Article
Arthritis & Rheumatology has publish an ACR Subcommittee report on how the COVID-19 pandemic affected fellows and their training.
All News
Article
Tumor necrosis factor (TNF) inhibitors for rheumatoid arthritis were linked with a lower risk of Alzheimer's disease and related dementia, but only in people with cardiovascular disease, data from the DREAM (Drug Repurposing for Effective Alzheimer's Medicines) study showed.
Dr. John Cush
Tweet
Combined Clinics for PsA
Rheums and derms have long worked together in the management of our patients, but the idea of directly collaborating in a single clinic space was novel at the time. Over the years, it has become my favorite clinic of the week.
https://t.co/uY1mZtlvaV https://t.co/5AZ2z2kSVG
Dr. John Cush
Tweet
Comparison of Tofa, ADA, PBO in OPAL #PSA studies - median time to HAQ response better for Tofa & ADA (30d) vs PBO (>112d), but Tofa had faster Fatigue response (31 vs 90+D). MDA response time same between Tofa v ADA #PSAlways https://t.co/f48Of7bEjN https://t.co/KvfQUbLwCH
Dr. John Cush
Tweet
NPF COVID-19 report from AAD mtg shows #PSA pts on systemic Rx were not at risk of hospitalization or severe COVID-1 based on US claims data. Also TNFi, IL-17, IL-23 Rx not affect on Vax Ab responses; less hosp (36%) w/ TNFi https://t.co/ekvu0mMvrn https://t.co/Qogm1Vx5hF
Dr. John Cush
Tweet
How long does a good response last to a biologic?
How and When to distinguish between flares and intercurrent illness.
QD Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022
https://t.co/ZIWQysY5dd https://t.co/RZrS6FfUTV
Dr. John Cush
Tweet
SLE study from BC, Canada shows that among 3062 incident #SLE patients 96% received antimalarial (AM) Rx with only 40% adherent. Over a 6.4 yr F/U, 242 (8%) died. AM adherence was assoc w/ a 71% and 83% lower risk of death https://t.co/S9LsDaSZNx https://t.co/lFWZJTh367
Dr. John Cush
Tweet
Ixekizumab in 1401 #PSA pts w/ 2248 Pt-Yrs exposure showed Serious AE in 134 pts. Most common AEs were nasopharyngitis & URI. Incidence of SAE (≤1.2/100PY), cancer (0.7/100PY), IBD (0.1/00PY), depression (1.6/100PY) were low. #PSAlways https://t.co/YGGj4XCQDM
Dr. John Cush
Tweet
Retrospective study of 1144 consecutive inflammatory myositis (IIM) pts shows a 2.3% risk of venous thrombolic events. 54% of VTE occurred within 6 mos of IIM Dx. Predictors included malignancy, infection, longer steroid use , higher Dz activity https://t.co/DCH4Iuy2FS https://t.co/uNc6i6L7JJ
Dr. John Cush
Tweet
Cell has a novel analysis using single-cell analysis of skin/blood from 56 controls & 97 diffuse systemic sclerosis pts, finding stromal abnormalities in LGR5+-scleroderma-assoc fibroblasts (ScAFs). ScAFs are decreased early & progressively https://t.co/Khxejd1fnq https://t.co/OrMAJnPTZt
Dr. John Cush
Tweet
ArthritisPower study of 332 #PsA pts finds patients are most bothered by joint pain, MSK pain & fatigue. Patients prefer oral, QD meds; 3/4 want Rx that improved joints vs skin; and would prefer to avoid MTX https://t.co/WYqWgoimOT https://t.co/RgGeCKrpT1
Dr. John Cush
Tweet
2020 Pt preferences survey- 137 #PsA pts most took TNFi (30%), IL-17i (20%), MTX (10%). From 2018 to 2020 a signif incr in IL-17i & PDE4 inhib. Pts want Rx for damage (80%), ADL (71%), & pain (70%) https://t.co/2dyIuQubh5 https://t.co/sFbtRj0Lbv
Dr. John Cush
Tweet
ICYMI: Deucravacitinib, TYK2 inhib, studied in phase II trial 203 active PsA pts randomised to PBO, or DEUC 6 mg or 12 mg qd. At wk 16 ACR-20 responses were significantly higher with DEUC 6mg (53%, p=0.0134) and 12 mg (63%, p=0.0004) vs PBO. https://t.co/UOPteZY0g8 https://t.co/Xw3ZSPWeE0
Dr. John Cush
Tweet
ICYMI: Differences between Palpated & Ultrasound Joint exams in 155 #PSA patients. 5616 joints - found 18.5% tender, 9.8% swollen, 20.4% w/ US GS ≥ 2 and 5.2% had US PD ≥ 1. Joints that were both tender and swollen more likely to have GS ≥ (44%) https://t.co/M6y5Gezhjs https://t.co/HYoI3pExRm
Dr. John Cush
Tweet
ICYMI:The Enthesitis Challenge in Psoriatic Arthritis
A colleague of mine told me an interesting story about how her father, who was a doctor, misdiagnosed his wife with fibromyalgia when she actually had PsA with enthesitis all along.
Read more...
https://t.co/bSYdtlL41J https://t.co/gKKdWTvyMB
Dr. John Cush
Tweet
ICYMI: TNR Recap: What Patients Say About PsA
Watch Tuesday Nite Rheumatology, held on 4/5/22,which featured a Patient Perspectives panel discussion, hosted by Dr. Jack Cush.
PsA Panelists included:
- Tena Brown
- Christine Lindsay
- Ashley Krivohlavek
https://t.co/FyjnzrtKqp https://t.co/uEHsoAwHLY
Dr. John Cush
Tweet
ICYMI: Dactylitis Indicates a Severe PsA Phenotype
https://t.co/7VVoc0f1Ap https://t.co/uZxfqLvtcp
Dr. John Cush
Tweet
ICYMI: 520 RA pts were screened with FibroScan (liver fibrosis)- F3 or F4 liver fibrosis seen 13.3% of controls vs 12.7% arthritis pts. MTX was not significantly correlated w/ higher FS scores. Liver stiffness was correlated w/ BMI, waist, male , age. https://t.co/PxrabHROPy https://t.co/UAw51Hb5vU
TheDaoIndex
Tweet
Humbled to lecture at the #StaabSymposium with rheum greats @RheumNow and @KeithReich3 https://t.co/RHM1oneIc3
TheDaoIndex
Tweet
What I learned... always get an ALP and phosphorus level in people with chronic bony pain. https://t.co/nE0xYwODmC
