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Study of 351 SLE patients from Leiden shows that SLE with Neuropsychatric disease do not have a higher mortality than lupus without CNS disease; but do have higher mortality than gen. population #ACR20 Abstr#1264 https://t.co/CmBjfUj1Ur https://t.co/WYZQDaI4yt
Dr. John Cush RheumNow ( View Tweet)
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This study identified novel RFs for RA-ILD:
Obesity
⬆CRP(≥10mg/L)
Poor function(MDHAQ ≥1)
High education
30py smoking hx assoc'd w/⬆ RA-ILD risk
Do u counsel RA pts on smoking cessation & lifestyle change? @Rheumnow #ACR20 abs1198 #ACRbest @jeffsparks https://t.co/jvZ26n8k5p
sheila RHEUMarampa ( View Tweet)
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Retrospective analysis of🤰outcomes in ILD:
Live births (77%), no maternal deaths, ⬇ rates of cardiopulmonary complications.
limitations: small # of severe ILD
Multidisciplinary approach important
@RheumNow #ACR20 abs1446 https://t.co/3ayZv4XsOT
sheila RHEUMarampa ( View Tweet)
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Who will clot in #Lupus? 150 with SLE, clots ^ if PC4d + = market of plt Activation & arterial thrombosis abstr#1510 needs validation in another SLE group. V interesting @RheumNow @CRASCRRheum #ACR20 https://t.co/UBGxaFwhwZ
Janet Pope Janetbirdope ( View Tweet)
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ACR/AF JIA guidelines presented @ACR20:
👉Initiate DMARD early over NSAID monotherapy
👉Use SQ MTX> oral MTX > SSZ/LEF
👉add biologic preferred over triple DMARD
👉DON'T use chronic low dose steroids
👉combo biologic+DMARD > biologic monoRx
https://t.co/lwoFSTuV91
@rheumnow https://t.co/wzh2LCS0dN
k dao KDAO2011 ( View Tweet)
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Study incl 1243 #SLE patients finds excess risk of #cardiovascular events is underestimated by CVD prediction tools- the underestimation may be increased in those with more severe disease activity.
Abs#1286 #ACR20 @RheumNow
https://t.co/6FZvxE02CF
Mrinalini Dey DrMiniDey ( View Tweet)
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#MAS and secondary #HLH #ACR20 ABS#1150 Highlighting the use of #neopterin in following disease course and CXCL9 in active disease.- large cohort of 82 pts #IL18 marker for MAS @RheumNow #ACRbest https://t.co/166afc5Tns
Bella Mehta bella_mehta ( View Tweet)
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Great poster-abstract 1260- chicken or egg- what comes first cognitive issues for patients with SLE then the Depression/anxiety or the opposite—-mental health is so important to address!! @RheumNow #ACR20 https://t.co/3ippKQN7Ap
alexa meara lexmeara ( View Tweet)
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Undiagnosed AxSpA in IBD pts:
3k IBD pts, biologic naive
1⃣5% with axSpA after rheum eval
2⃣12 yr delay to dx
3⃣7% with PsO, 16% peripheral MSK symptoms
We need to be diligent and early in detection!
@RheumNow #ACR20 Abs#1309
Robert B Chao, MD doctorRBC ( View Tweet)
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Post-hoc analysis of RA-BUILD & RA-BEACON: Bari-2mg showed improvement in pain, physical funxn, fatigue and MJS vs. placebo for both csDMARD-IR & bDMARD-IR @RheumNow #ACR20 abs1228 https://t.co/EIDXyJEi1q
sheila RHEUMarampa ( View Tweet)
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SLE pts May have significant changes in blood brain barrier with CSF leak w changes in brain structure &cognitive function. Abstr#1508 Take #Lupus pts CNS symptoms seriously. #ACR20 #bestinclass @RheumNow @CRASCRRheum https://t.co/asgL1R9eYq
Janet Pope Janetbirdope ( View Tweet)
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The roadmap to a research career includes writing a grant. @jeffsparks explains why: @RheumNow #ACR20 https://t.co/QxqQHOytNS
sheila RHEUMarampa ( View Tweet)
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Dr @kaz_yos and @jeffsparks presenting that childhood parental smoking is associated with later sero+ RA even after adjustment for adult personal smoking Abstr#1000 #ACR20 @rheumnow https://t.co/7ZqwNluwaP
Richard Conway RichardPAConway ( View Tweet)
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Dr Joshua presents that citrulline-reactive B cells producing pathogenic ACPAs are present in the lungs of seropositive patients with arthralgia or early RA. Supports lung as key site of initiation of RA. @rheumnow #ACR20 Abstr#1445 #ACRbest https://t.co/PBZJdQo2M9
Richard Conway RichardPAConway ( View Tweet)
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Gout has high multimorbidity burden in #RISE registry, gout has more cormorbidities than RA & PsA and OA has the least & the assoc diseases are different too. Abstr#1466 @RheumNow @CRASCRRheum #ACR20 https://t.co/qPogonxDSB
Janet Pope Janetbirdope ( View Tweet)
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@LeslieCrofford on building a successful career:
> priority-setting is essential
> no shortcuts to career advancement
> set your goals & prioritize your efforts
> be kind
@RheumNow #ACR20 https://t.co/G0V2IY6b4Z
sheila RHEUMarampa ( View Tweet)
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Lucio phenom: a hallmark of leprosy w/erythem macules & necrotic hemorrhagic blisters that ulcerate, scar; vasculitis w/thrombus formation and endothelial proliferation can occur
#ACR20 Thieves Market Abstr#TM02: "The Dz of the Soul" ref. medieval assc w/moral turpitude @rheumnow https://t.co/YQwGphBhFC
k dao KDAO2011 ( View Tweet)
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Stimulating the vagus nerve with an auricular device decreases joint inflammation and clinical symptoms in painful erosive hand osteoarthritis: the first proof-of-concept trial. Courties et al. #ACR20 >FB https://t.co/RD9xTfjjCd
ARD & RMD Open ARD_BMJ ( View Tweet)
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Pain in Women with Knee and/or Hip Osteoarthritis Is Related to Systemic Inflammation and to Adipose Tissue Dysfunction and Distribution: A Cross-sectional Metabolic Biomarkers Cohort Study. Sellam et al. #ACR20 >FB https://t.co/iIdrglAilW
ARD & RMD Open ARD_BMJ ( View Tweet)
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#ACR20 Abstract#1001, we report "no difference in the risk of skin cancer including malignant melanoma and NMSC among older RA patients initiating MTX or HCQ as their 1st DMARD, but risk of BCC higher in MTX compared with HCQ". @Rishidesai11 @BrighamResearch @MengdongHe https://t.co/r3tLCt5LsR
Seoyoung C. Kim SeoyoungCKim ( View Tweet)