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Krill Oil Effective in Knee Osteoarthritis

Jack Cush, MD

Krill oil supplements in knee osteoarthritis (OA) was shown to be superior to placebo in reducing knee pain, stiffness and function while increasing the omega-3 index.

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Best of

U.S. News & World Report’s 2022–23 Rheumatology Rankings

Jack Cush, MD

The Johns Hopkins Hospital has repeated its top rank among US Rheumatology centers - ranking #1 for the 18th year in a row, according to U.S. News & World Report’s 2022–23 Best Hospitals list released yesterday.

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Fever Pitch (7.15.2022)

Jack Cush, MD

Dr. Jack Cush reviews the new studies and drug approvals and new insights into febrile disorders from the past week on RheumNow.com

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Viscosupplementation Ineffective in Knee Osteoarthritis

Jack Cush, MD

The BMJ has published the results of a metanalysis showing strong conclusive evidence that viscosupplementation in knee osteoarthritis (kOA) has minimal effects on kOA pain, and also reveals strong evidence of an increased risk of serious adverse events. 

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What Worries You, Masters You (7.1.2022)

Jack Cush, MD

Dr. Jack Cush reviews recent news, regulatory and guideline updates from the past week on RheumNow.com.  Studies on methotrexate use, COVID vaccination, Supplements and vitamins, and arthrocentesis despite anticoagulation are discussed.

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Burnout Threatens the Rheumatology Workforce Conundrum

Jack Cush, MD

There is a shortage of rheumatologists in Canada and the recent 2020 Canadian Rheumatology Association (CRA) Workforce and Wellness study shows that the shortage may be compounded by rheumatologist burnout, especially among young and female physicians. 

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lumbar,spine,lbp,pain

Acute Inflammatory Responses Needed to Resolve Chronic Pain

Jack Cush, MD

Science Translational Medicine has published results of a Canadian study of low back pain (LBP) suggests that pain control by anti-inflammatory treatments might have negative effects on pain duration and may be counterproductive for long-term pain outcomes.

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Methotrexate Monitoring (5.13.2022)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. Bad news for digitial ulcers in Systemic sclerosis, Readmissions in Lupus and Thrombocytopenia in APL patients.

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Patient,instruction

Making You the Expert of You! (Smart Rules for Patients)

Jack Cush, MD

You’ve scheduled an appointment with your medical provider - how do you make the most of it? We've gathered these tips and suggestions to share with patients.

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Polygenic Risk Scores to Identfy Severe Knee and Hip Osteoarthritis

Jack Cush, MD

Prevention of knee and hip osteoarthritis would obviate considerable disability and future surgery.  We may be one step closer according to a prospective European GWAS study showing polygenic risk scores (PRSs) significantly associated with higher risks for knee and hip OA joint replacement.

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Heterozygous deficiency of Aggrecan (proteoglycan w/in cartilage) gene: manifests as inherited short stature, early-onset osteoarthritis, degenerative disc disease, osteochondritis dissecans, increasing joint pathology over time https://t.co/dQERowhrba https://t.co/q7a38FGEzb https://t.co/TPQmnGPoDw

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Dr. John Cush RheumNow ( View Tweet)
Heterozygous deficiency of Aggrecan (proteoglycan w/in cartilage) gene: manifests as inherited short stature, early-onset osteoarthritis, degenerative disc disease, osteochondritis dissecans, increasing joint pathology over time https://t.co/4iQdNL79oB https://t.co/qxStgE641v https://t.co/EHPJuIeQGt

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Dr. John Cush RheumNow ( View Tweet)
1 yr success of knee arthroplasty was drawn frm 20 studies (11 317 pts, 37 factors) suggests higher BMI was correlated w/ worse physical function. Physical function & OA severity assoc. w/ better function post-TKA https://t.co/jtDCeprUhd https://t.co/Tflw8VO5Kw

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Dr. John Cush RheumNow ( View Tweet)
Study of contoured foot orthoses vs sham shoe insoles in 1st MTP #OA pain: 87 pts completed 12 wk trial that showed no differences in 1st MTP walking pain or other 2nd outcomes. Hard orthoses are no more effective than flat sham insoles https://t.co/XAFWwpSjHm https://t.co/g5J9TbG2pQ

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Dr. John Cush RheumNow ( View Tweet)
Simultaneous Versus Staged Knee Arthoplasty? There are an estimated 900,000 knee replacements (TKR) performed in the U.S. every year. This number is up from 754,000 TKRs in 2017, according to the Agency for Healthcare Research and Quality. https://t.co/KuLEaI3r0d https://t.co/0q1RBsDwEM

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Dr. John Cush RheumNow ( View Tweet)
OA Initiative Study of 1212 knee OA pts (age 63 yrs), 73% walked for exercise. Walkers had signif. less New frequent knee pain (OR 0.6) & medial joint space narrowing (OR 0.8). Walking for exercise should be encouraged in knee OA pts. https://t.co/wCKjxwJ9EG

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Dr. John Cush RheumNow ( View Tweet)

Australian Bureau of Statistics 2017–2018 shows relative risk of undergoing knee replacement for OA increased with increasing BMI (Class 1- 3 obese females 55–64 yrs had 4.7 to 17.3 fold risk of KR. Same for obese Males (OR 3.4 - 5.8) more KR https://t.co/vcPmRgbzUH https://t.co/FrfTC9LNnR

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Dr. John Cush RheumNow ( View Tweet)
#POS1112 #EULAR2022 A crossover RCT assessed effect of weight- and non-weight bearing exercises on type 2 collagen in knee #osteoarthritis. Small rise in collagen turnover markers initially for 24hrs. Gradual rise later on was contributed to cardiovascular influence @RheumNow https://t.co/AOxdFNihPR
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Intra-articular morphine in knee arthritis. WHAT!? Not-surprisingly it doesn't work. Inferior to steroid and same as placebo. Still kudos to Haibel et al for answering this question @RheumNow #EULAR2022 OP0050 https://t.co/zjY36V9OCS https://t.co/j67omCQCxI

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Richard Conway RichardPAConway ( View Tweet)
Polygenic Risk Scores to Identfy Severe Knee and Hip Osteoarthritis This study identified genetic risk variants from genome-wide association analysis of OA patients to calculate PRSs associated with subsequent need for joint replacement surgery. https://t.co/ZhAiuFu8iw https://t.co/OsR6p9m2S9

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Dr. John Cush RheumNow ( View Tweet)
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