vaccine given 1 month before starting MTX led to significantly higher immunological response at 1 month compared to pts vaccinated on MTX ⏩Vaccinate pts before starting MTX Ab2676 #ACR24 @RheumNow

Mrinalini Dey DrMiniDey ( View Tweet)

Abstract 2681: #SDOH factors & SLE risk: - Low income (AOR=2.779). - By race/ethnicity NHB (AOR=2.429), Hispanic (AOR=1.616). Behavioral: Psych distress (AOR=2.127), no exercise (AOR=1.677). Access: Medicaid (AOR=2.540), transport barriers (AOR=20.394). @RheumNow #ACR24

Akhil Sood MD AkhilSoodMD ( View Tweet)

For daily recaps, content and updates from #ACR24 head to https://t.co/eL0bMhnFiu @RheumNow with input from colleagues in the faculty @synovialjoints @bella_mehta @ericdeinmd @AkhilSoodMD. @DrMiniDey @CaoilfhionnMD @ebrhuem @rheumarampa @Dr_Brian_MD @AdelaCastro222 @JihaRheum… https://t.co/a3FQjGokhn https://t.co/1g3Fi01HWG

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Antoni Chan MD (Prof) synovialjoints ( View Tweet)
#Ianalumab 300 mg sc q monthly B cell depleted and changes BAFF signalling 👇⬇️IFN May be promising in #lupus #SLE +data in primary #Sjogrens ACR24 @RheumNow @ACRheum Abst#2425 Needs Phase3 ➡️I suspect safer than CAR T and Bispecific T cell engagers but ? ⬇️efficacy

Janet Pope Janetbirdope ( View Tweet)

ACR24 take homes ➡️#Inflammatory #myositis #Upadacitinib improved MDA5 ILD #Baricitinib 4mg/d good in myositis delayed start #RCT #Tofacitinb ➡️help for skin, calcinosis, rash in case series ➡️RCT ongoing JAKi is ‘jacked’ in muscles 💪🏿 #ACR24 @RheumNow @ACRheum 1731 0348

Janet Pope Janetbirdope ( View Tweet)

Biggest absence award at #ACR24 @ACRheum @RheumNow 🥇 Absence of discussion on 👇 #Oral #Surveillance Except for maybe Monitoring for mouth ulcers and cancers issues are not resolved but we are comfortable with ambiguity!

Janet Pope Janetbirdope ( View Tweet)

Taking CAR-T for a Test Drive What is CAR-T? How can you get a healthy dose of it at #ACR24? And what does it mean for the future? Read on to find out! https://t.co/TnNHzWQndp https://t.co/qWgwjiEdLF

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Dr. John Cush RheumNow ( View Tweet)

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