Treat-to-target strategies are not a new concept in rheumatology. It has shown to improve patient outcomes and quality of life in RA and PsA, and is now being increasingly adopted not only in SLE research but also in clinical practice. This article reviews key highlights from Dr. Eric Morand’s plenary session lecture on Treat to Target in SLE: Current Evidence and Future Directions, presented during the recent APLAR 2025 Congress.
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sheila
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An important message from Prof. @XBaraliakos on D2M-axSpA:
Re-evaluate your diagnosis & check for comorbids before labelling pts as tx-refractory or difficult-to-manage.
consider other causes: FM, other causes of pain
@RheumNow #APLAR25 @rheumarhyme @marklagacmd https://t.co/Lo0yShOK0P
Aurelie Najm
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Drivers of costs associated with economic costs of RMDs in Asia Pacific
-Traditional medicine
-Loss of income much higher if worker as opposed to unpaid household labor so high impact of gender roles
-Impact of out of pocket health payments due to « catastrophic spendings » in https://t.co/sptwGE7J2V
sheila
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Prof. Aletaha shares their AutoPiX project - using AI to develop quantitative biomarkers.
Something to look forward to since imaging remains an important diagnostic tool in #rheumatology
@RheumNow #APLAR25 @rheumarhyme https://t.co/WExT9amazz
Aurelie Najm
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Update on Rheumatology workforce shortage in Asia-Pacific
Date presented by Dr Ahmad
Number of Rheumatologists per 100000 inhabitants across @APLAR_org countries
-3 in Japan
-1.3 in Australia, Hong Kong, Singapore
-0.03 in Pakistan
As a result: delayed diagnosis for patients! https://t.co/Hycqtp8BtY
Aurelie Najm
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Peter Taylor on extra articular manifestations of RA
Keep an eye on RA patients’ glomerular function
RA patients have increased risk of CKD
Systematic review >1million pts
Risk Ratio 1.52
@RheumNow #APLAR25 https://t.co/5iZwtmvwSR
Hyperferritinemia is common in Hyperinflammatory syndromes but is a hallmark of Macrophage activation syndrome and Sepsis; and is a poor prognostic sign too. MAS is excessive activation of T-lymphocytes & macrophages leading to cytokine storm & multi-organ damage. https://t.co/MUKXC0Tw3M
🆕 Intro to ILD (Part I): the essentials
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🔬 Key pathology patterns
🧑⚕️ Clinical approach
📋 What rheums need to know
⬇️ Download & learn more: https://t.co/7RzpTDOjwa
Created by @MithuRheum | via @RheumNow for our Rheum to Breathe: ILD Campaign https://t.co/D9d97bqcD5
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Lessons Learned in Neuropsychiatric SLE
Dr. Sheila Reyes, The Philippines, reports highlights from a session on neuropsychiatric systemic lupus erythematosus, presented at the APLAR 2025 Congress in Fukuoka, Japan.
https://t.co/Dh1GQnBhvg https://t.co/wX5FgpIq7C
PAH diagnosis and management in the context of CTD ILD
Pulmonary arterial hypertension (PAH) is a serious complication of connective tissue disorders (CTD), affecting about 25% of PAH patients. CTD-PAH is the second most common cause after the idiopathic form. PAH involves high https://t.co/UgsdYWv02S
QD Clinic Video: RA and Bronchiectasis
Dr. Jeffrey Sparks, Boston, talks about rheumatoid arthritis and bronchiectasis as part of RheumNow's Rheum to Breathe: ILD campaign, presented throughout the month of September 2025.
https://t.co/Y2u3m4rFfj https://t.co/KgrIxXlQo4
TNR: Future Treatment of ILD
This Tuesday Night Rheumatology webinar reviewed ACR and EULAR guidelines on interstitial lung disease, with a focus on ‘where are we now and where are we going?’ in regards to treatment strategies and emerging therapies in ILD care. https://t.co/F1fJhWgR5O
AbbVie's US patent protection for Rinvoq (upadacitinib) will run till April 2037. SEC filing shows AbbVie has reached an agreement with generic manufacturers challenging Rinvoq patents. UPA is their 2nd leading product with nearly $3.75 billion worldwide sales in 1st 1/2 of
Antifibrotics - A New Class of Therapies in Rheumatology?
Rheumatologists typically manage systemic autoimmune rheumatic diseases (SARD) and associated interstitial lung disease (ILD) with immunosuppressants. However, evidence increasingly supports also the use of antifibrotic https://t.co/IobQagC0ZE
9 yr. study of anti-Ro52 & ILD pts -- 1,026 pts 15% Ro52+: interstitial pneumonia w/ autoimmune 48%, CTD-ILD 13%, idiopathic pulm fibrosis 10%, hypersens pneumonitis 6%, idiopathic ILD 24%. Ro52+ were younger w/ more autoimmune dz, +MSA Abs, ILD progression, death, & lung https://t.co/fuFfnaYIRd
Aurelie Najm
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Flow cytometry on Peripheral blood can help patient stratification in RA
A cluster rich in TEMRA Terminally Differentiated Effector Memory T Cells is associated with response to treatment and therapeutic decision taking into account showed higher remission 39% vs. 24%
Next https://t.co/8ZZ2epf7LK
sheila
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In #scleroderma pts with cardiac involvement, the presence of ventricular ectopy is assocd w/ ⬆️risk of mortality & SCD.
☝️these arrythmias present late so consider it in pts w/established dse who develop new-onset cardiac symptoms
@RheumNow #APLAR25 @rheumarhyme @marklagacmd https://t.co/MTDfxevqwb
Aurelie Najm
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2025 Update of EULAR RA management recommandation
Summary slide inspired from Josef Smolen’s presentation
@RheumNow #APLAR25 https://t.co/wRzeX9OIry https://t.co/djrd7O9G9H


