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Diagnostic Delay in Psoriatic Arthritis: What are the Consequences?

d Olga Petryna, MD

Despite increased awareness and better diagnostic modalities at hand, early diagnosis of psoriatic arthritis (PsA) still remains a huge unmet need.

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Secukinumab in Psoriatic Arthritis Patients with Axial Disease

d Sheila Reyes, MD

Results of the MAXIMISE trial show that Secukinumab provided clinical improvement and reduction in inflammatory MRI lesions in patients with psoriatic arthritis and axial disease through week 52. 

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Dr Christ reports on GUSTO study showing that 13/18 GCA patients treated with tocilizumab and only 3 days of steroid maintained remission at 24 weeks. @rheumnow #ACR20 Abstr#515 #ACRbest https://t.co/VLgXEUIi1c
Richard Conway RichardPAConway ( View Tweet)
Which has better durability in RA? @RheumNow @CRASCRRheum #ACR20 abstr#222

Janet Pope Janetbirdope ( View Tweet)

If the presence of fibromyalgia correlates with clinical outcome scores in psoriatic arthritis (PsA), how do you differentiate between fibromyalgia and PsA disease activity? @RheumNow #ACR20

Dr. Antoni Chan synovialjoints ( View Tweet)

Looking forward to the "#COVID19 Around the World: Impact on #Rheumatology" session over the next hour- amazing to be reminded that @rheum_covid Global Rheumatology Alliance started with a tweet! 😀 #ACR20 @RheumNow https://t.co/t2yPfkz2Cb
Mrinalini Dey DrMiniDey ( View Tweet)
Dr Quinn presenting on tocilizumab effects on PET in GCA. Abstr#514 @rheumnow #ACR20 My concern is this, persistent low grade activity on toc that returns on stopping https://t.co/nB0C1AEjbN
Richard Conway RichardPAConway ( View Tweet)
Save your $ as starting ERA with MTX works vs initial bDMARD. 470 w ERA given Rx based on DAS. Strategies MTX, BDMARD, one to other or vice versa. Not RCT- if not needed to stepup you did well as did stepdown. Not a #gamechanger @RheumNow @CRASCRRheum abstr#221 #ACR20 https://t.co/o1L3LlpIlm
Janet Pope Janetbirdope ( View Tweet)
Ultrasound in PsA: PsA pts with fibromyalgia were associated with higher non-MDA, CPDAI, PASDAS scores but NOT higher US scores of the joints, tendons, and entheses. @RheumNow #ACR20 #ACRbest Abs#0315 https://t.co/dapIk1rWQm
Robert B Chao, MD doctorRBC ( View Tweet)

If the synovio-entheseal complex is important in the pathogenesis of psoriatic arthritis, how do you assess the entheses in clinic? @RheumNow #ACR20

Dr. Antoni Chan synovialjoints ( View Tweet)

Another interesting study demonstrating the use of ultrasound to assess psoriatic arthritis. In very early, DMARD naïve PsA, clinically swollen joints are associated with PD synovitis, but tender, non-swollen joints are not @RheumNow #ACR20 Abst#313

Dr. Antoni Chan synovialjoints ( View Tweet)

Following promising data presented at today's poster session, results from RELIEF #Behcets study show #apremilast leads to ↓ rates of new/recurrent/worsening oral ulcers, skin lesions & #arthritis compared to placebo at 12wks. Abs#0512 #ACR20 @RheumNow https://t.co/O1dstY5WlL https://t.co/0djnUGw0Hg

Links:

Mrinalini Dey DrMiniDey ( View Tweet)
Another study on rheum pt outcomes w/#COVID19: similar outcomes as nonrheum pts. MGH/JHU/Brigham 143 rheum vs 688 nonrheum. No⬆️risk in rheums after adjusting for race/smoking/comorbidities for: hospitalizations, mech ventil'n 3. ICU 4. death #ACR20 Abstr#L01 @RheumNow https://t.co/362UZUe5dg
k dao KDAO2011 ( View Tweet)
Prof Hatemi report on apremilast in Behcets disease. We know it improves oral ulcers. Now shown to improve skin lesions and arthritis. @rheumnow #ACR20 Abstr#512 https://t.co/BwIqio6dzq
Richard Conway RichardPAConway ( View Tweet)

DISCOVER-2 (52 wk study) Guselkumab 100mg q4wk and q8wk for tx of PsA 1️⃣Sustained responses in: ACR20/50/70, PASI90/100, HAQ-DI, MDA/VLDA, QoL 2️⃣Improvement enthesitis/dactylitis 3️⃣No increase rate of serious infection @RheumNow #ACR20 Abs#0506 https://t.co/7MXYTucVZ9

Robert B Chao, MD doctorRBC ( View Tweet)
The presence of fibromyalgia in psoriatic arthritis correlates with the clinical outcome scores. Ultrasound evaluation can be useful to evaluate disease activity in the presence of fibromyalgia @rheumnow #ACR20 Abstr#315 #ACRbest

Dr. Antoni Chan synovialjoints ( View Tweet)

“Rheumatology comes in as the #2 specialty utilizing teleheath in a survey by Doximity.” Dr. C. Peoples discussing teleheath and COVID-19. “The elephant in the room is the physical exam!” #ACR20 @RheumNow

Dr. Rachel Tate uptoTate ( View Tweet)

How do you treat ACPA+, subclinical synovitis (US/MRI+)? Abst#0481 reviews 3 cohorts for progression to clinical inflam arthritis. 44-68% did not progress to IA in 1 year, is DMARD over treating? #ACR20 #ACRBest @RheumNow

Eric Dein ejdein1 ( View Tweet)

Dr. Phillips touches on a few things to consider how teleheath has changed the delivery of care due to COVID-19. Planning your post-pandemic business strategy, due demand for our specialty, is important. #ACR20 @RheumNow https://t.co/A2dsVy1KSg
Dr. Rachel Tate uptoTate ( View Tweet)
Dr. C Mohan @UTSWNews #ACR20 @rheumnow reviews IFN in SLE: 👉Diff't IFN assc w/diff't lupus manifestions 👉⬆️stim endosomal DNA/RNA sensors RLR7,8,9 may drive SLE 👉TLR7 & 9 in B cells impt for germinal ctrs & Ab prod’n 👉TLR7 is X-linked 👉IFNsig not track w/dz activity https://t.co/3KK3UvH8Ka
k dao KDAO2011 ( View Tweet)

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