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An evaluation of a common psoriasis drug's effect on one cardiometabolic risk factor instead showed a favorable impact on a different one.
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Dr. John Cush
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Review of 5 trials shows ixekizumab with higher rates of complete skin & nail clearance compared H2H against to etanercept, guselkumab, ustekinumab, and adalimumab (Data from IXORA-R, IXORA-S, UNCOVER-2, UNCOVER-3, & SPIRIT-H2H trials https://t.co/1JjsDTZX57 #PsA #PsAlways https://t.co/H3AM4Nn2I0
Dr. John Cush
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Towards More Uniform Methotrexate Dosing in Psoriasis
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Dr. John Cush
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ICYMI: Your Rheumatoid Questions from RNL 2022
Rheumatologists questions for Dr. Jack Cush QD
Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022
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Dr. John Cush
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Study of 221 active RA pts starting a DMARD showed that Sleep disturbance significantly predicted subsequent pain sensitization and conditioned pain modulation. https://t.co/zcUVaMemXN https://t.co/5timIb0aeG
Dr. John Cush
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ICYMI: Your Lupus Questions from RNL 2022
Rheumatologists questions for Dr. Jack Cush
QD Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022
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Dr. John Cush
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ICYMI: Japanese study using Mendelian randomization (MR) analysis of the association between coffee consumption, gout & uric acid levels - showing coffee consumption can causally reduce gout risk (OR = 0.50), independent of SUA levels https://t.co/aTGkbKDXMg https://t.co/fJqS4nxvDs
Dr. John Cush
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ICYMI: Study of 1899 ankylosing spondylitis pts(10 RCTs) shows TNFi resp can be predicted - 34% had major resp vs 34% w/ no resp @ wk12. A major resp increased w/ higher CRP, Pt Global & BASDAI-Q2 score & decr w/ higher BMI & BASFI https://t.co/Zo0PFiV3ro https://t.co/FsIiAaykpC
Dr. John Cush
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ICYMI: Free Teaching PDF on "What is Rheumatoid Arthritis" from JAMA https://t.co/gf2TBv3AjD
Dr. John Cush
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ICYMI: Study of 119 SLE pts (30 w CKD) shows urinary galectin-3 binding protein as a biomarker, increased w/ active LN, significantly (p<0.001)correlating w/ SLEDAI, SLICC RAS, histologic activity; higher in proliferative vs membranous LN (p=0.04) https://t.co/uUfwJm7JbE https://t.co/mh61wlBN87
Dr. John Cush
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ICYMI: Infection in lupus is suggested by v. high CRP, PMN-lymph ratio (NLR) Plt-lymph ratio(PLR). Study of 104 hospitalized SLE found all v.high w/ infx & Combined cutoffs of CRP >20 mg/L, NLR >3.5, PLR >151 had 87 sensitivity & 81% specificity for infx https://t.co/OOd5Mftnhl https://t.co/GqSI7HLsbY
Dr. John Cush
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Join us for Tuesday Night Rheumatology on April 5 at 7pm ET.
Register today!
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Dr. John Cush
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PsA All the Way – All April Long
Join us all April long for our focus on PsA. Tweets, articles, blogs, therapeutic updates and more...all this month!
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Dr. John Cush
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Your Hot Topic Questions from RNL 2022
Rheumatologists questions for Dr. Jack Cush
QD Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022
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Dr. John Cush
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Increased Cancer Risk with Autoimmune Disorders (AID)
The incidence and mortality of cancer among AID was studied in a large Chinese cohort, demonstrating that while onset time and risks vary, there is an increased risk of malignancy in AID.
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Dr. John Cush
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Heart Risks Elevated in RA Patients Despite Biologic Tx
Hopes that biologic drugs for RA would cancel the extra cardiovascular risks normally seen with the disease dimmed a little in the face of findings from a population-based study from Scandinavia.
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Dr. John Cush
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RheumNow's PsA Campaign with enhanced coverage of Psoriatic Disease is sponsored by Janssen. All content is chosen by RheumNow + its faculty. #PsAlways https://t.co/sjwVaNjK6x
Dr. John Cush
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Systematic lit review of 5694 CTD pts (SLE, RA, IIM, SSc) admitted to the ICU shows overall risk of mortality was 33%. ICU admits mainly for sepsis (43%), flares(40%). Mortality risk was 70% in IIM, 40% SSc, 35% SLE subgroup, 20% RA. https://t.co/ubVujkLCNy https://t.co/nnJdO36imK
Dr. John Cush
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Retrospective cohort hospital study of 228 children with MIS-C; 215 patients (median age 8 yrs, 63% boys) shows that orticosteroid monotherapy is a reasonable management option for a subset of patients with MIS-C, particularly those with mild disease https://t.co/HLSR5zOseU https://t.co/5z7I9SVcxI
Dr. John Cush
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#PsA Biologic initiation was associated with a SMALL drop in NSAIDs (51.1 to 42.5%); glucocorticoids (57.4 to 46.9%) and opioids (38.1 to 33.8%) (Initial vs 12 mos later). Pain Rx use study in 5681 PsA, 2180 AS, & 34,047 RA pts #PsAlways https://t.co/wyrT9CVNq8 https://t.co/8vl7e2a63n
