Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow.com. New regulatory decisions about JAK inhibitors and why do women with rheumatic diseases have unfair outcomes?
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Article
Article
Undiagnosed RA During the Pandemic
EurekAlert!
The number of new diagnoses of rheumatoid arthritis fell by 20% in the first year of the COVID-19 pandemic, new research suggests.
Article
Treat-to-target management of SLE has been shown to protect against organ damage and to improve quality of life. Now a prospective study shows that T2T with a goal of lupus low disease activity state and remission has been shown to improve mortality risk.
Article
The CDC has updated its Guideline for Prescribing Opioids for Chronic Pain and includes recommendations for managing acute (duration of <1 month), subacute (duration of 1–3 months), and chronic (duration of >3 months) pain.
2022 New Drug Approvals
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https://t.co/nz91Ckw0AZ https://t.co/QieTvcqjcy
One week away! #ACR22 https://t.co/bvFCfFpQom
“I am looking forward to the ACR to hear about the ground-breaking results from basic science to the new treatments. I am delighted to be part of the RheumNow faculty covering the many topics from #ACR22. “
Follow Dr. Chan at @synovialjoints for real-time coverage of #ACR22. https://t.co/i6OZRHlBaE
New regulatory decisions about JAK inhibitors and why do women with rheumatic diseases have unfair outcomes?
This and more on the latest RheumNow podcast.
https://t.co/4YBqHjI3VL https://t.co/g2pE72pyEk
“At the ACR I am looking forward to meeting colleagues in person, having some great food in Philadelphia and to learning alot as a RheumNow reporter!”
Dr. Janet Pope is back for #ACR22 as a RheumNow reporter, sharing real-time coverage on many topics. Follow her @Janetbirdope https://t.co/ROD7oan4KZ
SLE T2T - Lupus Low Disease Activity State Predicts Outcomes
A prospective study shows that T2T with a goal of LLDAS and remission has been shown to improve mortality risk.
https://t.co/WRaqjdVi9G https://t.co/3guKt0Qby9
2022 CDC Clinical Practice Guideline on Opioid Prescribing
The CDC has updated its Guideline for Prescribing Opioids for Chronic Pain and includes recommendations for managing acute, subacute, and chronic pain.
https://t.co/aFE4fUpIWn https://t.co/kG8QlVy2bG
Population study shows among vaccinated gout pts, COVID breakthrough infection occurred in @ 4.68/1K Pt-mos vs 3.76/1K Pt-mos in non-Gout persons. Gout w/ Covid had More Hosp (aHR=1.30) & death (aHR=1.36), moreso in Women w/ gout (aHR 1.55 & 2.46) https://t.co/ViwiPzqTbZ https://t.co/BrXd6pbgRI
Multinatinal cross-sectional survey of 2270 PsA pts shows despite comparable Dz duration, presentation, biologic use (54%), Women had worse QOL, more disability and work activity impairment (but less comorbidities) https://t.co/1KbDuxaMFf https://t.co/SsbSHQNsPV
BIOBADASER registry study of 969 axSpA pts (315 females, 654 males; 2000-2019) who initiated a TNFi shows nonresponse (BASDAI50) was more likely in women (p=0.018), older age at the start of TNFi therapy. https://t.co/Zp7PWhEMav https://t.co/1XY0dC0QCW
Single center study from UAB shows 72 gout pts treated & D/C from ED were Rx w/ steroids (64%), opioids (63%), NSAIDs (43%), colchicine (32%). But only 26/72 (36%) had subsequent outpatient clinic visit for gout. https://t.co/I8jjqIqJXd https://t.co/05YSibd6iz
JAK inhibitor labeling in Canada updated to include risks of MACE, fatal VTE and cancer for tofacitinib (Xeljanz) (also applied to Cibinqo, Inrebic, Jakavi, Olumiant, Rinvoq Xeljanz) https://t.co/FEbHE4wN3I https://t.co/EN80i9cY5h
Dr. Chao will be covering PsA and AS for the RheumNow team at #ACR22.
“I’m looking forward to the exciting hybrid format of both in person and virtual meeting this year!”
Follow @doctorRBC for real-time #ACR22 coverage. https://t.co/3sbBhVPPZ2
Introducing Dr. Akhil Sood, who will be covering #ACR22 on behalf of RheumNow.
He is excited to learn more about the cutting-edge research in the field of Rheumatology & Immunology.
Follow him @AkhilSoodMD for real-time coverage! https://t.co/hXw2CMrwKF
🆕Recommendation provided by Pharmacovigilance Risk Assessment Committee (#PRAC) about Janus kinase inhibitors #JAKi
⏩EMA recommends measures to minimise risk of serious side effects with #JAKi for chronic inflammatory disorders.
https://t.co/YqaX7UxtUA https://t.co/dCJbqanAxF
Catherine Sims, MD
Tweet
Think about checking Ig levels prior to Rituximab administration. Low IgM was most common after RTX in RA. The following are risk factors for hypogammaglobulinemia:
🧪 Older age
🧪 Use of steroids
🧪 Repeated doses of RTX
🧪 Low Ig at baseline https://t.co/oOjqnmFdYt


