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Fun things at #ACR21. Abs1186 #Kardashian index:
K-index = # of followers on Twitter/expected # of followers based on citations.
⭐️Only 1 program director (PD) had K-index>5, an "academic Kardashian"
⭐️Only 11 PDs on Twitter had >100 followers
https://t.co/uH408ri5nY @Rheumnow https://t.co/d8VeyzAIcU
Links:
Eric Dein ericdeinmd ( View Tweet)
Impressive case of vasculitis – should be part of @ACRheum image bank #ThievesMarket #ACR21 Abst#TM20 @rheumnow https://t.co/YiBikROuzb
TheDaoIndex KDAO2011 ( View Tweet)
They are the up and coming leaders in our field! I got to interview them about
👉🏼why #GeriRheum is important (our pts are aging)
👉🏼small changes to your practice for big outcomes
👉🏼Tips: pain control/funx #acr21 @UnaMakris @RheumNow https://t.co/f71L0P3foE via @YouTube
TheDaoIndex KDAO2011 ( View Tweet)
Pirfenidone in RA-ILD, TRAIL-1 study. Long-awaited. Early termination due to COVID led to under-powering. Slowed decline in FVC, especially in UIP pattern. Seemed to have less adverse events than we see with nintedanib. Abstr#L10 #ACR21 @RheumNow https://t.co/sYRDhG3u4y
Richard Conway RichardPAConway ( View Tweet)
Artificial neural network showed good generalizability and a high specificity with acceptable sensitivity in the detection of radiographic sacroiliitis. A tool for interpretation of sacroiliac radiographs as a part of the diagnostic approach @RheumNow #ACR21 Abst#1919 #ACRbest https://t.co/SdmomEWwya
Dr. Antoni Chan synovialjoints ( View Tweet)
New dimensions in cellular immunology. Great session, some which I understood. Kids with #JIA have more cytolytic pathway missense - some leads to macrophage activation syndrome #MAS Low NK cells in Juvenile Dermatomyositis. 9T112 #ACR21 @RheumNow https://t.co/5lUkqr65UM
Janet Pope Janetbirdope ( View Tweet)
Adipokines in RA
⚡️Highest Quartile Adiponectin associated w/ ⬆️ all-cause mortality HR 1.46 ⬆️ CV mortality HR 1.85
⚡️Highest Quartile Leptine ⬆️ 25% all-cause mortality
#ACR21 #Abst1645 @RheumNow
https://t.co/O1NAbfMvif https://t.co/VVdgZHP1j5
Links:
Aurelie Najm AurelieRheumo ( View Tweet)
No clear excess risk for offspring exposed in-utero to, VED or TNFi's. UST showed infection signal BUT w/ wide CIs. We need more research re: biologics and placental transmission potential/subsequent risks. Abs 1713 #ACR21 #RheumNow #ACRbest @RheumNow https://t.co/W3K5uDyHlC
Dr. Rachel Tate uptoTate ( View Tweet)
b/tsDMARDs + tumor response in rheum irAEs
Excellent point by @CCalabreseDO @LCalabreseDO:
- despite progression in 5/10, DMARD contribution uncertain (bad cancer)
- without DMARD, ICI would have had to stop
crucial question, prospective study needed
#ACR21 ABST1519 @RheumNow https://t.co/omJnTNVscH
David Liew drdavidliew ( View Tweet)
The wave of the future? Study details immune profile which discriminates PsA from PsO using phenotyping of serum immune cell subsets & machine learning. Abs 1774 #ACR21 #RheumNow #ACRbest @RheumNow https://t.co/huNTY3IdRf https://t.co/3aW64pb9UW
Dr. Rachel Tate uptoTate ( View Tweet)
Great case where the #COVIDvaccine was blamed, but he had a diet of doughnuts, steak&cheese sandwiches w/snack cakes, and popsicles. #ThievesMarket #ACR21 @rheumnow https://t.co/J78Nw5NhKs
TheDaoIndex KDAO2011 ( View Tweet)
The #ACR21 Playbook
This playbook is designed to help you navigate a truly big meeting (with >2000 presentations and over 15,000 attendees from over 100+ countries). What follows is based on experience and the acquired insights our peers.
https://t.co/GlDOnVfHsc https://t.co/RQlM2fjCzY
Links:
Dr. John Cush RheumNow ( View Tweet)
Autoantibodies are underrated in rheumatic irAEs (?B cells in general), but probably not your usual.
If Ab are of interest, suspect we're going to have to look at non-classical ones
Elegant from @NilashaGhosh @MPostow @got_rheum @lovetolearn27 #ACR21 ABST1520 ABST1521 @RheumNow https://t.co/tLSJOZw1YG
David Liew drdavidliew ( View Tweet)
Great conversation with @BayviewMedicine @jhrheumatology alum Dr. Jason Liebowitz and Professor Janet Zeide on "Gift of Gab"- communications skills for the rheumatologist at #ACR21! @Rheumnow https://t.co/O1u3X8urag
Eric Dein ericdeinmd ( View Tweet)
Abst1783 #ACR21 #ACRBest @RheumNow Canadian study reports promising trends on hospitalizations for serious infections in PsA: 2012 – 2017 statist signif ⬇️ in discharges for sepsis, skin & soft tissue infect & UTI (p < 0.001 for all). no statistical difference in the trend of PNA https://t.co/lqtCzUFPAW
Olga Petryna DrPetryna ( View Tweet)
We may be getting a new urate lowering therapy. Tigulixostat is a non-purine selective xanthine oxidase inhibitor. Nothing worrying on safety. But I think febuxostat is probably more effective than this? Abstr#L05 #ACR21 @RheumNow https://t.co/Lg0slMlah2
Richard Conway RichardPAConway ( View Tweet)
Upadacitinib showed similar efficacy in AS pts compared to PsA pts with axial involvement
⭐️PsA pt w/ axial involvement and AS pts with differences in baseline characteristics
#ACR21 @RheumNow
Abs#1802
https://t.co/QvyayelBYU https://t.co/50dNQm30vf
Links:
Robert B Chao, MD doctorRBC ( View Tweet)
How do RA pts go with ICI cancer therapy?
@VUMCRheum audit reflects overall prev experience:
- approx 50% flare (?some reflect DMARD W/H)
- flares overwhelmingly managable
- few (1/19 here) cease ICI due to RA flare
RA pts deserve best cancer Rx too!!
#ACR21 ABST1523 @RheumNow
David Liew drdavidliew ( View Tweet)
Advantages of treat to target (of serum urate) beyond less gout flares? Maybe equal to ⬇️MACE events - I hope in long term less MACE due to less ⬆️CRP w flares. Modelling observational study abst#L06 #ACR21 #ACRBest @RheumNow below is comparative safety T2T better than usual care https://t.co/95M6lNX416
Janet Pope Janetbirdope ( View Tweet)
Dr. Despotovic shares general principles about ICU admissions in patients w/ #rheumatic disease.
🔺#SLE, RA, systemic #vasculitis, SSc, IIMs
🔺serologic testing useful but interpret w/n clinical context
@RheumNow #ACR21 https://t.co/jb3Mt31dZz
sheila RHEUMarampa ( View Tweet)