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What is JAKne? (5.6.2022)
Dr. Jack Cush reviews the news, journal reports, FDA actions, new side effects and changing prevalence of Gout.
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Lack of Research Stymies Uptake of Medical Marijuana for Rheumatic Pain
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Creaky Joints
A new review article from CreakyJoints finds that there has been limited progress in understanding the potential of cannabis based therapies for the treatment of pain associated with rheumatic conditions in the past five years because of a lack of standardization of clinical research and barriers to conducting research due to existing federal and state regulations.
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Algorithmic approach to SLE and assessing/treating early pregnancy. #UTSWSLE2022 https://t.co/692el4R9sZ
Dr. John Cush RheumNow ( View Tweet)
Adverse pregnancy outcomes and Risks in #SLE. (Dr. Eliza Chakravarty - OMRF) #UTSWSLE2022 https://t.co/HqscJD2m96
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Long acting reversible contraceptives (LARC) are recommended in #SLE. #UTSWSLE2022 https://t.co/oFyNTHzVAj
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Nearly 40% of all #SLE pregnancies are unplanned - hence, contraception (unused in 73%) and education are paramount in management of women w/ SLE. (Dr. Lisa Sammaritano- HSS) #UTSWSLE2022 https://t.co/ooryrW9GGn
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An increasing incidence of RA is driven by increasing # of ACPA-negative RA (but not ACPA-positive RA), partly explained by an ageing population (thus making ACPA-negative RA more prevalent in coming years) https://t.co/9vC8aCphKc
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"I think we can get rid of maintenance prednisone in nonrenal lupus" (but not in renal lupus)
"...prednisone contributes to some organ damage (but not renal)"
Organ damage is multifactorial -traditional risk factors, disease activity & steroids
- Dr. Michelle Petri #UTSWSLE2022 https://t.co/N9NMPgtPEn
Dr. John Cush RheumNow ( View Tweet)
"How awful is our current prednisone practice"
- Dr. Michele Petri #UTSWSLE2022 https://t.co/WGNx5yxF8x
Dr. John Cush RheumNow ( View Tweet)
From the Hopkins Lupus cohort - Just one month of Prednisone 40 mg/d yields a FOUR fold increase in avascular necrosis risk #UTSWSLE2022 https://t.co/RGP06PUIKH
Dr. John Cush RheumNow ( View Tweet)
DOCTORS: are you ready to attend big medical meetings ? @LCalabreseDO
Dr. John Cush RheumNow ( View Tweet)
Large Korean population study compares pts w/ palmoplantar psoriasis vs psoriasis and PPP pts have more risk for ankylosing spondylitis (aOR 1.37) & Graves dz (aOR 1.4) but lower risk for PsA (aOR 0.54), SLE (0.67); Sjögren (0.70); vitiligo (0.53) https://t.co/0fv2vnFBPf https://t.co/PJMagIeZ2F
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UT Southwestern Symposia on "Future of SLE". Summary of Disparities in SLE Care/Outcomes (from Dr. Candace Feldman - Harvard). #UTSWSLE2022 https://t.co/KQb9JV7uJU
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Yet another examples of underrepresentation of minority groups in clinical trials! #UTSWSLE2022 https://t.co/TbhhdglJ6v
Dr. John Cush RheumNow ( View Tweet)
How do we solve/address the problem of Health Disparities in Lupus and Rheumatology? Dr. Ashira D Blazer, MD @ashira_md (HSS) approach:
Study
Listen
Educate
Partner
Diversity
#UTSWSLE2022 https://t.co/w3DX1w0chy
Dr. John Cush RheumNow ( View Tweet)
Danish case-control registry of 491,274 women shows Psoriasis assoc w/ increased risk of ectopic pregnancy (EP) (OR 1.34), highest in women w/ moderate-to-severe psoriasis (OR 2.77). EP risk was 2.5x higher for women w/ mod--severe PSO https://t.co/vUtNEMDOhr
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Trends in RA Disability, Despite Biologics
Disability claims in the U.S. related to RA were just as common in 2015 as in 1999, a gov't researcher found, against expectations that the advent of biologic therapy would have led to a steady decrease.
https://t.co/vyyjTbkLN2 https://t.co/D5Eo42P4cw
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Study of 17 homeless RA or PsA pts - less clinic access (80% vs 91%), more ED use (20 vs 5), less DMARDs (43% vs 100%), more steroids (29% vs 0%); 83% unable to work due to health. Greatest need - dental , PT, knee surgery, employment & housing https://t.co/VHnTR0MTkr https://t.co/JDZTELz2qB
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Gout affects >10 million (4%) in USA, but now w/ more ethnicity, with highest risk in Native Hawaiians (HR 2.21), followed by Black (1.34) and Japanese (1.14); but lower in Latinos (HR 0.78) compared to whites. https://t.co/lQiSx0ExAM https://t.co/bVx41mbquW
Dr. John Cush RheumNow ( View Tweet)
There is 1.4 million transgender persons in the US. ACP has published a guideline "Care of the Transgender Patient" addressing health disparities, certain cancers, substance abuse, mental health conditions, infections, and chronic diseases. https://t.co/AoBeOzv9YH https://t.co/jKabVELPxH
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