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Gender equity in academic rheumatology
Although almost half of our specialist rheumatology physician workforce is now women, gender inequity in career progression within academic rheumatology is a persistent problem. A recent analysis of the US rheumatology workforce showed that although women were well represented in rheumatology program director and division director leadership roles, women academics were less likely to be full or associate professors, had fewer publications, and received fewer NIH grants.
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12 mos. serial study of 71 pts with gout found 42% with at least 1 gout flare (median=2) over 12 mos. US eval. showed "Flare" pts had signif more MSU deposits (6.7 vs 2.9) & power Doppler (3.73 vs 0.82)vs controls. By US- were 17-29% more likely to flare. https://t.co/icDyNEsCa6 https://t.co/86pgBzG9MC
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Dr. John Cush RheumNow ( View Tweet)
Lillys IL-23 inhibitor (Mirakizumab) has suffered a minor setback receiving a "complete response letter" from the FDA regarding MIRA application (BLA) for use in ulcerative colitis. The CRL hold up is related to the manufacturing issues (not data/safety) https://t.co/Xs93pFNFAp https://t.co/vlVP8qiqGr
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Dr. John Cush RheumNow ( View Tweet)
Pain and Opioid Updates
The CDC and FDA provided new updates on the scope of pain in the USA and guidance on the use of opioids.
https://t.co/jjN9zvX7rV https://t.co/kY3kX1S8vq
Links:
Dr. John Cush RheumNow ( View Tweet)
Retrospective study of 147 THA and TKA pts w/ acute/chronic complaint - 39 pts Dx w/ prosthetic joint infection (PJI). Absolute numbers of neutrophils (PMNs) best predicted PJI (THA > 3,600 PMN/µl; TKA >2,000 PMN/µl (sensitivity 97%; specificity 93.5%) https://t.co/pxKcsTT6tn https://t.co/IQZ0DSUxwc
Links:
Dr. John Cush RheumNow ( View Tweet)
Best Treatments for Immune Checkpoint Inhibitor-associated Arthritis
A retrospective study of cancer patients who developed ICI-IA shows that biologic DMARDs were more effective than csDMARDs in rapid control of arthritis.
https://t.co/EQjSgav0by https://t.co/CZ0IqR3UXM
Links:
Dr. John Cush RheumNow ( View Tweet)
Clinical Profile of RA-associated Interstitial Lung Disease
A prospective, cross-sectional analysis of patients with rheumatoid arthritis (RA) shows those with interstitial lung disease (ILD) tend to be older, obese and have a smoking history.
https://t.co/FazEGcHh5H https://t.co/oh6oIpj21k
Links:
Dr. John Cush RheumNow ( View Tweet)
4/18 Tuesday Night Rheumatology: Private Practice & Academia
Our panelists will address the big questions of: "How do I choose between private practice and academia?" and "How do I advance in my career?"
Sign up for this session and all sessions here:
https://t.co/TrMpNmHpj3 https://t.co/3vIwxK0CUU
Links:
Dr. John Cush RheumNow ( View Tweet)
"If you want to go fast, go alone. If you want to go far, go together." -(African proverb)
Dr. John Cush RheumNow ( View Tweet)
COVID had a significant effect on mental health of inflammatory rheumatic Dz (IRDs) pts. UK NHS survey of 639 IRD (70% RA, 16% PsA) saw 40% w/ mod/severe pandemic impact on physical & mental health; 29% w/ depression, 22% anxiety; affecting Women>males https://t.co/kcAwa2Lks2 https://t.co/R6tk2aOrGQ
Links:
Dr. John Cush RheumNow ( View Tweet)
Japanese cohort study shows Lung cancer is more common in males w/ elder-onset dermatomyositis - risk increased by Smoking, anti-TIF1-γ-Abs and elevated MLR (monocyte to lymphocyte ratio) https://t.co/C7BTAV5gCj https://t.co/YGq6sUbLOh
Links:
Dr. John Cush RheumNow ( View Tweet)
Retrospective study of 42 pts w/ cocaine-induced midline or systemic vasculitis; Current cocaine use common (20/23 + urine tox, including pts who prev. deniedcocaine). Found: septal perfs (75%), oronasal fistula(15%), less(27%) systemic Sxs, 56% PR3-ANCA+https://t.co/tCt8l6Neb3 https://t.co/LzEpP5Z2fT
Links:
Dr. John Cush RheumNow ( View Tweet)
Antiphospholipid Antibodies With Incident Cardiovascular Events
Are antiphospholipid antibodies (aPL) associated with atherosclerotic cardiovascular (ASCVD) event risk?
https://t.co/5KhXWgF4RA https://t.co/BjIINjM1ml
Links:
Dr. John Cush RheumNow ( View Tweet)
Probiotic strain Ligilactobacillus salivarius studied in gout (as it metabolizes purines). 30 pts w/ hyperuricemia & recurrent gout were given L. salivarius or allopurinol for 6 mos. Probiotic group had less gout attacks (5/15) than controls (13/15). https://t.co/YYq4zHEPoB https://t.co/aitjaTgx8B
Links:
Dr. John Cush RheumNow ( View Tweet)
This past Tuesday Night Rheumatology was focused on contracts and contract negotiations.
This highly informative discussion featured:
Gwenesta B. Melton, MD, FACR ( @gwenesta_melton )
Andrea Liberatore, JD
Kathryn H. Dao, MD ( @KDAO2011 )
https://t.co/fK7JkQQzRZ https://t.co/aDHA5COq2V
Links:
Dr. John Cush RheumNow ( View Tweet)
RA Patients on Biologics and tsDMARDs are still High Risk
A new Swedish ARTIS registry study of key safety outcomes in RA patients receiving either targeted synthetic or b/ts DMARDs, including JAKi, has been updated and affirms previously held risks.
https://t.co/mqfP4deGJv https://t.co/m43GSRlrct
Links:
Dr. John Cush RheumNow ( View Tweet)
Best Treatments for Immune Checkpoint Inhibitor-associated Arthritis
A retrospective study of cancer patients who developed ICI-IA shows that biologic DMARDs were more effective than csDMARDs in rapid control of arthritis.
https://t.co/O5bMpwwM8Z https://t.co/H27RSA3oMt
Links:
Dr. John Cush RheumNow ( View Tweet)
Mentoring is Personal
Dr. Una Makris ( @UnaMakris ) shares a few lessons learned about being both a mentor and mentee.
https://t.co/6UyHlre0hL https://t.co/iGS4LDcnO0
Links:
Dr. John Cush RheumNow ( View Tweet)
Clinical Profile of RA-associated Interstitial Lung Disease
A prospective, cross-sectional analysis of patients with rheumatoid arthritis (RA) shows those with interstitial lung disease (ILD) tend to be older, obese and have a smoking history.
https://t.co/Khe9jV1jGa https://t.co/WejiaxolQP
Links:
Dr. John Cush RheumNow ( View Tweet)
Join us April 18 for: Private Practice & Academia
In this session, our panelists will address the big questions of: "How do I choose between private practice and academia?" and "How do I advance in my career?".
https://t.co/BrWG57mRRG https://t.co/A0pzEvJ3cu
Links:
Dr. John Cush RheumNow ( View Tweet)


