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ACR 2024 starts tomorrow. Here are a few previews of abstracts to be presented, along with my recommendations of sessions you don’t want to miss.
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Adult-onset Still's disease (AOSD) is systemic autoinflammatory disorder of unknown etiology. It is considered among the febrile autoinflammatory etiologies.
Antoni Chan MD (Prof)
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Recomendations for the management of Kawasaki’s disease. Cardiometabolic session, Bryce Binstadt @RheumNow #ACR24 https://t.co/KftwMDYzH1
Janet Pope
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#Baricitinib in refractory #myositis?
A ‘weak’ trial design comparing #Bari to #Bari Rx started 12 weeks later
in a small N =15
neat idea but NO answer
👇
looked like 👍 it worked
BUT
this is not the #RCT design that can show differences
#ACR24 @RheumNow abst#1731
@ACRheum
Dr. John Cush
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No Increase in Cardiovascular Events with JAK Inhibitors in IBD Patients
UMKC researchers have compared the use of JAK inhibitors versus tumor necrosis factor (TNF) blockers in inflammatory bowel disease (IBD) patients, but failed to see an increase in major adverse… https://t.co/XY0UVDTAI6 https://t.co/b09FB3niNP
Jiha Lee
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Multimorbidity reduces response to b/tsDMARDs in RA. We can make a difference by treating the whole person!
Amazing talk by Dr Iain McInned to wrap up #ACR24 #ReviewCourse.
@RheumNow https://t.co/NiaUXzt4nT
Mrinalini Dey
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⭐️Top tip from Dr Laura Carbone:
🦴Rule out hypophosphatasia before starting bisphosphonate or denosumab in patients with low ALP
#ACR24 @RheumNow
Brian Jaros, MD
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Pain in PsA = predictor of disability and QoL
TYK-2 inhibition lowered clinical pain outcomes and ALSO pain-associated biomarkers vs PBO
@RheumNow #ACR24 Abstract #2366 https://t.co/DAgmdmmTE0
Eric Dein
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Risk for atypical femoral fracture:
🚨Asian race - 4-6x higher risk
Duration of use is greater risk than older age
Higher risk when given for osteoporosis than cancer treatment
- Compare: osteonecrosis of jaw more common with cancer Rx
#ACR24 Review Course
@RheumNow https://t.co/V8cD5QWNGp
Dr. John Cush
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Weight Loss from Anti-Obesity Medications Prevents Gout
A population based study looked at the effect of the weight loss drug, Orlistat, in obese individuals. Compared to those untreated, orlistat over 1 year was associated with significant weight loss and significantly lower… https://t.co/P1iRjtHgHV https://t.co/MoohUKGvUn
Dr. John Cush
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Study of 237 SLE pts shows mood disorders, fibromyalgia & chronic damage were major determinants of poorer Quality of life in SLE. mean SLEDAI-2k was 1.7, 29% had FM; 44% had chronic damage. https://t.co/JHzmleVMIK https://t.co/Sqk9K6oA7M
TheDaoIndex
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Don’t use ‘biopsy-proven’ to label sarcoidosis; use ‘biopsy supported’ as there are many causes of granulomatous inflammation. It’s happened to one of my pts who was diagnosed with “biopsy-proven” sarcoidosis - she actually had CVID with GLILD. #ACRReview #ACR24 https://t.co/it41va1K6g
Antoni Chan MD (Prof)
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Summary of treatments in psoriatic arthritis #PsA @RheumNow #ACR24 https://t.co/EybzRCPLtA
Dr. John Cush
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What is Osteoarthritis? A downloadable patient education page from JAMA. https://t.co/gocsQizJUh https://t.co/4bBuNUAYlR
Dr. John Cush
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Survey of 779 RA pts in the National Rheumatoid Arthritis Society. Respondents were 95% Caucasian in their 50s with menopause in their 40s. 80% responded that their arthritis was worse during the menopause with 10% being much worse. https://t.co/NqZXK1lLQe https://t.co/k59HD5bKrd
Dr. John Cush
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PAs in rheumatology report higher job satisfaction and lower burnout rates compared to PAs. Study of 430 PAs practicing in rheumatology. median age = 39 yrs, 85% female. They are 79%office-based practices, more likely to Tx older pts & engage in telemedicine(62.5%)… https://t.co/Zti5YMBo8o https://t.co/2XaWjythR1
Dr. John Cush
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Dysregulated overproduction of angiopoietin-like protein 4 (ANGPTL4) may be involved in RA pathogenesis. Markedly elevated in RA tissues & is a regulator of angiogenesis & inflammation. Anti-ANGPTL4 inhibited Dz in mice and fibroblast-like synoviocyte migration &… https://t.co/aOpnxicQSs https://t.co/1BC8CxwF6V
Dr. John Cush
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Dr. Quotes (11.8.2024)
Dr. Jack Cush reviews the news and journal reports from this past week from https://t.co/V10S4oWdi3.
https://t.co/NEXFg3Mp5G https://t.co/tUkGSgm6O7
Dr. John Cush
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Biosimilar Slow Growth in USA
A recent Forbes article, "Biosimilars Are Making Inroads In U.S., But It’s Still A Bumpy Ride", reviews the current state and reasons for slowish uptake of these significant cost-savings alternatives to biologic therapy in treating cancer and… https://t.co/yO3tUVk2jj https://t.co/ft6gqpnWMx
Dr. John Cush
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Early RA Journey - Patient Perspectives and Uncertainties
Canadian early RA (ERA) patients were interviewd to depict their perspectives from onset and diagnosis to referral and care. This report highlights the importance of patient pain and primary care physician (PCP) intake… https://t.co/gwNL7iZIT5 https://t.co/SL0Jw0H8f6
