Knee Replacements Last 25 Years

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UK registry reports that greater than 80% of total knee replacements can last for 25 years.

The outcomes regarding the duration and durability of knee arthroplasties is sketchy, with many orthopedists projecting a 15 to 20 year survivial. Hence the need for an appraisal of the data.

NSAIDs May Impair Healing if Taken Nightly

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A new study in Scientific Reports suggest that circadian rhythms play an important role in wound healing, and that nonsteroidal anti-inflammatory drugs (NSAIDs) may be disruptive if taken at night given primary healing that occurs in a body at night. 

RheumNow Podcast- Knee Pain Knockout (1.10.20)

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Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com. The podcast covers: best therapies for dactylitis and enthesitis; we have a new knockout for knee pain in OA; and are you on the naughty or nice list when it comes to the new ACR-AF guidelines for arthritis? This and more. Tune in.

RheumNow Podcast - The Elusive Hand OA Problem (12.13.19)

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Dr. Jack Cush recaps the news and journal reports from the past week on RheumNow.com.

Short-term Benefit with Prednisolone in Hand Osteoarthritis

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Lancet reports that prednisolone 10 mg daily for 6 weeks can effectively control the pain of hand osteoarthritis (OA), according to results from the Hand Osteoarthritis Prednisolone Efficacy (HOPE) study.

This was a double-blind, randomized, placebo-controlled trial aimed to assess the short-term effects of prednisolone in painful hand OA and synovial inflammation. Patients were required to have hand OA and signs of inflammation in their distal and proximal interphalangeal (DIP/PIP) joints and > 4 DIP/PIP osteoarthritic nodes and at least one DIP/PIP joint with soft swelling/erythema or evidence of synovitis on power Doppler ultrasound. The primary endpoint was finger pain.

RheumNow Podcast – The Shoes Maketh the Doctor (10.25.19)

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Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

Voluntary Recall of Zantac by Sanofi/FDA

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Sanofi has initiated a voluntary recall of all Zantac OTC (over-the-counter) products in the United States. This includes Zantac 150®, Zantac 150® Cool Mint, and Zantac 75®.

Joint Injections: Are They Worth the Risk?

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Intra-articular injections of corticosteroids for relief of the pain of hip or knee osteoarthritis (OA) may have adverse long-term consequences, researchers suggested.

High Dose Statins Increase Odds of Osteoporosis

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It is unknown if inhibiting cholesterol synthesis (with statins) might influence sex-hormone production and therefore, the risk of osteoporosis. A new study shows that, in statin-treated individuals, the development of osteoporosis is statin dose-dependent.

RheumNow Podcast – When You’re Hot You’re Hot (10.11.19)

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Dr. Jack Cush delivers select commentary on select news and journal articles from the past week on RheumNow.com.

ASBMR Recommendations on Secondary Fracture Prevention

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The American Society for Bone and Mineral Research has developed multistakeholder consensus clinical recommendations for the prevention of secondary fractures for those aged 65 years and older after an initial hip or vertebral fracture.

Arthritis Foundation Releases First CBD Guidance for Adults With Arthritis

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As the leading organization for people with arthritis, the Arthritis Foundation has just released the first CBD guidance for adults with arthritis. CBD, or cannabidiol, a plant-based compound, has become popular among people with arthritis seeking to ease chronic joint pain.

RheumNow Podcast – Believe in Vitamin D or Rituximab? (9.20.19)

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Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

High-Dose Vitamin D: No Help for Bone Health

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Vitamin D might not be much help for strengthening bones among healthy adults without osteoporosis, Canadian researchers reported, even at doses far higher than recommended daily allowances.

In a clinical trial assessing three levels of daily vitamin D supplementation -- 400 IU, 4,000 IU, and 10,000 IU -- radial volumetric bone mineral density was significantly lower among those (ages 55-70) taking higher doses for 3 years, according to Steven Boyd, PhD, of the University of Calgary in Canada, and colleagues.

RheumNow Podcast – Upadacitinib FDA Approved for RA (8.23.19)

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Dr. Jack Cush reports on the news and journal reports from the past week on RheumNow.com, including: how your genetics may shape your microbiome; GERD as a risk factor for TMJ?; how can MDA-5+ dermatomyositis be any worse; new drug happenings; StillsNow.com; and more.

RheumNow Podcast – Antibiotics Increase RA Risk (8.16.19)

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Dr. Jack Cush reports the news and important journal articles from the past week on RheumNow.com.

Bisphosphonate Use Associated with Reduced Mortality

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The Journal of Bone and Mineral Research (JBMR) has published a report showing that a reduction in the rate of bone loss by nitrogen bisphosphonates was associated with a 40% lower mortality risk.

NSAIDs Mediate Cardiovascular Risk in OA

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NSAIDs have been linked to an increased risk of cardiovascular disease, but does this also hold for osteoarthritis (OA) patients.