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ABS0155 @ #ACR23
Economic impact of switching from SQ MTX (Rasuvo) from oral MTX in U.S. RA pts?'
➡️ Rasuvo associated with significantly higher all cause total expenditure $4704 predominantly due to higher costs associated tin all cause pharmacy utilization $4,223!
@Rheumnow https://t.co/ry8XxjvHRg
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
ABS0164 @ #ACR23
Is a virtual MSK test consistent & comparable to in-person assessments w/ regard to dz activity in f/u of RA pts?
YES!
Some variability in # of swollen joints but approach shown below had good reliability & acceptable lvl of agreement
@RheumNow #ACRBEST https://t.co/yxpPb2Br4n
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
TM01 @ #ACR23: Daunting Case of Diarrhea
65 yo F w/ sero+RA + 2ndary SjS p/w 4 wks diarrhea
-CT a/p: thickening of cecum, ascending colon
-Colonoscopy path: ischemia
-R colectomy: enterocoelic lymphocytic phlebitis, no underlying vasculitis. Dx: IgG4-RD, serum IgG4⬆️
@RheumNow https://t.co/jQ57U5EjPo
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
TM02 @ #ACR23:
19yo F w/ SLE p/w 1w DOE
PMHx: SLE (malar, LN, AIHA, ITP) on HCQ x 10yrs
Dx?
HCQ-induced CM (curvilinear bodies, vacuolar degen)
⭐️RF for HCQ-induced cardio-toxicity:
- older age, F
- HCQ > 10 yrs, ⬆️ daily dose
- hx of cardiac dz
- renal insuffic
@RheumNow https://t.co/GgzB2Chgra
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
TM03 @ #ACR23
40 yo healthy F p/w swelling, red papule, hyperpigmentation, firmness, & tightness on R semi-body
Dx? Unilateral generalized morphea (UGM)
No guidelines for tx of morphea or UGM
This case report showed success w/ IVMP + PO Pred & MTX & TCZ for maint
@RheumNow https://t.co/iOVqhwmCVz
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Come and visit poster 1410 in the poster hall today. I will be sharing our work using the ASAS @Official_ASAS referral guidelines for earlier diagnosis of Axial Spondyloarthritis, Chan A et al Abst#1410 #ACR23 @RheumNow https://t.co/jB3FHPSBqs
Dr. Antoni Chan ( View Tweet)
CAR-T cell Rx show promise for drug-free remission in refractory #SLE without affecting vaccination response despite depleting CD19+ plasmablasts https://t.co/WXa4ADfcF6 abst#0606 @RheumNow #ACR23 https://t.co/ga4DCcbMhD
TheDaoIndex KDAO2011 ( View Tweet)
Argentinian #SLE Registry data eval Ro Ab & outcomes of 1500+ SLE pts. 40% had +Ro Ab. Pts w/+Ro Ab had⬇️complements, other+autoAb, Sjogren's, Raynaud's, interstitial pneumonitis, pericarditis & tended to be on steroids or MTX @RheumNow #ACR23 abst#0561
TheDaoIndex KDAO2011 ( View Tweet)
Promising! #Cenerimod is a selective S1P1 Receptor modulator has potential in SLE through modulating lymphocyte trafficking, inflammation, and autoantigen transport. Phase 2 showed reduced T/B lymphocytes, autoAb levels, and secretions of IFN-a. #abstr0584 @rheumNow #ACR23
TheDaoIndex KDAO2011 ( View Tweet)
RheumNow’s expanded coverage of the #ACR23 annual meeting is sponsored in part by Bristol Myers Squibb and UCB. All content is chosen by RheumNow & its faculty.
Dr. John Cush RheumNow ( View Tweet)
Great work by @Yuz6Yusof
ANA positive and diagnosis , prediction tool to rule out/ in autoimmune pathology.
1-High interferon score.
2-FH autoimmune disease.
3- More criteria.
?Monogenic error of immune system , ?genome assessment .
@RheumNow , Daily recap
Nouf Al hemmadi ( View Tweet)
I vote for the ❤️
Several abstracts evaluated cardiovascular event prevalence and screening tools using ECHO, carotid ultrasound as current CV risk calculators are inadequate when assessing SLE CV risk. See my blog - just published @RheumNow
https://t.co/XLc0YHtJ0B https://t.co/oF0fXBRM6O
TheDaoIndex KDAO2011 ( View Tweet)
1-Can we prevent RA ? Vagotomy?
2-CV events in auto immune rheumatic disease pregnancies.
3-CVS vasculitis , challenges and role of Brain biopsy
And others……..
https://t.co/BX8bDSX1M3
@RheumNow , daily recap
#ACR23
Nouf Al hemmadi ( View Tweet)
Sunday recap @RheumNow
Very interesting abstracts:
https://t.co/BX8bDSX1M3
1- Fecal calprotectin in SpA population.
2-SLE; high or low steroids? Rapid or slow taper?
3-Molecular biomarkers for PAH in SLE.
4-Repeating imaging in ? Chronic back pain?
And others …….
Nouf Al hemmadi ( View Tweet)
#ACR23 Abstr#0784 Beyond renal response, let’s also focus on kidney function and Steroid-sparing effect. Post-hoc analysis of Phase 2 RCT showed Obinutuzumab preserved eGFR by 4ml/min/1.73m2/year with greater number of pts achieving <7.5mg/d of prednisolone bs PBO @RheumNowNews https://t.co/2hW74UF1ta
Md Yuzaiful Md Yusof ( View Tweet)
#ACR23 Abstr#0590 Graphical Abstract makes it easy to follow 👏. Data using EHR showed that in #SLE with Diabetes, SGLT2-i vs DPP4-i was associated with reduced risks of developing AKI, CKD, ESRD, hospitalisation, and heart failure. Genital infection is common @RheumNowNews https://t.co/Iku6LqoYVb
Md Yuzaiful Md Yusof ( View Tweet)
Cognitive function in PMR @DrTrishHarkins 71% cognitively impaired! Markedly higher than population level #ACR23 @RheumNow https://t.co/0KTnssktKz https://t.co/XyjFzioiqB
Richard Conway ( View Tweet)
20 years real-world data on disease burden, patient experience & unmet needs in Refractory #RheumatoidArthritis
▶️Higher glucocorticoid & opioid use
▶️Greater comorbidity & symptom burden
▶️More rheumatology visits
#ACR23
👉🏽https://t.co/CAUorjQbvN
by @KristinWipfler @Dr_K et al https://t.co/vx1aOZizfE
Dr Ai Lyn Tan DrAiLynTan ( View Tweet)
The Rheum Where It Happened! https://t.co/3gL5RLSNms
TheDaoIndex KDAO2011 ( View Tweet)
#ACR23 Abstr#0571 As there is a genetic predisposition to #SLE, can polygenic risk score distinguish SLE vs ANA+ with no disease? A study in European ancestry showed modest discrimination (AUC: 0.66). This showed other contributors are vital in SLE development @RheumNowNews https://t.co/qiFOlOxq5r
Md Yuzaiful Md Yusof ( View Tweet)