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Retrosp study in France compared MRIs of 96 pts w/ SpA (65% w/ IBP) vs 104 w/o (25% w/ IBP):
- 65% of pts w/ SpA had bone marrow edema (BME) mainly in the iliac quad of intermed middle segment
- 20% w/o SpA had BME mainly in antero-middle quad. #Abst1535 #ACR2020 @RheumNow https://t.co/1ptGGUbUS4
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)

~1/3 early RA patients report unacceptable pain w/in one year of diagnosis. 69% have pain w/ low inflammation. No objective baseline measures predict unacceptable pain. #ACR20 @RheumNow Abs#1716 We need to start pain approaches at time of diagnosis for all
Eric Dein ejdein1 ( View Tweet)

#AerobicExercise improves #Fatigue & #QualityofLife in women w/ #SLE
- ↓Fatigue & ↑overall health after exercise program
- No increase in #lupus activity
- Data may inform understanding of fatigue & exercise interventions in SLE
Abs#1838 #ACR20 @RheumNow
https://t.co/0YtYHrWp6t
Mrinalini Dey DrMiniDey ( View Tweet)

How often do you perform NFC in suspected SSc patients? @RheumNow #ACR20
sheila RHEUMarampa ( View Tweet)

@uptoTate @RheumNow It is only when I started working more closely with our rheum team to look at improving services did I realise how high no-shows are ! We have a 2yr waiting list so these appts are like gold dust. Unfortunately telemedicine not a viable option for your 1st rheum appt.
Wendy Costello wendycostello2 ( View Tweet)

Pulmonary disease and glucocorticoid usage risk factors for RA medication changes in first 3 month of #COVID19. Pts with higher reported disease activity more likely to make Rx changes #ACR20 @RheumNow. Abst#L05.
Eric Dein ejdein1 ( View Tweet)

No need to stop Tofa w/the flu?
👉Posthoc analysis 7964 Tofa pts over 14-15 flu seasons reported similar flu rates compared to ADA, MTX, PCB.
👉Tofa cont. in 70% pts; 28.8% stopped; mean days to resolution similar.
Abstr#L04 #ACR20 @rheumnow #ACRBest
https://t.co/rZXKRVl7uK
k dao KDAO2011 ( View Tweet)

Frequency and Anatomic Distribution of MRI Lesions in the Sacroiliac Joints of Healthy Subjects and Patients with Spondyloarthritis. Dr Hecquet. #ACR20 @RheumNow BME was seen in 65% patients with Spa and in 20% without spondyloarthritis predominantly in the antero-middle quadrant https://t.co/OUYz2FQ5Yp
Sole RetamozoSole ( View Tweet)

Accdg to this study, no association was found between IFN levels and cognitive function in SLE pts (even after considering factors like SLE dse duration)
Interesting! @RheumNow #ACR20 abs1788 @ZahiTouma https://t.co/F4j8H1CWJ9
sheila RHEUMarampa ( View Tweet)

Important work by Dr. Winthrop on influenza AEs in Tofacinitib patients - similar among 5mg/10mg BID, only 2 deaths/~500 cases, both with H1N1 and co-morbid RFs. Abst#L04 @RheumNow #ACR20 https://t.co/7MZYGv8W3i
Eric Dein ejdein1 ( View Tweet)

Do you have a problem with no-shows? #ABS1584 discusses telemedicine and care access during COVID-19. Case Western observed a 0% cancellation rate, <10% no-show rate, & 90% of scheduled telemed visits completed during COVID-19. #ACR20 #ACRbest @RheumNow https://t.co/uxzpfELDBG https://t.co/U2qrOTJZOq
Dr. Rachel Tate uptoTate ( View Tweet)

My axSpA patients often ask me whether whether it's the weight loss that matters, or just exercise.
Some answers from @rheum_cat - BMI itself does matter in AS. Another one chalked up for the obesity-related inflammasome!
#ACR20 ABST1883 @RheumNow https://t.co/oMOqA8ypTt
David Liew drdavidliew ( View Tweet)

Encouraging results on selective TK2 inhibitor in active PsA patients. ACR20 at week 16 of 53% and 63%, for low and high dose, compared to 32% placebo. NP, sinusitis, ha, rash most common AEs. Abst#L03 @RheumNow #ACR20 https://t.co/2UrOKFfnCL
Eric Dein ejdein1 ( View Tweet)

Evidence that patients on biologics getting COVID less frequently should be interpreted with the knowledge that Abst#L02 shows increased shielding/risk mitigation of patients on biologics #ACR20 @RheumNow https://t.co/Dn1lUtd6hl
Eric Dein ejdein1 ( View Tweet)

Abst#L01. Pt is on MTX/ADA for RA and asks you about their COVID risk. What do you counsel your patient? #ACR20 @RheumNow.
Eric Dein ejdein1 ( View Tweet)

What are you telling rheum pts their risk is for COVID? MGH: higher unadjusted rate of mech ventilation, but not signif difference after adj for co-morbidities. Encouraging temporal improvement in care seen. Abst#L01 #ACR20 @Rheumnow https://t.co/BnPCtbo5Nj
Eric Dein ejdein1 ( View Tweet)

Poster #L02 by @yatesmark1 et al shows #shielding in #IMID population on biologics may at least in part explain the lower risk of adverse #COVID19 outcomes in this group. Reinforces need for clear guidance on risk mitigation for patients.
#ACR20 @RheumNow
https://t.co/H4RMbfBrH2
Mrinalini Dey DrMiniDey ( View Tweet)

Fatigue in RA - massive burden on patients.
Intensity of fatigue in RA is a/w:
pain, psychological distress, morning stiffness
but not a/w:
ESR, CRP, swollen joint count
Fatigue needs its own consideration, separate to RA 'dx activity'!
ESPOIR cohort #ACR20 ABST1727 @RheumNow https://t.co/Uqu5LDvSV6
David Liew drdavidliew ( View Tweet)

Early RA window of opportunity: how hard, how early?
Commonsense reassurance from ESPOIR: to get good outcomes at 10y (DAS28≤2.6, HAQ≤0.5):
- csDMARD early
- bDMARD second line is okay, within first 1y+
(analysis weighted for subsequent Rx exposure)
#ACR20 ABST1717 @RheumNow https://t.co/kG9WYUYYef
David Liew drdavidliew ( View Tweet)

High-intensity interval training (HIIT) benefits RA, & it looks more than just exercise-FM-CV health.
Changes in T cell activity, muscle oxidative metabolism after HIIT in sedentary RA pts n=12
Looking forward to seeing more in this area
@dukemedicine #ACR20 ABST1757 @RheumNow https://t.co/5gKheEUYJ6
David Liew drdavidliew ( View Tweet)