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Inflammatory Conditions Up the Risk of Premature Myocardial Infarction

d Jack Cush, MD

The European Journal of Preventive Cardiology reports that younger patients with their first myocardial infarction before age 50 yrs have a higher risk of having a systemic inflammatory disease (SIDs) and higher rates all-cause mortality.

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HLA B27 Iritis - RNL 2021 Highlights

d Rachel Tate, DO

The Spondyloarthritis Advances pod presented during the RheumNow Live 2021 conference featured three speakers, including an excellent lecture by Dr. Robert Wang, ophthalmology, on HLA B27 iritis and practical tips for rheumatologists. 

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Aortic Calcification and Lumbar Fracture Risk in Older Men

d Jack Cush, MD

Fractures of the spine and abdominal aortic calcification (AAC) can both be visualized with spinal imaging; a new report shows that finding both radiographic vertebral fracture and AAC on the same lateral spine images may predict the risk of future incident major osteoporotic fracture i

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Hypertension Unaffected by Urate Lowering Therapy

d Jack Cush, MD

Does uric acid contribute to the risk of hypertension (HTN)?  A recent cohort trial shows that allopurinol in young adults does not sufficiently lower blood pressure (BP).

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News Feature: Hypertension Unaffected by Urate Lowering Therapy Does uric acid contribute to the risk of hypertension (HTN)? A recent cohort trial shows that allopurinol in young adults does not sufficiently lower blood pressure (BP). https://t.co/PAMkgCc2DS #RheumNow https://t.co/ar7OiWKVQj

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Dr. John Cush RheumNow ( View Tweet)
263 RA patients with ILD were treated w/ Abatacept (ABA mono, ABA+MTX or ABA+nonMTX) - all improved their DAS28, stablized their FVC, DLCO, CHest CT; Only difference was that steroid sparing best when ABA used in combo. https://t.co/11vJCWOdSG https://t.co/yMF6imuFMV

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Dr. John Cush RheumNow ( View Tweet)
Abstract presented 10/20 at American Society Nephrology mtg show IV Pegloticase use in 136 ESRD dialysis pts (Rx by Rheums 68%). Pts were 73% males, avg age 57 years, More on hemodialysis [79%] than peritoneal dialysis [17%]. Pts RCV ~13 infusions. https://t.co/SFO8duqiy8

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Dr. John Cush RheumNow ( View Tweet)

Great coverage of #RNL2021 from Dr. Robert Chao @doctorRBC Fascinating talk by Dr. Robert Wang on uveitis. Pearls: -Anterior uveitis with hypopyon, will be B27+ -Hypopyon can be 2/2 Behcets and endopthalmitis -work up for Uveitis: B27, ACE/CXR, syphilis test #RNL2021 https://t.co/9DdNaAt7lx
Dr. John Cush RheumNow ( View Tweet)
News Feature: Psoriatic Disease Management - #RNL2021 Highlights This year’s coverage of psoriatic arthritis included an overview of the latest therapeutic options, a discussion on psoriasis specifically, and the epidemiology of psoriatic arthritis. https://t.co/wJ0pFgANhy https://t.co/SJezq1O7T4

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Dr. John Cush RheumNow ( View Tweet)
The Reflecting Rheum: Top Publications from 2020 Covering SpA and Still’s Disease Sponsored by Novartis Medical Affairs Listen to a panel of experts share their views on top spondyloarthritis and Still’s disease publications from 2020. View Now: https://t.co/Kp2drDS1x3 https://t.co/Y1PilF0Syg

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Dr. John Cush RheumNow ( View Tweet)
From Dr. Petryna ( @DrPetryna ) on Pneumonia & RA #RNL2021 : -PNA most common hospital inf in RA and main cause of hosp mortality -seropositivity assoc w/increase risk of PNA -COPD+RA bad combo: increase PNA & mortality #RheumNow https://t.co/IgXfJTMrcn
Dr. John Cush RheumNow ( View Tweet)
Have you listened to this week's podcast? Dr. Jack Cush reviews the news, FDA Denials and journal articles from the past week on RheumNow. Download wherever podcasts are available. https://t.co/Twy04G9RU1 https://t.co/NSsR2tFq5i

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Dr. John Cush RheumNow ( View Tweet)
Metanalysis of 32 studies shows most forms of arthritis assoc w/ incr risk of CVA (ischemic stroke: RR=1.53 or hemorrhagic stroke: RR=1.45), esp for RA (RR=1.38), AS (RR=1.49), PsA (RR=1.33), gout (RR=1.4) --risk higher with age <45 years (RR=1.46) https://t.co/YDiebrqtbi

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Dr. John Cush RheumNow ( View Tweet)

From @KDAO2011 for #RNL2021 Is it better to taper the steroids or leave it? SEMIRA study. Tapering off low dose steroids cause more flares and more treatment side effects. Dr. Buttgereit says keep your low dose steroids (prednisone 5 mg/day or less) https://t.co/FpQnxUKWwF

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Dr. John Cush RheumNow ( View Tweet)

News Feature: Serious Infections Still Common in Vasculitis Serious infections occurred more frequently among patients with ANCA-associated vasculitis who were given induction therapy with cyclophosphamide compared with rituximab (Rituxan). #RheumNow https://t.co/dTL6cReg8s https://t.co/U2sbEzd5DX

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Dr. John Cush RheumNow ( View Tweet)
2127 suspected myositis patients assayed for myositis Abs, ~1% tested positive for SAE Abs (small ubiquitin-like modifier (SUMO) activating enzyme) - present w/ rash first, followed by myositis, extramuscular involvement, sm risk for coincident cancer https://t.co/1f0GTcpdIo

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Dr. John Cush RheumNow ( View Tweet)

2020 Year in Review - Top Publications in SpA and Still’s Disease Sponsored by Novartis Medical Affairs Listen to medical experts discuss their latest insights in spondyloarthritis and Still’s disease. View Now: https://t.co/Kp2drDAqFv https://t.co/SQAwq84O8y

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Dr. John Cush RheumNow ( View Tweet)
Congratulations to the NIH's John J. O’Shea, M.D., who has been awarded NIAMS Harrington Prize for Innovation in Medicine. Dr. O’Shea is a scientific director at NIAMS and receives the Harrington Prize for his work on the rold of Janus Kinase https://t.co/lUbWKMrdiU

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Dr. John Cush RheumNow ( View Tweet)

A prevention trial shows atorvastatin failed to prevent RA onset - 62 pts with preclinical RA (arthralgia, +CCP/RF) randomized to PBO or statin. After 14 mos, arthritis developed in 29% with atorvastatin and 19% with placebo. https://t.co/HikuDkwNu7 https://t.co/QyGy81lgcq

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Dr. John Cush RheumNow ( View Tweet)
“Give as much glucocorticoids as necessary but as little as possible!” – Dr. F Buttgereit #RNL2021 #RheumNow Original tweet from Dr. Kathryn Dao @KDAO2011

Dr. John Cush RheumNow ( View Tweet)

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