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Fever, FROST, & Pericarditis (12.16.2022)

d Jack Cush, MD

Dr. Jack Frost reviews the news, and journal articles from the past week on RheumNow and ends with an audience question on "Macro-CK".

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covid vaccine needle vaccination

COVID-19 Vaccine Responses in Rheumatic Disease Patients

d Jack Cush, MD

Nature Reviews Rheumatology features a review of three notable papers that address the impact of SARS-CoV-2 vaccination on people with inflammatory rheumatic disease. 

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ild.jpg

JAK Inhibitor Potential in Systemic Sclerosis-Associated ILD

d Jack Cush, MD

The occurrence of interstitial lung disease (ILD) in Systemic sclerosis portends serious morbid and mortal outcomes for those affected. This review examines the available clinical literature on the potential benefits and outcomes of JAK inhibitor use in SSc=ILD.

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Vegetarian diet food nutrition

ACR New Guidelines on Integrative Approach to RA

d ACR

The American College of Rheumatology (ACR) released a summary of its new guideline for Exercise, Rehabilitation, Diet and Additional Integrative Interventions for Rheumatoid Arthritis.

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73-87% of autoimmune (RA, SLE, UCTD, APL) pts used HCQ during pregnancy. HCQ significantly reduced pre-eclampsia (20% vs 9%), early-onset pre-eclampsia (8% vs 2.5%), 2nd/3rd trimester pregnancy loss (3% vs. 0.6%) https://t.co/CF5ivHeCmY https://t.co/CYqaCCuZJz

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Fever, FROST, & Pericarditis Dr. Jack Frost reviews the news, and journal articles from the past week on RheumNow and ends with an audience question on "Macro-CK. https://t.co/IFxocGkOxJ https://t.co/OzoS248ZRK

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Dr. John Cush RheumNow ( View Tweet)

Review of the Rheumatic causes of Pericarditis and their management. Causes: SLE, RA, MCTD, Myositis, EGPA, GPA, IgG4-rel Dz, FMF, TRAPS, CAPS, AOSD, JIA, Sarcoidosis, Kawasakis, GCA, Takayasu's https://t.co/MQmkUe4Yey https://t.co/FSfrznoeBe

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JAK Inhibitor Potential in Systemic Sclerosis-Associated ILD The occurrence of interstitial lung disease (ILD) in Systemic sclerosis portends serious morbid and mortal outcomes for those affected. https://t.co/LWHKO0gRu4 https://t.co/i2IOLcAgt3

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New download available-GCA and PMR New Drugs https://t.co/7Y4g6zvTQx. https://t.co/ZfVO0SRVuL

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CXCL5 Therapy in Lupus? A new study has shown that restoring the balance of a protein in blood may be a promising treatment option for systemic lupus erythematosus, or lupus, an incurable autoimmune disease. https://t.co/B82Xq5FFNJ. https://t.co/ba2nlFuDsI

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Low dose steroids can negatively impact bone health Dr. Janet Pope discusses abstract L01 presented at ACR22. https://t.co/eBGMza9tWE https://t.co/wACnLTxATu

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The First Head to Head trial in Axial SpA Dr.Gensler discusses abstract L15 presented at #ACR22. L15: Effect of Secukinumab versus Adalimumab Biosimilar on Radiographic Progression in Patients with Radiographic AxSpA: A Randomized Phase IIIb Study https://t.co/RgwKRJwgoS https://t.co/6LxOURICiE

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Marginal Benefit with Diet and Exercise in Obese Knee Osteoarthritis Patients The easiest intervention for knee osteoarthritis (diet and exercise) is also the most difficult for many patients; but do these work? https://t.co/s4Gzmh2gGZ https://t.co/aZORTMtCvs

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Get the Skinny on Bimekizumab in PsA Dr. Janet Pope discusses abstract presented at #ACR22. https://t.co/FKFARxQ2fa https://t.co/wSyXeSHII3

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During 2021–22 FLU season, 6% of hosp pedi-influenza pts had SARS-CoV-2 coinfection; these required more respiratory support. Risk of influenza death augmented by not recv vaccination (flu or covid), no antiviral Rx, comorbidities & coinfx w/COVID https://t.co/bfjeClHflW https://t.co/YTOEnNSQQN

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Lupus Research Alliance announced 2022 Distinguished Innovator Award recipients: - Hongbo Chi, PhD, Exploring Metabolism of Follicular Helper T Cells & Lupus Progression - Joseph Craft, MD: Processes Enabling T Cells to Be Destructive in Lupus Nephritis https://t.co/yI2NlCHaBi https://t.co/fevBTkaxCY

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#OA phenotypes by SF cell status - Activated: hi T-cell, low mono–macrop-PMN activated; 70% improved - Lymphoid: hi PMN, low lymph & mono, low activ, lower pain - Myeloid: hi NK & mono, low T-cell & activat - Aggressive: hi lymph/macr/NK/PMN;39%improve -https://t.co/3DXPoDE5Pm https://t.co/VRJkscAm5a

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Comorbidities in Axial Spondyloarthritis Dr. Antoni Chan discusses Abstract 1609 at ACR22 Convergence. https://t.co/dCLlgiGV9K https://t.co/a4iI1q3zZC

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Will a vegetarian diet and exercise actually help RA disease activity? https://t.co/NI6xmhN0sO https://t.co/7IlQWkXkE1

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A&R: Climate Emergency and the Health of Our Patients - A public health crisis that will affect Rheum pts - climate factors can worsen Dz - Pollution causes autoimmunity - Climates worse effects on the vulnerable - Advocacy solutions research are needed https://t.co/JJufiImhND

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