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Lots of excellent abstracts at #ACR21 on assessment & impact of #comorbidities & #multimorbidity in RA, some discussed in this article @RheumNow:
https://t.co/WXgv1GmHD6
Featured abstracts:
#0798 https://t.co/02BRqYp9Yk
#1450 https://t.co/iG2s2Cy8Q0
#1924 https://t.co/qHws6ALENH
Links:
- Towards better assessment and management of multimorbidity | RheumNow
- The Impact of Comorbidities on the Simple Disease Activity Index (SDAI) and Its…
- Unsupervised Machine Learning Methods to Cluster Comorbidities in a Population-…
- Patient Clustering Based on Multimorbidity Patterns Predicts Healthcare Utiliza…
Mrinalini Dey DrMiniDey ( View Tweet)
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Cool talk by P Grayson - how to design ANCA vasculitis RCTs with biomarkers, umbrella/basket RCT designs to treat pts MORE likely to respond. Also for an individual, following ANCA is not that helpful for altering Rx Take a look at this session GS401 #ACR21 #ACRBest @RheumNow https://t.co/nrapO9i4gw
Janet Pope Janetbirdope ( View Tweet)
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Abst 0478
Binvignat et al performed hierarchical clustering analysis based on cardinal symptoms in hand OA
- Identified 5 Phenotypes
- Symptoms correlated with metabolic syndrome, joint destruction & physical and psychological burden
#ACR21 @RheumNow https://t.co/O9hweqNIS8
Akhil Sood MD AkhilSoodMD ( View Tweet)
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Bimekizumab (IL-17A and IL-17Fi) 3 year safety and efficacy in PsA Phase IIb trial
⭐️no new safety signals
⭐️candida infections were all mild/moderate
⭐️efficacy consistent and maintained
Abs#491
#ACR21
@RheumNow
https://t.co/BK6xPMqAEM https://t.co/meoPd7k0Xp
Robert B Chao, MD doctorRBC ( View Tweet)
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Dr. Atul Deodhar with an excellent presentation on treatment in axSpA and axPsA. Note ustekinumab and risankizumab did not show improvement in axSpA. However, these studies did not include axPsA.
@ACR21 6S403 @RheumNow https://t.co/F73lvpF2at
Pedro Castillo _Castillo_Pedro ( View Tweet)
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More from Dr. Atul Deodhar on treatment of axSpA and axPsA. Guselkumab studies DISCOVER 1 & 2 looked at PsA with sacroiliitis and demonstrated improved measures of axial activity, but we need more studies and to include MR imaging.
#ACR21 6S403 session @RheumNow https://t.co/8jM5Fj8MuD
Pedro Castillo _Castillo_Pedro ( View Tweet)
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Abst 0370 #ACR21 @rheum survey of PCPs reveals lack of awareness about inflammatory back pain: 58%never/rarely assess for IBP; 40% not comfortable with making the dx of IBP. 83%never/rarely ordered HLAB27, 65% never/ rarely ordered CRP, 72% rarely/never ordered X-ray SI joint
Olga Petryna DrPetryna ( View Tweet)
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New therapies this year in rheumatology #ACR21 year in review Avacopan in AAV and Voclosporin in Lupus nephritis @RheumNow @karen_kc123 https://t.co/8Z28STMJ6X
Bella Mehta bella_mehta ( View Tweet)
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Using machine learning to predict knee cartilage worsening over 2 years sing gait and physical activity using the MOST study #abst0210 #ACR21 @RheumNow https://t.co/0MAjLhpL7t
Bella Mehta bella_mehta ( View Tweet)
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Overlap between RA and SLE: is the famous rhupus more frequent than it seems? In the Boston OM1 SLE Registry w/ 44,186 SLE: 4.7% also reported as having RA. This is higher than the usual reported prevalence. #ACR21 #Abst0354 @RheumNow https://t.co/FYfvSdCkkF https://t.co/ISuae2hCI3
Aurelie Najm AurelieRheumo ( View Tweet)
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Abst 0281 England & colleagues used unsupervised ML to determine whether peripheral biomarkers can accurately identify RA-ILD in large RA cohort
- Identified 8 unique groups based on biomarkers
- RF, anti-CCP, and -MAA biomarkers most closely associated w/ ILD https://t.co/831tP4JSh0
Akhil Sood MD AkhilSoodMD ( View Tweet)
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Rheumatologists and Health Professionals: Join us tonight for RheumNow's #ACR21 Daily Recap at 7pm Eastern time . Register via the Zoom link below.
https://t.co/IQSL0mpEjR
Or visit our YouTube channel-RheumNow.
https://t.co/Nm74eS5T5H https://t.co/syaHSDJWOv
Dr. John Cush RheumNow ( View Tweet)
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PsA patients should be screened for spinal involvement, which may not be picked up on initially if we aren't looking for it. Presented by Dr. @annamolto
#ACR21 6S403 @RheumNow https://t.co/frB2zbHtXG
Pedro Castillo _Castillo_Pedro ( View Tweet)
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Early CV changes in #Rheumatoidarthritis abst#0271 showed more subclinical atherosclerosis vs controls in ERA, Abs ⬆️MACE &CV death in RA pts, abst#0269 ex RF, ACPA, MAA. Lipids ⬆️differently in RA given #tocilizumab vs TNFi BUT unrelated to CV events abst#0269 #ACR21 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
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#ACR21 The Great Debate: Belimumab vs Voclosporin as Add-On Therapy in #LupusNephritis | Dr. Petri & Dr. Rovin
Audience Vote 🗳: What would you add to mycophenolate first?
Belimumab 71%, Voclosporin 29%
#ACRAmbassador @ACRheum
Summary of Pros & Cons of Each⬇️ https://t.co/OtLxs8IYr9
Mithu Maheswaranathan, MD MithuRheum ( View Tweet)
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Young et al. Impact of COVID-19 on rheumatology training
302 rheumatology trainees from 33 countries surveyed
➡️52% feel burned out🔼from prior
➡️66% felt supported by their program
➡️72% felt positive about being in Rheumatology
Abst#0485 #ACR21 @RheumNow @kristenyoung
swethaann23 swethaann23 ( View Tweet)
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Excellent talk by Dr. Anna Molto. Characteristics of spondyloarthritis, noting some patients with PsA have radiographic and non-radiographic axial SpA.
#ACR21 6S403 @RheumNow https://t.co/ycftOMrWO9
Pedro Castillo _Castillo_Pedro ( View Tweet)
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Do you use ANCA to change Rx in prevalent GPA pts? GS401 #ACR21 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
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OMG, the fear of missing something due to the discordant daylight savings shift is real! https://t.co/1mi2QnrHDl
Richard Conway RichardPAConway ( View Tweet)
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@kristenyoung @rheum_covid project on impact of COVID-19 on our trainees. Love the graphics by @EBRheum . Negatives are physical health, stress levels, and burnout all ⬆️ . Positives? Trainees did feel supported by programmes. Abstr#0485 #ACR21 @RheumNow https://t.co/kXQ1AUNrgb
Richard Conway RichardPAConway ( View Tweet)