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Spondyloarthritis at ACR Convergence 2020

Antoni Chan, MD, PhD

There are some really interesting poster and abstract presentations on spondyloarthritis at the ACR Convergence 2020. I’ll be covering these topics, and discussing select individual posters and abstracts during this meeting. 

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RheumNow’s expanded coverage of the #ACR20 Annual meeting is sponsored in part by Novartis. All content chosen by @RheumNow and its Faculty.

Dr. John Cush RheumNow ( View Tweet)

Baseline characteristics differed between M/F pts w/ AS & nr-axSpA. Women were older at dz onset w/longer symptom duration & more joint dz and were less likely to be + HLA-B27 than men. Do you see this in your practice? #ABS0876 #ACR20 @RheumNow https://t.co/2goek1NiUW https://t.co/Uk8pmNP4Hr

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Dr. Rachel Tate uptoTate ( View Tweet)
Pooled analysis from MEASURE 1-5 showed SEC was effective for AS regardless of HLA-B27 status. HLA-B27+ pts had more therapeutic benefit vs. HLA-B27- pts. @RheumNow #ACR20 abs#0885 #ACRbest https://t.co/eD3ZGWxDkX
sheila RHEUMarampa ( View Tweet)
New treatments in Axial Spa at #ACR20. A significantly higher proportion of pts receiving Upadactinib vs placebo achieved reductions in all PGA of pain assessments and sustained to week 64 @RheumNow Abstr#369

Dr. Antoni Chan synovialjoints ( View Tweet)

Secukinumab has been used to treat spinal involvement in axial SpA. Secukinumab led to significant improvements in symptoms of peripheral arthritis in pts with AS. Significant improvements were seen in both tender and swollen joints @RheumNow #ACR20 Abstr#366

Dr. Antoni Chan synovialjoints ( View Tweet)

Check out my video on @rheumnow! #ACR20 Non-radiographic axSpa ACR Abstracts: Dr. Rachel Tate https://t.co/TVDdyZvOEA via @YouTube

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Dr. Rachel Tate uptoTate ( View Tweet)

RheumNow’s expanded coverage of the #ACR20 Annual meeting is sponsored in part by @Novartis. All content chosen by RheumNow & its Faculty.

Dr. John Cush RheumNow ( View Tweet)

Better outcomes (ASAS20 and ASAS40 @wk 52) seen in younger pts (possibly lower disease duration) when Secukinumab was given to ankylosing spondylitis pts. Early Dx in #AS! #ACR20 Abstr#0350 https://t.co/EKks0b1upc https://t.co/bxIH9lloI1

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Dr. John Cush RheumNow ( View Tweet)
Emerging trend #MachineLearning - SpA expert Dr Dennis Poddubnyy talks at #ACR20 press conference - Development and Validation of an #artificial_intelligence Approach for the Detection of Radiographic Sacroiliitis using MRI @RheumNow

Bella Mehta bella_mehta ( View Tweet)

Who will be more likely to have chronic reactive arthritis @RheumNow #ACR20 @CRASCRRheum

Janet Pope Janetbirdope ( View Tweet)

ACHILLES study: Only 56% of pts w/ clinical enthesitis had MRI+ heel enthesitis. MRI screening: HLAB27+ pts likely to be in MRI+ grp. @RheumNow #ACR20 Abstr#0447 #ACRbest https://t.co/m2cjDzYfyg
sheila RHEUMarampa ( View Tweet)
Dr.Gonzalez-Mazon describes surrogate markers assoc'd w #atherosclerosis in #axSpA: BASFI, BASMI, IBD, ESR, CRP, prednisone and DMARDs use. @RheumNow #ACR20 abst#0448 https://t.co/g27qA4qpPL
sheila RHEUMarampa ( View Tweet)

Extended 5 year study of secukinumab in AS patients showed sustained improvement of back pain, nocturnal back pain, AM stiffness, fatigue and LDA Abs#0364 @RheumNow #ACR20

Robert B Chao, MD doctorRBC ( View Tweet)

RheumNow’s expanded coverage of the #ACR20 Annual meeting is sponsored in part by BMS, @HorizonNews , @SanofiGenzyme, @Novartis. All content chosen by RheumNow & its Faculty.

Dr. John Cush RheumNow ( View Tweet)

"Anatomy of the enthesis" #SpA #ACR20 https://t.co/uUeCWGXqtw
Julio Gonzalez japaoli19 ( View Tweet)
Dr. C. Bakewell reminds us that entheses can show inflammation and chronic changes. Pearl: Be sure to look at MSUS of the digits for enthesitis. #ACR20 #ACRbest @RheumNow https://t.co/D3nLGGv4ko
Dr. Rachel Tate uptoTate ( View Tweet)
Vaccinate your pts against pneumococcal- it works! 595 vaccinated pts with RA & SpA vs 2379 nonvaccinated followed to 10 yrs showed 50% less pneumonia if vaccinated even though those pts had more infections prior. Limitation not RCT & not vaccine I use @RheumNow @CRASCRRheum https://t.co/SySEL19Gcn
Janet Pope Janetbirdope ( View Tweet)
New drug mechanisms for SpA. Nice to have expanding options #ACR20 https://t.co/vlTwaiuuS3
Dr Irwin Lim _connectedcare ( View Tweet)
Tofacitinib for the Treatment of Adult Patients with Ankylosing Spondylitis: Primary Analysis of a Phase 3, Randomized, Double-blind, Placebo-controlled Study https://t.co/F86K1Lqou7 #tofacitinib #AS Tofa works in AS , zoster no VTE seen NNH 20(per SAE) NNT 2.5(per ASAS40)

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Peter Nash drpnash ( View Tweet)

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