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Biosimilars for Rheum Disease: Failure to Launch

d RheumNow

The availability of biologic biosimilars has thus far had negligible impact on prescribing practices in the United States, in stark contrast to what has been observed in some European countries, researchers reported.

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QD Clinic - Dealing with Non-adherence

d Jack Cush, MD

QD Clinic - Lessons from the clinic. Today’s clinic topic: Dealing with Non-Adherence in the Clinic.

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Steroid-Sparing Effect of Tocilizumab in Refractory Takayasu Arteritis

d Jack Cush, MD

A controlled clinical trial has shown that giving the IL-6 receptor antibody, tocilizumab (TCZ), to  patients with Takayasu arteritis (TAK) results in clinical efficacy and has a steroid sparing efffect.

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CDC: 15% of US Adults are Physically Inactive

d Jack Cush, MD

All states and territories had more than 15% of adults who were physically inactive and this estimate ranged from 17.3 to 47.7%,  according to new state maps of adult physical inactivity prevalence released today by the Centers for Disease Control and Prevention (CDC).

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RheumNow Podcast- The Down Side of Steroids (1.17.20)

d Jack Cush, MD

Dr. Jack Cush reviews the journal reports and news from RheumNow.com.
Be sure to register for RheumNow Live 3/13/2020 in Fort Worth
Rheumnow.live.

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Hydroxychloroquine in RA metanalysis shows clinical efficacy of HCQ was similar to or lower than MTX or SSZ monotherapy. When HCQ combined with other DMARDs it increased the clinical efficacy. There is a paucity of data on HCQ structural (Xray) benefits https://t.co/Q5ukHrjybJ

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Dr. John Cush RheumNow ( View Tweet)

A of TB risk with TNF inhib - Risks by country: - Worldwide - 9.62 cases/1000 pts exposed - Asia, 13.47 /1000 - S America 11.75 /1000 - Europe, 6.28 /1000 patients - North America 4.34 /1000 (low risk (USA, EU) and high risk countries (Asia, S.Amer). https://t.co/MNtnjbEuMS

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Dr. John Cush RheumNow ( View Tweet)

Anti-transcription intermediary factor 1 (TIF1)-γ autoantibodies are linked with cancer-associated Dermatomyositis in adults https://t.co/DeBoDdEbV1

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Dr. John Cush RheumNow ( View Tweet)

#MLK - “The ultimate measure of a man is not where he stands in moments of comfort and convenience, but where he stands at times of challenge and controversy.” - Martin Luther King, Jr.

Dr. John Cush RheumNow ( View Tweet)

#MLK - “If you can’t fly then run, if you can’t run then walk, if you can’t walk then crawl, but whatever you do you have to keep moving forward.” - Martin Luther King Jr.

Dr. John Cush RheumNow ( View Tweet)

#MLK "Everybody can be great … because anybody can serve. You don’t have to have a college degree to serve. You don’t have to make your subject and verb agree to serve. You only need a heart full of grace. A soul generated by love.” - Martin Luther King

Dr. John Cush RheumNow ( View Tweet)

The driving force behind @RheumNow profiled in this article. Thanks for taking the time Jack https://t.co/T4nWMLDYFL

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Dr Irwin Lim _connectedcare ( View Tweet)

RheumNow Podcast is up! S ame day hip replacments? Steroids & organ damage; Watch it here>> https://t.co/QY3qxTEYv0 or listen to the podcast in your car on Android Auto, Apple car play or https://t.co/3aCQ6qEJPx

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Dr. John Cush RheumNow ( View Tweet)

The future is bedside-to-bench: "Systemic comparison (of immunotherapy irAEs) with canonical forms of (inflamm arthritis)... may shed novel insights into the development of IA more broadly and identify common mechanisms and targets for therapy" @cappelliMD https://t.co/zYZyUFx8KU

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David Liew drdavidliew ( View Tweet)

Thanks to Irwin and Rheuma Republic for this generous bio and profile of yours truly. RheumNow gives me a daily chance to spread the wealth or to get it right! https://t.co/gvQf5sUF3m

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Dr. John Cush RheumNow ( View Tweet)

Attending the annual ASAS meeting in Houston and hearing about the development of new platforms to disseminate information on #spondyloarthritis #axialspondyloarthritis https://t.co/uqDxbkHX7N

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Dr. Antoni Chan synovialjoints ( View Tweet)

The RheumNow Podcast is up! Steroids and organ damage; same day hip replacments? Tulips and d-Dimers. Watch in on RheumNow>> https://t.co/QY3qxTEYv0 or listen to the podcast in your car on Android Auto, Apple car play or https://t.co/3aCQ6qEJPx

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Dr. John Cush RheumNow ( View Tweet)

23% of RA patients have moderate-to-severe Obstructive Sleep Apnea (AHI ≥ 15) - study of RA patients 199 patients underwent PSG, OSA is more common in RA than in the general population, but there is no relationship with disease activity. https://t.co/noojvYmtMk

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Dr. John Cush RheumNow ( View Tweet)

Analysis of worldwide data on Abatacept shows that compared with other bDMARDs, ABA was not associated with an increased overall cancer risk [ROR 0.98 (95% CI 0.91, 1.05)], but may be increased for risk of melanoma [1.58 (95% CI 1.17, 2.08)] https://t.co/3EI52M5kIR

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Dr. John Cush RheumNow ( View Tweet)

Actress Tatum O'Neal, 56, was diagnosed with rheumatoid arthritis at age 50, but had symptoms for almost 10 years. https://t.co/DotJHTLU3h

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Dr. John Cush RheumNow ( View Tweet)

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