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Inflammation is not a single entity, and the imperative to dissect it carefully is so great in irAEs - in both treatment and measurement.
"I'm attempting to stir the pot" - @LCalabreseDO
- and there really is plenty to think about. https://t.co/8C6RbMI2l9
David Liew drdavidliew ( View Tweet)
One of my #ACR20 highlights about to start - irAE Study Group, hosted by @CCalabreseDO & @NohaMDAnderson
Imminent paradigm definition by @LCalabreseDO: one of the biggest challenges in the field: how to target therapies in irAEs, to maintain cancer response
#ACR2020 @RheumNow https://t.co/WzFbCc8TuT
David Liew drdavidliew ( View Tweet)
Just the beginning... trained over 1397 x-rays, this will only get better.
It could either:
- stop humans from having to do tedious things
- make Sharp/SvdH scores readily available in clinical practice/developing world/consistent in studies.
Either way, good!
tag @DrCMcMaster
David Liew drdavidliew ( View Tweet)
Concise, educational and useful table by @ArleneBravoMD presented by Dr. Arthur Kavanaugh in his PsA clinical trials update.
Beautiful organization of targeted therapy in multiple autoimmune diseases.
Bedside to Bench. @RheumNow #ACR20 https://t.co/PIvvsQWs0J
Robert B Chao, MD doctorRBC ( View Tweet)
Dr. Siri will see you now...🤖
Machine learning identified 9 signatures including nail pso, CRP and 7 biomarkers to distinguish PsA from PsO pts without arthritis and will help diagnose PsA early.
➡️will need to test independent data
@RheumNow #ACR20 Abs#0502
Robert B Chao, MD doctorRBC ( View Tweet)
Abst#0194 at #ACR20 showed that significant symptoms of depression in RA are more frequent than depression diagnosed clinically, suggesting that depression may go undiagnosed and that symptoms of depression predicted mortality in RA patients! @RheumNow https://t.co/GqwXNB45y2
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Totally down by this but...
what to do about about SSZ??? ( I don't use it anymore but the data are weird).... @philipcrobinson @JYazdanyMD @EBRheum @alhkim @CCalabreseDO https://t.co/kYNxxjqL2B
Leonard Calabrese LCalabreseDO ( View Tweet)
Please join #ACR20 for late breaking abstract on Ziritaxestat, selective autotaxin inhibitor. Phase 2a trial with stats significant effect on skin score and well tolerated. @UMIntMed
Session Date Monday, November 9
Presentation Time: 12:15 PM - 12:30 PM ET
Dr. Dinesh Khanna sclerodermaUM ( View Tweet)
Our paper on body composition in #PsoriaticArthritis #PsA is now published in @RheumJnl
Results show increased visceral fat in PsA similar to type 2 diabetes in @uk_biobank
Important implications for management.
@iiiglasgow @UofGICAMS @AMRAMedical
https://t.co/6vfkz78tzC
Stefan Siebert StefanSiebert1 ( View Tweet)
BSR Guidelines and best practice is the top member benefit and reason for joining @RheumatologyUK. For anyone who wants to know more about how to get involved with guideline development, this is the perfect opportunity. #MemberEngagement https://t.co/SbskxCzkmI
Erin Taylor ErinTay61017977 ( View Tweet)
Newly discovered HGF & HGFAC genes differentiate PsA and PsO in genetic analysis. Could these be important additional biomarkers for dz? #ABS0500 #ACR20 #ACRbest @RheumNow https://t.co/TNEQo6d6mk https://t.co/bQFBzYmV0J
Dr. Rachel Tate uptoTate ( View Tweet)
ACPA+ and subclinical synovitis does not automatically mean developing to RA.
Interesting work by Cleo Rogier et al. Something to consider in pts w/arthralgias & when to start csDMARDs @RheumNow #ACR20 Abstr#481 #ACRbest https://t.co/q3vIITmtq2
sheila RHEUMarampa ( View Tweet)
Lung disease in primary #SjogrensSyndrome is common; both conditions were diagnosed at the same time in 43% of patients, found an #ACR20 study from @joannamarco @GGRheumdoc + @UW @uofcincy colleagues. “Close monitoring is warranted” to make sure lung function is not declining. https://t.co/MpA0Rq2uVR
CreakyJoints.org CreakyJoints ( View Tweet)
Timezones wont stop international attendees to make #rheum for knowledge at #ACR20. Watch to see @RHEUMarampa @RichardPAConway @drdavidliew interview @DrSwamyV 🌎🌍🌏
@RheumNow https://t.co/dbIjiLhUnh
LiSa rheumarhyme ( View Tweet)
#ACR20 has a fantastic virtual platform & have put in a big effort to make the meeting friendly for international attendees.
I had a great chat about it with @DrSwamyV (@ACRheum Chair, Education) @RheumNow with @RichardPAConway @RHEUMarampa
Check it out: https://t.co/TDHg0PExBC
David Liew drdavidliew ( View Tweet)
This convinces me! #TNF inhibitors vs #JAKI
great debate at #ACR20 https://t.co/Xb8KkmDJ8f
KenWarringtonMD MdWarrington ( View Tweet)
New treatments in Axial Spa at #ACR20. A significantly higher proportion of pts receiving Upadactinib vs placebo achieved reductions in all PGA of pain assessments and sustained to week 64 @RheumNow Abstr#369
Dr. Antoni Chan synovialjoints ( View Tweet)
Secukinumab has been used to treat spinal involvement in axial SpA. Secukinumab led to significant improvements in symptoms of peripheral arthritis in pts with AS. Significant improvements were seen in both tender and swollen joints @RheumNow #ACR20 Abstr#366
Dr. Antoni Chan synovialjoints ( View Tweet)
Axial Involvement in Psoriatic Arthritis: Perspective by Dr. Eric Ruderman @JointMD
Dr. Eric Ruderman, Chicago, IL., provides his perspective on ACR 2020 coverage of axial involvement in Psoriatic Arthritis.
https://t.co/VwrQgirJnE
Dr. John Cush RheumNow ( View Tweet)
@drdavidliew @MGHrheumatology @RheumNow That is so interesting. Haptoglobin first described by Paolaggi et al in early 1980s as having potential to monitor PMR/GCA even when ESR normalised. See link here...
https://t.co/ERkhUwssox
Dr Sarah Mackie Sarah_L_Mackie ( View Tweet)