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#ACR21 Year In Review: Factors associated with #COVID deaths in pts with #RMD:
⛔️age, male, HTN/CVD, lung disease, steroid>10mg/d, ⬆️disease activity
⛔️RTX (OR: 4), SFZ (3.6), other IS (2.2), No DMARDs (2.1) vs MTX monotherapy as reference @RheumNow https://t.co/Zd6qXCtGLk https://t.co/YHBEelLqKB
Links:
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#Abstr0076 #ACR21 Can we predict #thrombosis in #lupus patients? Predictors of serology transition at 5yrs:
✅LAC+ to LAC-:Afro-American,HCQ and normal C3
⛔️LAC+ to 🩸Clot:Obesity, low C3 and not on HCQ
Data need in those with Triple Positivity @RheumNow https://t.co/byeL5NjVUS https://t.co/CchtZir2GN
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#Abstr0002 #ACR21 What drives salt in saliva in #sjogren? A study suggested Bcell cytokines mediated the epithelial Na+ Channel disruption. A case for targeting Bcell to improve oral health @RheumNow https://t.co/Bx3kBpOIFX https://t.co/YYnC6UoMJY
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Either we need to review the Yearly PAP cervical screening in SLE women or work hard to improve patient awareness. Suspect the latter as time between tests was over 4 years late 😱 and 2.7% developed cancer #ACR21 #Abstr0133 @RheumNow https://t.co/wm01MfoFjf https://t.co/blD8WafZsE
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#ACR21 #Abstr0454 Mortality rate in #lupus nephritis ⬇️by 26% from 1999-2019👏. BUT, racial and residence disparities were concerning; worse in Black, Hispanic, Asian, AI/AN vs White and in large central and medium metro. Residential matters! @RheumNow https://t.co/33vN39acuL https://t.co/XMwN2hXJn7
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#ACR21 #Abstr0768 We need to improve disparity among all levels of income. Support to the lowest income group seemed to improve but children with #lupus who were in the 2nd level income quartile had the longest length of stay in the hospital #RheumNow https://t.co/7HSveerUhs https://t.co/cSQBELopH5
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
A very strong and inspirational opening session quote "Create new better normal where you can create systems that are resilient to a crisis and the foundation trend towards paradigm shift after what the pandemic has brought to light the gaps" #ACR21 #RheumNow @DoctorYasmin https://t.co/Ikbt9LiPwu
swethaann23 swethaann23 ( View Tweet)
@DoctorYasmin: "Let's talk about the history ... let's build bridges." We individualize approach to treatments, we should also individualize our conversation about vaccine hesitancy to your patient's specific concerns. @rheumnow #ACR21 https://t.co/1Jxw8l2phB
Eric Dein ericdeinmd ( View Tweet)
Looking forward to “What the fact” – how to differentiate from misinformation versus actual information in social media @DoctorYasmin @DrDavidKarp #ACR21 @RheumNow https://t.co/Wqh29NWNmq
swethaann23 swethaann23 ( View Tweet)
A quick recap slide on VEXAS syndrome presentation. #ACR21 @RheumNow @petercgrayson https://t.co/4x8hBEFWg2
swethaann23 swethaann23 ( View Tweet)
Avacopan (C5a inhibitor) is a new promising therapy for ANCA vasculitis. US FDA approved in Oct 2021
#ACR21 @rheumnow https://t.co/tWvKzHOT5V
swethaann23 swethaann23 ( View Tweet)
Findings:
1. 21% of the patients in the Ankylosing Spondylitis Registry of Ireland (ASRI) were unemployed which is higher than their national average.
2. Stong predictors of unemployment were - Male sex and worse disease activity outcome measures(BASMI and ASQoL)
#ACR21 @RheumNow
swethaann23 swethaann23 ( View Tweet)
#ACR21 @RheumNow
Abst#0359 by Garrido-Cumbrera et al. has mapped out the journey from symptom onset to diagnosis of axSpA across 13 European countries.
swethaann23 swethaann23 ( View Tweet)
#ACR21 @RheumNow
Abst#0364 by Wetterslev et al. sought to identify axSpA characteristics of patients tapered off TNFI and showed clinical and radiographic improvement.
🔽52% were tapered off
⭐️The highest predictor of success is a low physician global VAS score
swethaann23 swethaann23 ( View Tweet)
Our recap of Day 2 of #ACR21 is now available on YouTube and the @RheumNow website, where you can find lots more videos, interviews and articles from the conference!
https://t.co/BxBXipxzif
@drdavidliew @doctorRBC @swethaann23 @MeralElRamahiMD
Mrinalini Dey DrMiniDey ( View Tweet)
⭐️AxSpA pts with decrease in oral microbial diversity
⭐️Immune response to oral/fecal microbes altered in AxSpA pts.
⭐️HLA-B27 associated ⬆️IgA coated microbes, may contribute to development of AxSpA
Abs#0052
https://t.co/NQgm0lpYJj
#ACR21
@RheumNow
Links:
Robert B Chao, MD doctorRBC ( View Tweet)
Dr Preger report 9 novel aminoacyl tRNA synthetases in IIM patients. May these allow us to spare more patients biopsy? Abstr#0001 #ACR21 @RheumNow https://t.co/ikNXCEOeuj
Richard Conway RichardPAConway ( View Tweet)
Meta-analysis from @rheum_covid with @HsiehEvelyn shows that people with rheumatic disease are at⬆️risk of SARS-CoV-2 infection and⬆️mortality from COVID-19. Abstr#0086 #ACR21 @RheumNow #ACRBest https://t.co/B7tWs02gfc
Richard Conway RichardPAConway ( View Tweet)
Dr Doliner @zach_wallace_md on ILD in AAV. ILD in 13% - of which 76% fibrotic. UIP most common. Most MPO+, but also rarely seen with PR3+. 47% ⬆️ risk of death. Abstr#0430 #ACR21 @RheumNow https://t.co/6MnxqW92bz
Richard Conway RichardPAConway ( View Tweet)
Completely new one for me, Dr Taniguchi presenting on using ear ultrasound to diagnose and monitor disease activity in relapsing polychondritis. Appears useful, I suspect in clinical practice more so for diagnosis. Abstr#0169 #ACR21 @RheumNow https://t.co/PLJtkYkP3A
Richard Conway RichardPAConway ( View Tweet)