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psoriasis,arms,pain

Towards More Uniform Methotrexate Dosing in Psoriasis

d MedPage Today

With overwhelming support from some 200 experts worldwide, dosing of methotrexate (MTX) for psoriasis should start at 15 mg/week for most adults, though lower in those considered "vulnerable" and in children, according to a new consensus statement.

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PsA All the Way – Unmet Needs

d Jack Cush, MD

Throughout the month of April 2022, RheumNow is introducing a new approach to education and information sharing – a campaign devoted to a single disease. Our first campaign is entitled PsA All the Way: RheumNow will escalate awareness on this topic, its unmet needs, clarify advances and discuss key advances and modern disease management. We're featuring guest bloggers, hosting Tuesday Night Rheumatology, posting slides and videos, and much more dedicated to PsA.

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cancer, melanoma, metastatic, cell

Increased Cancer Risk with Autoimmune Disorders

d Jack Cush, MD

The incidence and mortality of cancer among autoimmune diseases (AID) was studied in a large Chinese cohort, demonstrating that while onset time and risks vary, there is an increased risk of malignancy in AID.

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Heart Risks Elevated in RA Patients Despite Biologic Tx

d MedPage Today

Hopes that biologic drugs for rheumatoid arthritis (RA) would cancel the extra cardiovascular risks normally seen with the disease dimmed a little in the face of findings from a population-based study from Scandinavia.

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The Effect of Socioeconomic Status on Lupus Outcomes

d Jack Cush, MD

Socioeconomic status (SES) often associates with poorer outcomes in systemic lupus erythematosus (SLE) patients; and a current study suggests this is unrelated to healthcare access issues.

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RheumNow's PsA Campaign with enhanced coverage of Psoriatic Disease is sponsored by Janssen. All content is chosen by RheumNow + its faculty. #PsAlways https://t.co/sjwVaNjK6x
Dr. John Cush RheumNow ( View Tweet)
Systematic lit review of 5694 CTD pts (SLE, RA, IIM, SSc) admitted to the ICU shows overall risk of mortality was 33%. ICU admits mainly for sepsis (43%), flares(40%). Mortality risk was 70% in IIM, 40% SSc, 35% SLE subgroup, 20% RA. https://t.co/ubVujkLCNy https://t.co/nnJdO36imK

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Dr. John Cush RheumNow ( View Tweet)
Retrospective cohort hospital study of 228 children with MIS-C; 215 patients (median age 8 yrs, 63% boys) shows that orticosteroid monotherapy is a reasonable management option for a subset of patients with MIS-C, particularly those with mild disease https://t.co/HLSR5zOseU https://t.co/5z7I9SVcxI

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Dr. John Cush RheumNow ( View Tweet)
#PsA Biologic initiation was associated with a SMALL drop in NSAIDs (51.1 to 42.5%); glucocorticoids (57.4 to 46.9%) and opioids (38.1 to 33.8%) (Initial vs 12 mos later). Pain Rx use study in 5681 PsA, 2180 AS, & 34,047 RA pts #PsAlways https://t.co/wyrT9CVNq8 https://t.co/8vl7e2a63n

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Dr. John Cush RheumNow ( View Tweet)
Korean study shows #RA is assoc w/ a risk of primary open-angle glaucoma, esp within 2 yrs of Dx & if >75 yrs. Study of 2049 older incident RA pts; POAG risk higher in RA than the matched controls (HR 1.44), 1st 2 yrs (HR 1.83), >75 yrs (HR 2.12) https://t.co/IvPw5InSis https://t.co/dkrK6RvRKE

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Dr. John Cush RheumNow ( View Tweet)
Danish study of opioids in psoriasis (n 4016), PsA (847) & controls (3490). Opioid Use within 12 months seen in 9% general population, 14.2% psoriasis without PsA, & 22.7% concomitant PsA pts. Joint pain incr analgesic use (OR 3.72) #PsAlways https://t.co/WKrA8sChyN https://t.co/9FLq4mKz7V

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Dr. John Cush RheumNow ( View Tweet)
The Effect of Socioeconomic Status on Lupus Outcomes Socioeconomic status (SES) often associates with poorer outcomes in systemic lupus erythematosus (SLE) patients; and a current study suggests this is unrelated to healthcare access issues. https://t.co/J1BMlsakGN https://t.co/BNhCN89Pqv

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Dr. John Cush RheumNow ( View Tweet)
Japanese study using Mendelian randomization (MR) analysis of the association between coffee consumption, gout & uric acid levels - showing coffee consumption can causally reduce gout risk (OR = 0.50), independent of SUA levels https://t.co/ymovYj5y40 https://t.co/uI7OqY9FcU

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Dr. John Cush RheumNow ( View Tweet)
Study of 1899 ankylosing spondylitis pts(10 RCTs) shows TNFi resp can be predicted - 34% had major resp vs 34% w/ no resp @ wk12. A major resp increased w/ higher CRP, Pt Global & BASDAI-Q2 score & decr w/ higher BMI & BASFI https://t.co/DrT7EVcZi0 https://t.co/CcFicTM0Mo

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Dr. John Cush RheumNow ( View Tweet)
Your Lupus Questions from RNL 2022 Rheumatologists questions for Dr. Jack Cush QD Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022 https://t.co/845D5KfUzY https://t.co/RtKopcTfiY

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Dr. John Cush RheumNow ( View Tweet)
Baricitinib Efficacy in Alopecia Areata https://t.co/6jYX5sPW44 https://t.co/Hvalig6U7V

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Dr. John Cush RheumNow ( View Tweet)
Your Rheumatoid Questions from RNL 2022 Rheumatologists questions for Dr. Jack Cush QD Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022 https://t.co/sHBMKNvoXQ https://t.co/jcQgOIz7xt

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Dr. John Cush RheumNow ( View Tweet)
JAMA reports another study showing safety of COVID-19 vaccination during pregnancy with no incr in adverse pregnancy outcomes. Scand study of 157,521 births - 0.7%, 8.3%, 9.1% of were vaxD during 1st, 2nd, 3rd trimesters https://t.co/dZuabwr1Sf https://t.co/CtzMoEV1Ee

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Dr. John Cush RheumNow ( View Tweet)
Canadian population study shows that mRNA COVID-19 vaccination DURING 2nd &3rd trimester of pregnancy did not increase rate of adverse peripartum outcomes (vs no vax or vax post-Preg). Comparison of 97 590 Preg vs 44 815 non-preg https://t.co/n7nWcoLw4S https://t.co/uiVOg5A1S8

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Dr. John Cush RheumNow ( View Tweet)
Free Teaching PDF on "What is Rheumatoid Arthritis" from JAMA https://t.co/EGdq1jbjzJ

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Dr. John Cush RheumNow ( View Tweet)

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