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New GRAPPA 2021 PsO and PsA Treatment Recommendations by Dr. Rachel Tate ( @uptoTate ) The evidence-based recommendations from the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis were presented at #EULAR2021. Read more. https://t.co/AnHQGA8aKs https://t.co/yJbymc9csR

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Dr. John Cush RheumNow ( View Tweet)
Caveats: -secondary analysis (consider exploratory) -unclear clinical significance (modest ΔeGFR) -baseline CrCl 40+ (do NOT use in advanced CKD) -systemic rheumatic diseases excluded (unethical to randomize to PBO for 2 years) -generalizability (all had CVD, M>F, mean age 66)

Jeffrey Sparks MD MMSc jeffsparks ( View Tweet)

Results: MTX vs. PBO ✅Difference in least-squares mean ΔeGFR 0.93 mL/min/1.73m2 (p<0.001) ✅HR for kidney AE on safety labs: 0.73 (0.59-0.91) ✔️HR for kidney AE clinical events: 0.87 (0.56-1.36) ✔️4 vs. 8 severe kidney AEs (HR 0.50, 0.15-1.64)

Jeffrey Sparks MD MMSc jeffsparks ( View Tweet)

Unmet need to sort Undifferentiated connective tissue disease (UCTD; ANA+ve + =>1 criteria) as it impacts #psychosocial. Dr Siegel reported UCTD impaired #HRQoL and ⬆️anxiety, depression and fatigue. More works needed and to compare with #SLE and HC #EULAR2021 #POS0715 @RheumNow https://t.co/2elkeFmWwC
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
We need to revisit #SLEDAI #lupus arthritis. Drs Mahmoud & Vital reported only 48% without swelling had MSK-US synovitis; 90% with swelling. They proposed new TERM: Inflammatory joint pain with =>2 SJC. Need to get this right as it impacts SRI-4 #EULAR2021 #POS0746 @RheumNow https://t.co/JPqOMLQ2ES
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Very true. He pushes you to excellence. https://t.co/NTzrmHeGKD

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k dao KDAO2011 ( View Tweet)

SLE Molecular Phenotype for Personalized Medicine: Drs. Yusof and Garantziotis #EULAR2021 https://t.co/HJzyXBJ0fZ https://t.co/06jvGcczmi

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Dr. John Cush RheumNow ( View Tweet)
Would it help to record #SLE BILAG-2004 index in your busy clinic if this was made easy? Dr Carter reformatted EASY-BILAG with colour-coding and in-built glossary. Most assessment can be done in 1 page!This tool boosts accuracy, speed & usability #EULAR2021 #POS0748 @RheumNow https://t.co/v27rrK0ob3
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
HUR-BIO real life data, PsA pts started bDMARDs w/in 18 mo of dx vs almost 3x later in RA pts (tended to remain on csDMARDs.) This distinction may be explained by synthetic DMARDs on activity differences between the RA & PsA. Abstract #POS0633 #EULAR2021 https://t.co/VkkF28jm2f https://t.co/IkfGdZYNY3

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Dr. Rachel Tate uptoTate ( View Tweet)
@alberta_hoi @earlyarthritis @RheumNow Indeed. The #EULAR2021 session on this is one I have to go back and watch! https://t.co/0kLLQVbyWl
David Liew drdavidliew ( View Tweet)
Reassuring safety data from @rheum_covid COVAX registry on #COVID #vaccination in patients with #RMDs 👉🏼Vaccine welltolerated by most patients 👉🏼Most adverse events similar to gen population 👉🏼RMD flares were rare after vaccine 👉🏼#GetVaccinated! LB0002 @pedrommcmachado #EULAR2021 https://t.co/bheIcVZ9xa
Mrinalini Dey DrMiniDey ( View Tweet)
🤜MTX safe from kidney perspective if baseline CrCl 40+ 🤜Potential for immunomodulation to prevent/slow progression to CKD? Deserves dedicated studies @Nephro_Sparks

Jeffrey Sparks MD MMSc jeffsparks ( View Tweet)

Poster #POS0633 detailed HUR-BIO PsA pts started bDMARDs w/in 18 months of dx vs, on ave, 3x longer to start bDMARDs in RA pts in real life data. What do you drugs do you start in your PsA pts after dx? Feel free to detail me below! #EULAR2021 @RheumNow

Dr. Rachel Tate uptoTate ( View Tweet)

“Let thy food by thy medicine and thy medicine be thy food” Western diet - greatest enemy of chronic inflammatory conditions? ⬆️salt ⬆️refined carbs ⬆️omega 6 fatty acids ⬇️fiber, long chain omega 3 FA Abs#OP6882 #EULAR2021 @RheumNow

Robert B Chao, MD doctorRBC ( View Tweet)

Dr Schapp on nasal Staph Aureus eradication in ANCA vasculitis. Neither the presence or eradication of Staph Aureus appeared to influence the vasculitis @RheumNow #EULAR2021 Abstr#POS0249 https://t.co/bxtaznejNk
Richard Conway RichardPAConway ( View Tweet)
Practical tip from #EULAR2021 Pres6882: The difference a double bond makes: ⭐️Omega-3: Anti-inflammatory! ⭐️Omega-6: Pro-Inflammatory The ratio of ⬆️ omega-3 : ⬇️ omega-6 is key to anti-inflammatory diet @Rheumnow https://t.co/RtGWsDIouC
Eric Dein ejdein1 ( View Tweet)
A giant in our field. He has been my teacher for most of my career (since fellowship). He taught me how to care for patients, conduct research, & teach. My favorite quote is "If you're doing nothing, you're not doing anybody any good!" What is something he taught you? @rheumnow https://t.co/Fyw1u8wln8

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k dao KDAO2011 ( View Tweet)

Would you use #Telemedicine (TM) to follow-up #SLE patients post #COVID? Dr So showed in an RCT (N=122),patient satisfaction and time-to-review were better in TM vs Face-to-Face. Although none had COVID, >pts in TM were hospitalised and trend to⬆️FU #EULAR2021 #POS1164 @RheumNow https://t.co/p7aWv4AVm7
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
@almirall_m I don't monitor routinely. High rate of seroconversion post-TNFi but only small cases of TNFi-induced SLE (mild mostly). To screen with ANA if develop SLE features

Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)

Apremilast in Behcet’s - RELIEF European subgroup analysis ⬇️oral ulcer count, ulcer pain, disease activity ⬆️QoL ⭐️results consistent with general population Abs#POS0254 #EULAR2021 @RheumNow https://t.co/NVGt4TjkYY
Robert B Chao, MD doctorRBC ( View Tweet)
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