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ICYMI: The Heart of Lupus
Few people are aware of the EULAR recommendations for cardiovascular risk management in SLE published in 2022. The recommendations had 4 overarching principles: increase awareness of elevated cardiovascular risk, need for regular cardiovascular screening, assess and manage modifiable risk factors, and patient education. During ACR 2023 Convergence, several abstracts were presented evaluating the prevalence of CV disease and exploring new tools to predict CV disease.
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resolved HBV (HBsAg-, HBcAb+, HBsAb+) are at low risk of reactivation (~2%) w/ TNFi or biologics. But in a high risk endemic region (ie, Korea) this risk is higher. Study of 416 such pts HBV reactivation rate 3.5% @5 yrs, 6.1% @10 yrs & 24.2% @17 yrs https://t.co/oQ5e6O9wds https://t.co/50vBtapJVN
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Risk of Hepatitis B reactivation is assessed by serology
- Resolved HBV (low risk reactiv): HBsAg-neg, HBcAb–pos & Pos HBsAb
- If HBcAb(+), HBsAb negativity incr risk;
- HBsAg(-), HBcAb(+), HBsAb(-) negative= resolved infx, occult infx, chronic hepatitis
https://t.co/91ZwqWkdvo https://t.co/c23nN8ER1Y
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#RA pattern of synovitis is well knownn & decr in grip strength seen in Early (39%) & later RA (59% @5y). MCP1 synovitis impacts grip strength most (60%) followed by MCP4 (much less w/ tender/swelling of PIPs,other MCPs). Based on study of 215 early RA pts https://t.co/rTFBHKlNGV https://t.co/zCVsTNuYWW
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ARCTIC Rewind: Three-Year Data in RA
https://t.co/ls2e3LtlvK https://t.co/FtgSq713rc
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Rheum Fellowship Slots Fill Up for 2024
The NRMP announced yesterday that the 2024 rheumatology fellowship match filled 97.6% (124/127) of programs, and 98.9% (273/276) of rheumatology fellowship positions.
https://t.co/wTwajHyal0 https://t.co/JpgDUmioQh
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Early bird pricing has been extended! Register today!
https://t.co/wuvDqE0Qe6 https://t.co/8XXcQUBK6G https://t.co/ISRYMVdRfr
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What do you think of the concept of "dysuricemia" - the concept that both hyperuricemia and hypouricemia influence diseases. “The lower, the better” is incorrect; the ideal is to maintain normouricemia, or optimal SU level, to reduce the urate burden https://t.co/vYSNzWuPVW https://t.co/tde3Mh6Wij
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Do We Stop or Continue Treatment?
Remission had been a dream, an elusive concept. But then, with the introduction of biologics, conventional synthetic and targeted synthetic DMARDS, patients are able to live longer and with a better quality of life.
https://t.co/2ecihSwGIV https://t.co/rAjHvlyMB8
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WATCH: TMP SMX Prophylaxis in GPA
https://t.co/VEkGFUewjG https://t.co/HouepsLEuw https://t.co/r1kiXejFQn
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The SMART Study: Split Dose Oral Methotrexate
Dr. Jack Cush discusses abstract 1583 presented at the 2023 ACR Convergence meeting in San Diego.
https://t.co/STybvwt9N5 https://t.co/BTwstJiFHr https://t.co/vfb2A5zZAp
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Biologics as First-line Therapy for PMR and GCA?
Dr. Eric Dein talks with Dr. Philip Seo, one of two panelists for the Great Debate: Should PMR and GCA Be Treated with Advanced Therapies at Disease Onset?
https://t.co/eezZkBr8x7 https://t.co/D0dTSkjsNS https://t.co/nBlFyKNkHM
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Can Rheumatologists Accurately Diagnose axSpA in Patients w/Chronic Back Pain?
Chronic low back pain is a common complaint that patients bring to the doctor’s attention.
https://t.co/dnlRtjsUHl https://t.co/wQq1J4Iudf https://t.co/24dQSWlwdr
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"Protein kinases: drug targets for immunological disorders". Great full-read review from J Shea et al. Reviews Hx, biology, clinical use and safetey of Kinase targeted therapy. https://t.co/T4qMZG2DLI https://t.co/xANcLeiGr6 https://t.co/wAknXuvjl4
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Check out this engaging video exploring the pathophysiology and management of gout flares. https://t.co/wgxUIkdJ7v https://t.co/kWRGXfPeYz
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Early bird pricing has been extended! Register today!
https://t.co/DSyFGlEJZx https://t.co/T0QoRCn3tK
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PR3+ in Lupus Nephritis
https://t.co/rLdlAQYCfT https://t.co/CzLotVPwlh
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Check out this engaging video exploring the pathophysiology and management of gout flares. https://t.co/LNmXZyDec1 https://t.co/nKojprg9mU
Dr. John Cush RheumNow ( View Tweet)
Next generation JAK-inhibition strategies
As there are many JAK-inhibitors evaluated in clinical trials currently, how do you stand out?
https://t.co/Pm6cCK5ltN https://t.co/h9z3nku1gZ
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UKs MHRA issued a safety alert #MTX maybe associated w/ photosensitivity. Based on Coroners death (by secondary infx) report assoc w/ photosensitivity Rxn in a MTX Rx pt. Warning is because this is not a well-known side effect https://t.co/Vbl9BYMMNC https://t.co/9SyYQMTXTl https://t.co/JNqvNieqrt
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