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#ACR21 Rheum Secrets and Pearls
High CRP - not a typical marker of SLE flare. Look for infection!
@Rheumnow https://t.co/g1Z6OHvANv
Eric Dein ericdeinmd ( View Tweet)
Do you use RAPID3 in PsA?
Abst#0633 at #ACR21 shows a strong agreement between RAPID3 remission score w/ DAPSA + cDAPSA, esp when redefining RAPID3 categories.
Is this practice △ing? With more studies to validate, yes, since RAPID3 is simpler!
@RheumNow https://t.co/2q0FLeBSkC https://t.co/M3WDTGzEOT
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Always one of my favourite sessions at #ACR21- #Rheumatology #SecretsAndPearls
Dr Kolfenbach reminds us of the importance of discussing #lifestyle, #smoking and #diet with our patients in clinic.
@RheumNow #InflammatoryArthritis #RheumatoidArthritis #PsA https://t.co/2gadRBLCTb
Mrinalini Dey DrMiniDey ( View Tweet)
VITAL RCT of Omega-3 and Vit D in preventing autoimmune diseases in 25,871 individuals. They both work! Reducing incident autoimmune disease by 25-30%. This is game-changing! Abstr#0957 #ACR21 @RheumNow #ACRBest https://t.co/BaeZDTTnQf
Richard Conway RichardPAConway ( View Tweet)
Elevated CRP? Dr. Kolfenbach reminds us that it is not typical of #SLE flares, rule out INFECTION!
@RheumNow #ACR21 #RheumTwitter #MedTwitter https://t.co/FnkPdZ8gSl
sheila RHEUMarampa ( View Tweet)
"We need to do more than improving quality of care to close the gap in racial disparities." - Dr. J Chang
Trends of adverse renal outcomes⬇️w/time in children hosp w/SLE. Improvements seen across racial/ethnic group, but black-white disparity persists abst#0956 #ACR21 @rheumnow https://t.co/HcOwQiKCb2
TheDaoIndex KDAO2011 ( View Tweet)
#ACR21 Rheum Secrets and Pearls
Is it Allopurinol or adherence concern?
Oxypurinol can be helpful in measuring adherence!
Kolfenbach: "I despise the term non-compliant patient." Address the many reasons why adherence may be low! Health literacy is key.
@Rheumnow https://t.co/CPJ8kvqcCm
Eric Dein ericdeinmd ( View Tweet)
Although baseline dz was similar in axSpA males/females, study found male pts had more improvements in ASDAS-CRP, CRP, and PGA than females in 6 years of follow-up. Abs 0620 #ACR21 #RheumNow @RheumNow https://t.co/Qr657YeniA https://t.co/35t4oIUSmS
Dr. Rachel Tate uptoTate ( View Tweet)
An ongoing axSpA cohort in Netherlands study assessed the rate of progression of nr-axSpA to AS patients over a 6 y period
Every 2 y approximately 10% of patients progressed from nr-axSpA to AS
Abst # 0907 #ACR21 @RheumNow https://t.co/gGhhssLS5N
swethaann23 swethaann23 ( View Tweet)
#ACR21 Abst#0836. TCZ switch from IV▶️SC in RA
⭐️11/37 ineffective on SC (30%)
⭐️TCZ IV >8mg/kg, no MTX, h/o ABA failure ass w/ risk of flare on SQ switch
🔥Very relevant w shortages, want more data re: confounders (adherence, disease control)
https://t.co/E9pD4SrXqz @Rheumnow
Links:
Eric Dein ericdeinmd ( View Tweet)
Getting closer to personalised medicine in AS, ECM-mediated biomarkers may help predict response to Adalimumab in AS. The biomarkers C1M, C6M and
PRO-C4 were lower in responders to adalimumab treatment after 24 weeks @RheumNow #ACR21 Abst#0915 https://t.co/K2YxPvUAwu https://t.co/w9kcBSFeG9
Dr. Antoni Chan synovialjoints ( View Tweet)
Interesting study. 79 nr-axSpA pts observed for 6 years. Every 2 yrs approximately 10% of pts progressed from nr-axSpA to AS! Next step: evaluate dz characteristics and determine potential at risk pts. Abs 0907 #ACR21 #RheumNow @RheumNow https://t.co/aRjXWjkVKg https://t.co/BiHFgDR8Kv
Dr. Rachel Tate uptoTate ( View Tweet)
Abst0898 #ACR21 @RheumNow MRI findings of Vertebral Corner Inflammation & Vertebral Corner Fat Deposition associated w/syndesmophyte formation 2 y later, ORs 1.87-2.58 for various VCI/VCFD patterns. Protection against syndesmophyte seen if both VCI and VCFD were absent (OR 0.35) https://t.co/t01nxdEwON
Olga Petryna DrPetryna ( View Tweet)
Younger patients and African Americans have a high no show rate. Need to focus on high-risk individuals and improve access to new patient appointments. @rheumnow #ACR21 abst#0610 https://t.co/3XZmXWfili
Bella Mehta bella_mehta ( View Tweet)
Monozygotic twin study in PsO patients showed a gut and skin microbiome difference compared to their "normal" twin
⭐️Ruminococcus decreased/absent in gut flora of PsO
⭐️microbiome differences even in healthy PsO skin
Abs#944
#ACR21
@RheumNow
#ACRBest
https://t.co/VlfVh5Kt3Y https://t.co/W0eSqi77lx
Robert B Chao, MD doctorRBC ( View Tweet)
This slide 👇 from Dr. Mary Crow's lecture shows how 2 categories of autoantibodies with their distinct functions can allow for different therapeutic targets in #lupus
@RheumNow #ACR21 #rheumatology https://t.co/wkthvj21cE
sheila RHEUMarampa ( View Tweet)
There is increase in ASDAS, BASDAI, CRP and faecal calprotectin levels although not reaching a clinical flare in AS patients who had CZP stopped compared to those who continue CZP full or reduced dose @RheumNow #ACR21 Abst#0916 https://t.co/Wlwirs1QXF https://t.co/jE4smHMXBI
Dr. Antoni Chan synovialjoints ( View Tweet)
#ACR21 Hench Lecture. Wonderful talks by Peggy Crow on #lupus pathogenesis. Tour de force since LE cells discovery. Potential sources of self-nucleic acids:
💠Endogeneous retroelements LINE-1
💠Mitochondria
💠Cell-derived nuclear debris (NETs, apoptotic)
@RheumNow https://t.co/TSdyqblYaA
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Do you have trouble with no shows? Study out of Allegheny Health showed younger and black patients were among characteristics of pts at risk for new pt exam no shows. How can we do better for these pts? Thoughts? Abs 0610 #ACR21 #RheumNow @RheumNow https://t.co/MUcQarwvm6 https://t.co/Mue6By5mOV
Dr. Rachel Tate uptoTate ( View Tweet)