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Data from MUSE & TULIP trials of #anifrolumab in #SLE show increased risk of #herpeszoster when compared to placebo. Most HZ events mild-moderate, cutaneous and resolved without discontinuation of drug.
#RheumTwitter #lupus
Abs#0849 #ACR20 @RheumNow
https://t.co/8a6OcZmOso
Mrinalini Dey DrMiniDey ( View Tweet)
The development of biologics started with diphtheria- history of Medicine! Look how far we have come now prescribing over 50 different types of biologics! @RheumNow #acr20 https://t.co/XbygK5g7ON
alexa meara lexmeara ( View Tweet)
BKZ tx improved BASDAI total and single question scores related to fatigue and neck, back and hip pain in pts with PsA. #ABS0906 #ACR20 @RheumNow https://t.co/GzpJfkwvL5 https://t.co/KnJAqAKlqq
Dr. Rachel Tate uptoTate ( View Tweet)
Do pts with RA take their meds & can adherence intervention work? Yes & No. Pts starting new bDMARD RCT of electronic monitoring feedback vs usual care, adherence>80%. Neg RCT Maybe chronic users with poor adherence is group to study abstr#0799 #ACR2020 @RheumNow https://t.co/FyWoBjYnvs
Janet Pope Janetbirdope ( View Tweet)
Valerio et al find 40% of 294 patients w/ #rheumaticdisease refuse or are uncertain about getting inactivated #influenza #vaccine. Key determinants of #vaccinehesitancy found to be concerns about adverse events, safety & efficacy.
Abs#0632 #ACR20 @RheumNow
https://t.co/f34DAc5WiN
Mrinalini Dey DrMiniDey ( View Tweet)
Do you consistently address T2T in your axSpA patients in your clinical practice? List your measures below! #ACR20 @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)
Which Adalimumab biosimilar to use (if any)? The race is on to have 1st Ada or 2nd reimbursed/preferentially listed in US reimbursement plans & dare I say it mandatory switching like in Europe. Abstr#0798 #ACR2020 compares Abrilada & Humira in RA @RheumNow @CRASCRRheum https://t.co/AUcVZnc6Gj
Janet Pope Janetbirdope ( View Tweet)
In the search for biomarkers in PsA, interesting study showing absolute lymphocyte count is negatively correlated with cardiovascular disease risk score and red cell distribution width and increases with TNF-Inhibitor Therapy @rheumnow #ACR20 Abstr#878
Dr. Antoni Chan synovialjoints ( View Tweet)
Some great abstracts on #vaccine hesitancy in the #infection in #rheumaticdiseases poster session!
What's the greatest concern for patients offered #influenza & #pneumococcal vaccines?
How can we address these concerns & encourage vaccine uptake? Comment below!
#ACR20 @RheumNow
Mrinalini Dey DrMiniDey ( View Tweet)
T2T in clinical practice: Most axSpA pts had ≥1 annual ASDAS recorded, but target ID/LDA achieved in only 1/3 of pts at the first measurement. How do you address T2T in your practice? #ABS0879 #ACR20 @RheumNow https://t.co/Jy0mmqpHAb https://t.co/06fI10V3OZ
Dr. Rachel Tate uptoTate ( View Tweet)
Great job by @Rheumnow's Dr. Jonathan Kay on CT-P17, ADA biosimilar in Abst#0800. Similar ACR20 83% rate for ADA and CT-P17 with similar safety profile. #ACR20.
Eric Dein ejdein1 ( View Tweet)
Lots at #ACR20 on arthralgias w/ +CCP. Abst#760 shows bone erosions (BE) rare in these pts (4%), did not show higher risk of progression to IA (41% w BE vs 31% wo BE, p=0.4). Overall high progression, unclear if high enough # with BE for analysis. @RheumNow.
Eric Dein ejdein1 ( View Tweet)
Tracking CRP in the hyper-acute phase of admission for #COVID19 predictive of progression to critical illness- suggests trends of inflammatory biomarkers, not absolute admission values, may be most useful for triage & therapy.
Abs#0626 #ACR20 @RheumNow
https://t.co/E14y3e4ALi
Mrinalini Dey DrMiniDey ( View Tweet)
Dr. J. Walsh slide on PROs in PsA research. #ACR20 @RheumNow https://t.co/v4ufUdWufB
Dr. Rachel Tate uptoTate ( View Tweet)
RheumNow’s expanded coverage of the #ACR20 Annual meeting is sponsored in part by Novartis. All content chosen by @RheumNow and its Faculty.
Dr. John Cush RheumNow ( View Tweet)
What is your initial csDMARD of choice in pts w/ elderly-onset RA? @RheumNow #ACR20
sheila RHEUMarampa ( View Tweet)
Baseline characteristics differed between M/F pts w/ AS & nr-axSpA. Women were older at dz onset w/longer symptom duration & more joint dz and were less likely to be + HLA-B27 than men. Do you see this in your practice? #ABS0876 #ACR20 @RheumNow https://t.co/2goek1NiUW https://t.co/Uk8pmNP4Hr
Dr. Rachel Tate uptoTate ( View Tweet)
Patients with ARDs have incr. susceptibility to #infection. Real-world study shows suboptimal #influenza, #pneumococcal & #herpeszoster #vaccination coverage in these patients. Important to consider strategies to improve uptake.
Abs#0541 #ACR20 @RheumNow
https://t.co/GAapkzILvW
Mrinalini Dey DrMiniDey ( View Tweet)
Dr Peral reports on intracellular crystal containing vacuoles in gout and CPP arthritis. Crystal containing vacuoles only seen in CPP arthritis. @rheumnow #ACR20 Abstr#666 https://t.co/ITQMXhjQt0
Richard Conway RichardPAConway ( View Tweet)
Serial RF titers? Abst#0754 from Japan: Pts with RF>45, tracked RF at month 0/4/12 after starting b/tsDMARD. 46/130 had RF decrease titers, had better radiographic remission/DAS28-ESR. Limits: varied Rx, More aggressive Rx w RF decrease grp @RheumNow. #ACR20
Eric Dein ejdein1 ( View Tweet)