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The arsenal of therapeutics for psoriatic arthritis continues to increase. Risankizumab is an IL-23 inhibitor to the p19 subunit, currently being investigated for treatment of psoriatic arthritis.
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The opening of ACR2 Convergence was a hit for all who signed up and viewed in. The day included the presidential address by outgoing president Dr. David Karp (UT Southwestern) and a keynote talk and interview with Dr. Seema Yasmin (Stanford).
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Appropriate assessment and management of comorbidities and multimorbidity in patients with RA is vital for overall health and well-being of the patient, as well as to encourage treatment adherence, and address social, psychological and quality of life factors.
Pedro Castillo
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Dr. Katie Liao presented an observational study comparing SLE pts who were Ro neg (n=208) vs Ro pos (n=185).
More of the (+)Ro pts had:
⬆️Adjusted mean SLEDIA >4
⬆️Proteinuria
⬆️Neutropenia,+RF, +dsDNA, and low C3 or C4
⬆️Discoid or malar rash
#ACR21 Abst#0323 @RheumNow
David Liew
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Fatigue fills us with dread: common, big issue, no proven meds, non-pharm Rx hard to access.
Pragmatic RCT in UK, inflamm rheum dx:
usual care v CBT v exercise program
(all remote delivery)
Clinically meaningful benefit - now how to access?
LIFT study #ACR21 ABST0462 @RheumNow https://t.co/XsSCzkbcCd
TheDaoIndex
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@JointMD shares his thoughts on IL23, IL17, TNF inh- where/when/how we might use them. @RheumNow #acr21 https://t.co/mVw05iFPhF
Dr. John Cush
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Rheumatologists and Health Professionals: Join us tonight for RheumNow's #ACR21 Daily Recap at 7pm Eastern time . Register via the Zoom link below.
https://t.co/MalO30jgo1
Or visit our YouTube channel-RheumNow.
https://t.co/nBUk64XBjU https://t.co/pYEFOM1Q2g
sheila
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Distinguishing between #preeclampsia and #lupus nephritis flare in 🤰 #SLE patients is very important because management is different. #rheumatology #medtwitter https://t.co/Dc9ohJQ75L
Janet Pope
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Blurred line btwn RA, preRA & RA prevention which makes interpretation of RCTs problematic. I’ve learned that if pt has RA not meeting criteria, some Rx ⬇️chance of RA over time-MTX, now #Abatacept but was it RA anyway AND what happens when you stop Rx? #ACR21 @RheumNow abst#0505 https://t.co/HwivsITvCQ
Elena MyasoedovaMD
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#ACR21 #Aging #CommunityHub @UnaMakris @SattuiSEMD @KWyshamMD
Very engaging discussion on the 5 Ms of aging + how they interconnect:
👉🏻multimorbidity (⬆️ risk)
👉🏻meds (poly pharmacy)
👉🏻mentation (cognitive impairment)
👉🏻mobility and disability
👉🏻what matters most <to patient> https://t.co/mZpk3qQFgz
Md Yuzaiful Md Yusof
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#ACR21 #Abstr0437 OK, so RTX affects #COVID vaccine but some pts need RTX. Factors predicting response to vaccine:
RA vs AAV/IIM
Higher IgG
Longer time-to-RTX
Lower RTX courses Number.
Prediction Calculator is developed but need ext. validation #RheumNow https://t.co/iXSaGQ76hS https://t.co/WQAV3GRPBz
Md Yuzaiful Md Yusof
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#ACR21 #Abstr0336 ANA is not a great test for #lupus diagnosis. Multianalyte Assay Panel with Cell-Bound Complement Activation Products could improve diagnosis (OR 6.3) and Drug Initiation (OR 2.8). Can we speed up implementation to clinic? #RheumNow https://t.co/jLcAtD7FaY https://t.co/YmLwmVWp6k
Md Yuzaiful Md Yusof
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#ACR21 #Abstr0261 In stable Non sJIA, is it safe to taper or stop MTX? Of 375 pts in CARRA registry, 24% tapered and 14% stopped MTX. No diff in flare rates btw those continued vs tapered/stopped. Sustained remission was in ⬆️tapered vs stopped @RheumNow https://t.co/Mm1yfzRBQz https://t.co/rkHvXWj2oO
Md Yuzaiful Md Yusof
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The #Lupus Faculty @RheumNow is proud to share our latest video about learning points from a jam-packed day at #ACR21 https://t.co/LRyuYyHlhi @KDAO2011 @Janetbirdope @bella_mehta @_Castillo_Pedro
Leonard Calabrese
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#ACR21 Ignaki Sanz makes the case that +++ AUTOANTIBODIES are integrally involved in #COVID19 immunopathogeneisis and may rise and fall w disease states- TBD what role they play in acute disease and #LongCovid @CCalabreseDO @VirusesImmunity @CleClinicMD #COVID19AB https://t.co/9dzCSh5V7R
TheDaoIndex
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"The time for young people is now! You are not the future, you are the present; you can make a difference. You may be scared, but take the opportunities and be purposeful." -Dr. A Alakija on the role of young rheumatologists in global health disparities
#ACR21 @ACRheum @yodifiji
TheDaoIndex
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Dr. Marvisi presented a case: refractory MPA relapsed w/prednisone < 25 mg/day. Genetic studies c/w VEXAS. Is MPA/vasculitis part of VEXAS? The experts say: Maybe- VEXAS is such a new entity, there may be a common pathway (e.g NFkB affected by ubiquination, IL-6 role) #ACR21 https://t.co/kEOsruJ8DE
TheDaoIndex
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She was considered a "high risk hire" b/c of her accent, being young, and being a mother of 3 children who still needs her. -Dr. Graciela Alarcon, a giant in rheumatology,talked about her life in the Global Women Leaders in Rheumatology #ACR21 @ACRheum @rheumnow #strongwomen https://t.co/Oxmy8ruIZF
TheDaoIndex
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Solutions to the Gender Gap:
👉treat gender equality as an innovation challenge requiring innovative solutions
👉create culture where people feel personally responsible for change (not coerced)
👉implement action plans to support behavioral changes with measurable targets
#ACR21 https://t.co/BrExrHx1S7
TheDaoIndex
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My typo: * patience (but "patients" are needed too for a rheum career)
