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Steroids in Lupus Nephritis: No Free Lunch
Today I'm here to talk with you about steroids in lupus nephritis. The impetus for this is the 2024 ACR guideline for the management of lupus nephritis.
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Biologics in Pregnancy Patients With Autoimmune Disease
A large cohort, claims data study shows that among pregnant women receiving biologic therapies for autoimmune conditions, 72% continued their biologics pregnancy, more so among inflammatory bowel disease (IBD) patients than those with rheumatoid arthritis (RA), psoriasis (PsO) or psoriatic arthri
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Panacea of Prednisone & Cannabis (5.16.2025)
Dr. Jack Cush reviews the news, journal and regulatory reports from this week on RheumNow.com. Interesting trends and results with prednisone in lupus, cannabis in RA and opioid deaths too!
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Lupus QD Clinic - Rhupus
dsDNA+ SLE Plus CCP+ RA = Rhupus
https://t.co/lyV7fgd1vp https://t.co/IKkS0enQH9
Dr. John Cush RheumNow ( View Tweet)
Periprosthetic femoral Fx (PPFF): metanalysis of 36 studies found PPFF risk factors: Uncemented stems (OR 3.36), major teaching hosp (2.0), female (1.6), obesity (1.4), Hi comorbidity(1.4), RA (1.89), (1.67), revised THR (2.6). OA = protective (0.51) https://t.co/y2BpH8LUb6 https://t.co/hX2lcjI4Kg
Dr. John Cush RheumNow ( View Tweet)
Lupus in an empty house
The full house immunofluorescence pattern is the classic histopathologic finding of lupus and lupus nephritis. Glomerular deposits staining for IgG, IgA, IgM, C3 and C1q can help confirm a suspected diagnosis of systemic lupus erythematosus (SLE). This https://t.co/DQWwRJmdqM
Dr. John Cush RheumNow ( View Tweet)
Assessing and Treating CV Risk Increases in Systemic Lupus
For nearly 50 years, the heightened CVD risk in SLE patients has been acknowledged since Urowitz et al.'s 1976 study on lupus mortality. Research consistently shows SLE patients have a 2-10 times higher CVD risk than https://t.co/P1AdxHkiQi
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Emulation trials in SLE: Real or Fake?
Recently a landmark paper was published in A&R studying the results of an emulation trial. My colleagues and I were able to write an editorial on this paper and describe emulation trials.
https://t.co/0ulYG5xz0J https://t.co/y2jo2SSH83
Dr. John Cush RheumNow ( View Tweet)
SLE Perspectives: Past, Present, Future
https://t.co/ggYmVvEtZx https://t.co/VriDjAEcl5
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Comparing EULAR (2025) and ACR (2020) Guidelines on Safety of Lupus Medications in Pregnancy Attendees at the 2025 RheumaPreg meeting were excited to discuss the newly released EULAR recommendations for use of antirheumatic drugs in reproduction, pregnancy, and lactation. https://t.co/csd0FE08ZO
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Risk Factors for Knee Osteoarthritis
New research from the University of Sydney reveals that obesity, having a knee injury and occupational risks such as shift work and lifting heavy loads are primary causes of knee osteoarthritis.
https://t.co/Kc686Zc8Xa https://t.co/ANyiE2pIxo
Dr. John Cush RheumNow ( View Tweet)
New Steroid Rules in Lupus? Let’s Talk.
Dr. Michelle Petri breaks down the latest strategies to minimize steroid exposure while managing disease activity in lupus patients.
💡 Smarter steroid use = better outcomes.
👉 Watch now on RheumNow:
https://t.co/vbjrXAlixz
#Lupus https://t.co/TN5EkZhbef
Links:
Dr. John Cush RheumNow ( View Tweet)
🔓 Lupus Unlocked: Antiphospholipid Syndrome
📅 Tuesday, May 20, 2025 | 🕕 Time: 6:00 PM CT | 7:00 PM ET | 4:00 PM PT
Live Webinar w/ Q&A
Register Today: https://t.co/71NJsmBNf3
Livestream: X, LinkedIn, YouTube, Facebook
This session is designed to provide practical insights https://t.co/jAtduyzl0l
Dr. John Cush RheumNow ( View Tweet)
FDA approved the chikungunya virus vaccine (Ixchiq) in 11/23, but recently announced caution and pause use while it investigates Postmarketing Safety Reports of 17 SAE (cardiac & neurologic) & 2 deaths. 6 SAE in the USA, elderly w/ chronic med conditions. ~80K doses of Ixchiq https://t.co/RED8Xab0Ir
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3-year, RCT of Mediteranean diet vs usual care in 924 older adults w/ metabolic syndrome & BMI > 27. Med. diet shows signif wt loss (3.4% vs 0.4%), w/ improved BMD (by DEXA) at year 3, especially in women. https://t.co/mllx6l1QnM https://t.co/I5e8PXX2oX
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Clinical Impacts of the Pre Lupus State on Pregnancy Outcomes
Dr. Catherine Sims talks with Dr. Jessica English at the RheumaPreg 2025 meeting in Vienna, Austria.
https://t.co/T8ZYQtDNmZ https://t.co/PmVRFVlABd
Dr. John Cush RheumNow ( View Tweet)
Smoking & Autoantibodies in Rheumatoid Arthritis
Investigators from the Netherlands have published their findings that smoking is a risk factor in rheumatoid arthritis (RA), led by the induction of local autoimmune responses at mucosal sites (in the lungs) and exemplified by https://t.co/SQa3PrRnOI
Dr. John Cush RheumNow ( View Tweet)
Deep remission in SLE – what is it, and can we achieve it?
Recent reports on lupus patients treated with CAR-T cells targeting CD19+ B lymphocytes have sparked excitement. This is due to the patients experiencing ongoing clinical remission without further treatment after two https://t.co/rdBkIhfWWd
Dr. John Cush RheumNow ( View Tweet)
Lupus QD Clinic - SLE Get Ready
Young SLE patient wants to get pregnant; but first she needs to get ready!
Features Dr. Jack Cush
https://t.co/988jrHmdUs https://t.co/qVrBU2lvI5
Dr. John Cush RheumNow ( View Tweet)
FDA approved the chikungunya virus vaccine (Ixchiq) in 11/23, but recently announced caution and pause use while it investigates Postmarketing Safety Reports of 17 SAE (cardiac & neurologic) & 2 deaths. 6 SAE in the USA, elderly w/ chronic med conditions. ~80K doses of Ixchiq https://t.co/XadqMEmSuD
Dr. John Cush RheumNow ( View Tweet)
