All News
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@md_chawla @RheumNow https://t.co/qSdT7by1Vh
Links:
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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Erosive hand #OA may be more painful than treated #RA patients. The burden of OA is often not alked about, and this study highlights it! @RheumNow #ACR23 https://t.co/jLbvtMmgE0
Bella Mehta bella_mehta ( View Tweet)
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#ACR23 Abstr# 2489 I can’t wait for Phase 3 RCT results as I have many #SLE patients with refractory cutaneous lupus. Post-hoc analyses of Phase 2 RCT of Deucravacitinib showed its efficacy (CLASI-50) over PBO across all CLE subtypes @RheumNow https://t.co/G7edkAU18J
Md Yuzaiful Md Yusof ( View Tweet)
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And to continue
B-SAFE Clinical risk score for HCQ retinopathy 👁️ 10 years
4000+ pts, 3% retinopathy over 5yrs
Predictors of HCQ retinopathy
-body weight
-sex
-age
-eGFR
-weight based dose mg/kg
-higher cumulative dose
Risk ranges 1% to >20%
@RheumNow #ACR23 ABST2453 https://t.co/h2tl6vH9M3 https://t.co/8iuRxoVaJ0
Aurelie Najm ( View Tweet)
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Very nice to meet @KDAO2011 and @uptoTate as the faculty of Rheum Now @RheumNow tune in, follow them and listen to their interviews on the latest updates from #ACR23 https://t.co/I30wdVoqbd
Dr. Antoni Chan ( View Tweet)
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Synovitis in hand #OA
genetic
risk of synovitis predisposed to clinical and radiographic hand OA
@RheumNow #ACR23 https://t.co/aXnXD7UPnv
Bella Mehta bella_mehta ( View Tweet)
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Rheumatologist - pharmacist co-management of MTX initiators @GeisingerHealth Philadelphia
Having the dual skill set actually helped with adherence to guidelines vs standard care. Would be great to see how this works with implementation in RA clinics
#ACR23 ABST2484 @RheumNow https://t.co/88R1BYzYn5
David Liew drdavidliew ( View Tweet)
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#ACR23 Abstr# 2490 Data supporting aggressive early treatment in #SLE? Multicentre open label RCT in China showed low dose MMF + Pred 0.5mg/kg/d reduced severe flare & lupus nephritis cases vs HCQ + Pred in new onset SLE with high dsDNA but w/o major organ involvement @RheumNow https://t.co/oRlgCaOvXo
Md Yuzaiful Md Yusof ( View Tweet)
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Watch: Utility of AI and ChatGPT in Rheumatology
Dr. Kathryn Dao interviews Dr. Richard Stern at the 2023 ACR Convergence meeting in San Diego, CA. #ACR23
https://t.co/SH0TGAdvm8 https://t.co/RHu8bH9YOG
Dr. John Cush RheumNow ( View Tweet)
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TM86 #ACR23 @RheumNow
Auricular chondritis, arthritis, axonopathy, high inflamm. Initial Dx: RP
Exam: lymphadenopathy, erythema nodosum, TJC 36, SJC 4 (knees/ankles), decr sensation, asymm reflex, macular rash, nerve thicken
Skin bx: septal panniculitis wo vasc
Dx: leprosy https://t.co/P5QJArRDaA
Eric Dein ( View Tweet)
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#Cardiovascular imaging will help to detect #cardiac abnormalities earlier@in #rheumatic #diseases. #ACR23 @RheumNow @ACRheum 14T118 https://t.co/QKCpLWtkUv
Janet Pope ( View Tweet)
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🚩Adjunct therapy to treat vasculopathy of MDA5-DM
⭐️Botox heals digital ulcerations and improves Raynaud's (slide 1)
Dr. Katherine Shaw injects Botox for healing recalcitrant ulcerated Gottron's papules (example patient failed nifedipine, sildenafil, pentoxyfylline & while on… https://t.co/4XCvRrzeTL https://t.co/yxUCzS30W1
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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What do we know about IL1 drugs in #OA only a small few stidies prior to CANTOS .
COLCHCINE didnt seem to work
LoDoCO2 post hoc analysis may work? @RheumNow #ACR23 https://t.co/h4oVRppI5S
Bella Mehta bella_mehta ( View Tweet)
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Gene signature predicts RA trajectory during pregnancy:
Blood RNAseq *before* pregnancy
🚺 improve during preg: Strong Neutrophil signature
🚺 experience dis worsening:
Strong B cell signature
Needs replication but could have major implications!
@RheumNow #ACR23 ABST2481 https://t.co/gOHwEvOOM6
Aurelie Najm ( View Tweet)
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#ACR23 Abstr# 2487 How to reduce PBO response in #SLE trials? Try adding low dose GC as co-primary endpoint. Interim analysis of Phase 2 RCT: SRI-4 + sustained GC dose to ≤5mg/d or ≤BL from Wk16 to 28 was met more in Ianalumab (BAFF-R-i) vs PBO (44% vs 9%) @RheumNow https://t.co/JEnMWKilR6
Md Yuzaiful Md Yusof ( View Tweet)
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TM85 #ACR23 @RheumNow
IPF s/p lung transplant p/w diffuse bone pain
Exam: no synovitis, +crackles. Labs: ALP 203
CT chest: stable mycetoma
Xray: periosteal reaction
Dx: vericonazole periosititis
Positive Mucorales PCR, fluoride level 19 (ref <4)
Bone pain improved stopping voric https://t.co/Gt8mOAssvh
Eric Dein ( View Tweet)
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Anti-fibrotics in RA-ILD
Retro analysis of 74 pts
AEs frequent 55% and discontinuation in 46% (more than in initial RCTs)
No diff between AF
FCV trajectory mildly improved
ABST2479 @RheumNow @Juge_P_A @PhilippeDieude #ACR23 https://t.co/GqsHxkIFgD
Aurelie Najm ( View Tweet)
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Rashes in Rheumatology at #ACR23
Which disease entity are these palms pathognomonic for?
@RheumNow https://t.co/NmT1LTzWmm
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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Therapeutic Ladder for Discoid Lupus:
1. Strict🌞protection, smoking avoidance
2. Antimalarials
3. Topicals/intralesional corticosteroids, topical CNI
4. Oral steroids, retinoids, MTX, MMF
5. Thalidomide, lenalidomide
6. IVIG, JAKi, Belimumab... BUT also Anifrolumab!… https://t.co/xSw0s12Uvk https://t.co/stIJ944d9A
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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#ACR23 Abstr# 2485 Belimumab therapy in RCT was associated with increased risk of psychiatric events inc suicidality vs PBO. When compared with standard immunosuppressant, real-world data using emulated trial design showed no increased risk @RheumNow https://t.co/Vqhc5yRsSA
Md Yuzaiful Md Yusof ( View Tweet)