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Biomarker Predicts Survival in Autoimmune Lung Disease

MedPage Today Jan 02, 2024

One major subgroup of patients with interstitial lung disease (ILD) arising from polymyositis/dermatomyositis (PM/DM) survived significantly longer when serum levels of interferon-λ3 were relatively low, researchers found.

Best of 2023: New ACR RA-ILD Treatment Guidelines – What Were They Smoking!? Rheumatoid arthritis related interstitial lung disease (RA-ILD) is common, with symptomatic RA-ILD affecting approximately 8% of RA patients. https://t.co/6RFBjVkmXj https://t.co/Qvquu7ruKY

Best of 2023: New ACR RA-ILD Treatment Guidelines – What Were They Smoking!? | …

AutoAbs in poly/dermatomyositis - ANA+ 50% to 80%, but not helpful in Dx. Look for MSA Abs - espec antisynthetase ABs (anti-Jo-1), but also newer Abs: MDA-5, TIFF-1 gamma, NXP-2 (to be discussed #RNL24 Dr. Christopher-Stine) https://t.co/l46JHMWJby https://t.co/rZco5BMUJ5 https://t.co/2K9bidzLpt

Global temporal trends in MSK disorders in women of childbearing age increasing in138 countries, 24 decreasing & 42 w. flat trends. In 2019, the prevalence was 354 million w/ India, with China, USA, Indonesia & Brazil highest w/ 51% of global prevalence https://t.co/8nn4lTtNU2 https://t.co/BdkR3aXsZO

Global, regional and national temporal trends in prevalence for musculoskeletal…

Best of 2023: Treatment and Management of Neuropsychiatric Lupus On the first day of ACR State of the Art conference in Orlando, Florida, Dr. Michelle Petri reviewed the treatment and management of neuropsychiatric lupus. https://t.co/0MXAtkDUmQ https://t.co/ZYuLniETnP

Best of 2023: Treatment and Management of Neuropsychiatric Lupus | RheumNow

Best of 2023: Does Biologic Treatment in Psoriasis Reduce the Risk of Psoriatic Arthritis? https://t.co/9xn7lvxPiG https://t.co/PFYUISEKLe

Best of 2023: Does Biologic Treatment in Psoriasis Reduce the Risk of Psoriatic…

FDA Approves the first Actemra biosimilar- called tocilizumab-bavi (Tofidence) or BIIB800 (during development). This IV FORMULATION is approved for use in active RA, polyarticular JIA and systemic JIA. https://t.co/XdQ3D2McTF https://t.co/wnusToyZTG https://t.co/w8ooCCGrI0…

Could Methotrexate Work in Hand Osteoarthritis? Lancet reports the results of the METHODS study from Australia where hand osteoarthritis (HOA) patients benefitted from 6 months of methotrexate (MTX) - as long as there was MRI synovitis! https://t.co/TnvhGUiWuw https://t.co/FfnC63nBSa

Could Methotrexate Work in Hand Osteoarthritis? | RheumNow

Full Read review of #PMR in Lancet: - Start @ 12·5–25mg prednisone qd - Remission in most but, relapses in 40–60% - Onset sudden; AM stiffness predominates; Shoulders>Pelvic ~50% have distal MSK Sxs - US: look for B/L sub-acromial/deltoid bursitis https://t.co/NwrbdMMdLU https://t.co/eRls0fLMJs

Polymyalgia rheumatica

Gout Flare Prophylaxis - Colchicine or NSAIDs? A new study suggests that colchicine, more so than non-steroidal anti-inflammatory drug (NSAID) prophylaxis, may increase the odds of adverse events, when initiating allopurinol for gout. https://t.co/mZZxTIUeQq https://t.co/43COjhNXUf

Gout Flare Prophylaxis - Colchicine or NSAIDs? | RheumNow

#RNL2023 Dr. Stanley Cohen: possible adverse effects of JAKi -Herpes zoster, other infections -Malignancy -Occasional cytopenias -LFTs (with DMARDs) -Incr Cr or CPK -Acne -Incr lipids -GI perf -VTE Which do you counsel with your patients? https://t.co/wOZh9qGQZD https://t.co/ODNcDHp1iU

https://bit.ly/3RDmXcd

AOSD: Young vs. Elderly Onset AOSD is an autoinflammatory condition characterized by fevers, arthritis, & rash. It is considered an orphan disease because of its low prevalence - reported anywhere between 16 to 40 per ten million. https://t.co/gvbPkeq2sH https://t.co/J25U6rWNTy

AOSD: Young vs. Elderly Onset | RheumNow

JAMA: cutaneous hallmarks of dermatomyositis. Printable Patient education overview. https://t.co/S7MaAz6fX2 https://t.co/5ETcQRz8Fd

Dermatomyositis

SGLT2 Inhibitors Reduce Gout Flares and CV Events. A cohort analysis shows that gout patients initiating sodium–glucose cotransporter-2 inhibitors (SGLT2is) had lower serum urate levels and fewer gouty flares requiring ED visits or hospitalizations. https://t.co/laOh4CsZ8Z https://t.co/6oas9AWc8j

SGLT2 Inhibitors Reduce Gout Flares and CV Events | RheumNow

Are you up-to-date with the relationship between SpA, its comorbidities, and how it impacts patients? Review this update showcasing a present overview of this topic. Sponsored by Novartis Medical Affairs. https://t.co/zirCeZ0Fgh https://t.co/HIwVNoV94H

SpA and Comorbidities: The Flip Side | RheumNow

Rheumatoid vasculitis (RV) metanalysis: RV decreased from 9.1 (1988-2000) to 3.9 (2001-2010) per million. RV risk increased w/ smoking, disease duration, seropositivity, males, HLA-DRB104, HLA-C3. Common: skin (65–88%), CNS(35–63%), cardiac (33%) https://t.co/gBxd9EIvo2 https://t.co/NFMSkeAq5d

Rheumatoid vasculitis in 2023: Changes and challenges since the biologics era

A double-blind, sham-controlled RCT of auricular vagus nerve stimulation (VNS) showed NO meaningful improvement in 101 RA completers. @week 12, ACR20 was 25% for VNS vs 27% for sham (NS). Also NS was change in DAS28-CRP (–0.95 vs –0.66)(p 0.06) https://t.co/n4e564a3gN https://t.co/mnVliEuafK

A Randomized, Double‐Blind, Sham‐Controlled, Clinical Trial of Auricular Vagus …

Plantar Fasciitis study of 180 PF patients shows no clinically meaningful difference between pts treated with patient advice plus heel cup alone (PA) versus PA and lower limb exercise (PAX) versus PAX plus corticosteroid injection (PAXI) https://t.co/X5Q1MlmkzW https://t.co/NtbLQv6b2q

Does a corticosteroid injection plus exercise or exercise alone add to the effe…

RheumNow Live 2024 is nearly here! Among our 25 speakers, Dr. Weber will cover Cardio-Rheumatology Clinic - Identifying CV Risks. Dr. Guma will cover Nutrition in RA. Dr. El Gabalaway will cover the Prevention of RA, all in a session on Success in RA. https://t.co/5kq9KReEsJ https://t.co/L2GiR8Upqn

RN Live - RheumNow

AOSD: Young vs. Elderly Onset | RheumNow

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Biomarker Predicts Survival in Autoimmune Lung Disease

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