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The American College of Rheumatology has published a draft guidance on the use of COVID-19 vaccination in rheumatic disease and musculoskeletal disease patients, based on the efforts of the North American Task force. The document provides guidance to rheumatology providers on the use of the COVID-19 vaccine and the associated management of RMD patients around the time of vaccination. Here is a summary of the recommendations.
French review of 41 TRAPS pts w/ amyloidosis AA. AA dx preceded TRAPS in 96% of cases, 47% needed renal replacement therapy and 14% died at 23 most F/U. 19 pts took biologics, 10 improved, 7 stabilized, 4 worsened. AA pts should be screened for TRAPS https://t.co/tONNSRCoOU
122 Adult onset Still's disease pts followed a median of 12 mos shows 21% with >=1 relapses. The cumulative relapse rate was 29% at 36 mos. Relapses increased w intensive Rx (OR 6.8) & MAS (OR 4.0)."Intensive" refers to steroids plus DMARDs - not biologics https://t.co/BRKi5sUQQZ
QD Clinic: PFAPA Syndrome Recurrent Fevers, Stomatitis, Lymphadenopathy ? https://t.co/uMBk8e2wJO https://t.co/02ZMjRmOuU
QD Clinic - PFAPA Syndrome Recurrent Fevers, Stomatitis, Lymphadenopathy ? https://t.co/uMBk8e2wJO https://t.co/LIs02svEDB
Dr. Shenoi Suspect autoinflammatory Dz: patterned fevers MSK and skin involvement Serositis Other - aphthous ulcers, CNS (stroke, basal ganglia calcification,) ILD, LN, lipodystrophy) ethnicity (FMF or Mediterranean) Family Hx -- Testing options! #RWCS2021 @RheumNow @RWCSmtg https://t.co/DZk4hsxbk4
Dr. Shenoi reviews PFAPA (Periodic Fever, Aphthous ulcers, Pharyngitis, and Adenitis) in children and adults - and the potential for associated genes/ Bechet's disease spectrum. #RWCS2021 #RWCS @RWCSmtg @RheumNow https://t.co/AS4qVqUsFY
PFAPA does not have a genetic dx (yet). But she's sure increase in IL - 12 p70, this making apremilast and ustekinumab potential therapy for difficult cases. @RWCSmtg https://t.co/gdz7d5KCrm
PFAPA may be part of a spectrum the includes Behcets @rwcs https://t.co/wmX76bFPX2
PFAPA (aka Marshall syndrome) also occurs in adults @RWCSmtg https://t.co/52NVpKGCzP
Dr. Susan Shenoy @rwcs shows discovery of autoinflammatory diseases began w MEFV genes (FMF) in 1997, followed by genes for TRAPS and HIDS in 1999. @ https://t.co/sG4BlK1zhR
Not just Juvenile: Adult Onset Still's Disease Complicated by Macrophage Activation Syndrome RWCS 2021 Poster Session by Dr. Eric Seronick, UC-Irvine https://t.co/p9DsTu8kBK
QD Clinic - Fever by the Numbers Diagnosis of Periodic Fever by Fever Duration https://t.co/q3ZmJLrgOO
Defects in NLRC4 inflammasome can drive IL 18 production in systemic JIA. @RWCSmtg https://t.co/ffzODTXd52
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