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What Factors Predict RA in First-Degree Relatives?

d MedPage Today

Among a cohort of first-degree relatives of patients with rheumatoid arthritis (RA), certain patient characteristics, as well as symptoms, helped predict a possible increased risk for developing the disease, U.K. researchers reported.

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Booster Shots for Rheumatology Patients on Immunosuppressive Medications

d ACR Press Release

ATLANTA – The CDC's Advisory Committee on Immunization Practices today recommended that rheumatology patients being actively treated with high-dose corticosteroids, alkylating agents, antimetabolites, TNF blockers, and other biologic agents that are immunosuppressive or immunomodulatory receive a third dose of the Pfizer-BioNTech or Moderna mRNA COVID-19 vaccines.

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RheumNow Podcast – Booster Shots for COVID (8.13.2021)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.

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16 Pts on mech ventilation for SARS-CoV-2- induced ARDS with hyperinflammation were treated with ruxolitinib plus standard care - 13/16 survived 28 days. Better outcomes seen w/ RUX and Lymph-neutrophil ration > 0.07. https://t.co/4O2Y5swE0x

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Dr. John Cush RheumNow ( View Tweet)

In the week ending 8/12: 👧🏽121,427 pediatric #COVID19 cases (14.4% of all cases, 49 states) 🏥452 pediatric hospitalizations (24 states reporting) 💀7 pediatric deaths (43 states reporting) One death is too many.

Shematologist, MD acweyand ( View Tweet)

Here is a fairly obvious piece of advice: If a patient presents with a diagnosis (self-made) rather than a symptom, work hard to clarify the symptom itself. You usually make the same diagnosis but not always...

Adam Cifu adamcifu ( View Tweet)

Scottish study of 78 000 veterans shows no association between military service and future OA knee/hip. 78K Vets compared to 253K non-Vets shows Vets with a lower risk of THR (HR 0.87), but not TKR (HR 1.02). https://t.co/JU7Q80qji1

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Dr. John Cush RheumNow ( View Tweet)

Metanalysis of Colchicine in oronary artery disease (CAD) (13RCTs, n=13125), colchicine signif. reduces the risk of MI (OR 0.64) & CVA/TIA (OR 0.50), but has a higher rate of GI upset with no influence on all‐cause mortality (OR 0.96) https://t.co/CRDUFsc6lG

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Dr. John Cush RheumNow ( View Tweet)

Osteoarthritis vs. Rheumatoid Arthritis https://t.co/qvVEcKqNAM https://t.co/WDyIZxoL7v

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Dr. John Cush RheumNow ( View Tweet)
Watch Now: The Sentinel Joint: Dr. Kathryn Dao ( @KDAO2011 ) reviews abstract POS0385 presented at the virtual EULAR 2021 meeting. https://t.co/H3DcSHQWHr https://t.co/f7LDNz6oyL

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Dr. John Cush RheumNow ( View Tweet)
Popular on RheumNow https://t.co/BZsl8a6ArW The U.S. Food and Drug Administration (FDA) has approved Octagam 10% [Immune Globulin Intravenous (Human)], as the first and only intravenous immunoglobulin (IVIg) formulation to be approved for adult dermatomyositis (DM). https://t.co/RNFsJadUZx

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Dr. John Cush RheumNow ( View Tweet)
Popular post-- AstraZeneca announced that anifrolumab (Saphnelo or anifrolumab-fnia) was approved by the the FDA for that treatment of adult patients with moderate to severe systemic lupus erythematosus (SLE) who are receiving standard therapy. https://t.co/22HVA32IAh https://t.co/CGkBW80un4

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Dr. John Cush RheumNow ( View Tweet)
FDA has approved Xywav - gamma-hydroxybutyrate (GHB) for “idiopathic hypersomnia,” (people sleep 9+hrs/, yet never feel rested). GHB prev approved for narcolepsy https://t.co/38MBpmOAAA https://t.co/5pLLghCYtp

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Dr. John Cush RheumNow ( View Tweet)

A Top Tweet this Week: A large cohort study of rheumatoid arthritis (RA) patients shows that regular tea consumption was associated with a lower risk of RA. https://t.co/ODTs7PdGTN https://t.co/69mi8IlBdj

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Dr. John Cush RheumNow ( View Tweet)
In case you missed it… TB rarely causes arthritis; accounts for 1-5% of all TB (10-30% of pulmonary TB) cases. May present as mono/oligoarthritis, tenosynovitis, dactylitis, Spondylitis (Potts disease), reactive arthritis (Poncets dz) or polyarthritis. https://t.co/RpMrRLQbEa

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Dr. John Cush RheumNow ( View Tweet)

Dont make a point, make a difference - Seth Godin https://t.co/kJE3EGCY83

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Dr. John Cush RheumNow ( View Tweet)

ICYMI: Can you manage FM without opioids? Study of 698 Fibromyalgia pts from a tertiary center finds 27.1% taking opioids. Opioid associated with longer Sx duration (>3 yrs), increased age, worse functional impairment & pain catastrophizing https://t.co/N1G4ZtkUE5

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Dr. John Cush RheumNow ( View Tweet)

FDA has expanded the use of SHINGRIX vaccine to include adults 18 years and older who are compromised by immunodeficiency or immunosuppression caused by disease or therapy. https://t.co/Wf2mzvOQcU

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Dr. John Cush RheumNow ( View Tweet)

https://t.co/VBxg9fQmt0 Sporadic reports of anakinra use in COVID-19 infection has hinted is potential; now a metanalysis shows that the use of anakinra may reduce the mortality risk in patients admitted to hospital with moderate to severe COVID-19 pneumonia... https://t.co/XIB7OVNCvT

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Dr. John Cush RheumNow ( View Tweet)
Efficacy and safety of tildrakizumab in patients with active psoriatic arthritis: results of a randomised, double-blind, placebo-controlled, multiple-dose, 52-week phase IIb study https://t.co/XVXgEoufCw Nice data another p19 IL23 inhb - safety continues to impress

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Peter Nash drpnash ( View Tweet)

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