All News
Study compared 491SLE pts tested for ANCA Abs w/ 171 ANCA-associated vasculitis (AAV) pts. 46 SLE pts were ANCA+. ANCA-positive LN have worse baseline renal function and lower protein remission rates . https://t.co/jlikQlW9OR https://t.co/yMcULGsnTu
Sep 24, 2023
Ginger may reduce Netosis, AutoAb & thrombosis in SLE. 6-gingerol is the most bioactive component of ginger root. 6-gingerol attenuates neutrophil extracellular trap release in murine models & partially dependenet on phosphodiesterase inhibition. https://t.co/urlmWFmdSl https://t.co/aRIOZcgSub
Sep 22, 2023
Single center study of 401 systemic sclerosis pts finds 10% who meet SLE criteria. SSc-SLE overlap pts were more likely to be female, African American, w/ limited skin SSc, +U1RNP (rare CNS/renal involvement), & similar mortality to SSc alone. https://t.co/KXcbS5OfKh https://t.co/kEwBt8hDWg
Sep 18, 2023
Hydroxychloroquine Adherence Lowers Cardiovascular Risks
A new study shows that adherence to the antimalarial agent significantly lowers future risk of cardiovascular events in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) patients.
https://t.co/XzXcBP7XoO https://t.co/V2EQJ2GlpC
Sep 16, 2023
Multinational study of 3002 #SLE pts who were in LDAS or remission.Tapering of steroids or immunosuppressants was associated with higher odds of flare (vs continuing) (OR 1·24; 1·10–1·39]; p=0·0005). Remissioni/LLDAS >6mos assoc w/ less flare risk https://t.co/NOvQnlPTNp https://t.co/WRBtQeraux
Sep 13, 2023
Hydroxychloroquine Adherence Lowers Cardiovascular Risks
Sep 11, 2023
Daily hydroxychloroquine (HCQ) is better than an apple a day; as a new study shows that adherence to the antimalarial agent significantly lowers future risk of cardiovascular events in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) patients.
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SAVE THE DATE! RheumNow Live will now be taking place in January!
Who is joining us? https://t.co/EdrLp87Z81
Sep 09, 2023
RheumNow Podcast – with Special Guest Dr. Janet Pope (9.8.2023)
Sep 08, 2023
This week, Dr. Jack Cush reviews the news with special guest, Dr. Janet Pope. They discuss "Not-non-Inferior", large scale genetic screening, Zoster risk w/ newer lupus drugs, tapering, RA referral problems and the TNR webinar session on "ORAL Surveillance Revisited".
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HCQ levels & SLE disease activity was measured at 158 baseline SLE pt-visits, 19% had active lupus. Whole blood HCQ levels within 750-1200 ng/ml range was assoc w/ 71% lower odds of active lupus(adj OR 0.29). https://t.co/hszzCBjGxR https://t.co/bKytl6hyMr
Sep 07, 2023
Editorial
Prognostic Stratification of Lupus Nephritis: The Importance of Renal Histology
📰 https://t.co/o3e0gWQ7sj
#histopathology #kidneyfailure #lupusnephritis #lupus https://t.co/Cu038ZtqiH
Sep 05, 2023
Anifrolumab targets type I IFN pathway. In #SLE Trials, pts on ANIF had as much as 8-fold higher rate of Herpes zoster. HZ incidence is 6.9 vs 1.5/100 PYs on ANIF vs PBO. Other drugs may affect IFN - sifalimumab litifilimab, daxdilimab, deucravacitinib https://t.co/V6BceVjRDc https://t.co/lcjbjS9uZt
Sep 04, 2023
Hard Decisions in RA (9.1.2023)
Sep 01, 2023
Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow, and introduces our September campaign - "Hard Decisions in RA".
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SAVE THE DATE! RheumNow Live will now be taking place in January!
Will you be there? https://t.co/WCfBzthXvl
Aug 31, 2023
Lupus study from N. Zealand (2005–2021) shows #SLE pts had 4x worse survival compared to gen. population. From 2,802 pts 25% died, w/ 30% being SLE deaths. SMR=0.29/100K in women (0.05 men). Younger more likely to die from SLE; 2X worse in Māori https://t.co/6fhoehLu71 https://t.co/2JrKsHDyfW
Aug 30, 2023
2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria
Aug 29, 2023
The American College of Rheumatology (ACR) and EULAR have combined efforts to establish an international multidisciplinary Steering Committee to develop classification criteria for the new antiphospholipid syndrome (APS) to be applied in observational studies and clinical trials.
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We are excited to share our exclusive interview with Dr. Don Thomas, a clinical rheumatologist and author of the best-selling book, The Lupus Encyclopedia!
View this interview on our YouTube channel by following this link: https://t.co/D8yAQMt8CX https://t.co/yuJDlJEETf
Aug 29, 2023
Before COVID, we never worried about the heart from hydroxychloroquine (except very rare cardiomyopathy). This study (Einstein #Lupus cohort) confirms positive benefits with nonsmokers having reduced HFrEF, arrhythmia, and cardiac deaths from 2005-2021; HCQ did NOT increase heart… https://t.co/l1Q2MqDMuX
Aug 27, 2023
Livedo reticularis is a painless, cyanotic cutaneous mottling in a fishnet pattern, often on extremities > trunk & exaggerated by cold. NOT specific but may be assoc w/ fibromyalgia, Raynauds, atheromatous or autoimmune Dz, hyperviscosity, thrombotic Dz https://t.co/DNec96Wf2x https://t.co/7HOjwuFQm9
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Aug 22, 2023
Retro cohort study finds COVID may incr risk of autoimmunity & risk is decr by Vax. Found Incr rates of SpA(1.32), RA (1.29), PsO(1.42), Graves' (1.30), APL (2.12), ITP (2.1), MS (2.66), vasculitis (1.46). Vax decr pemphigoid, Graves, APL, ITP, SLE https://t.co/Ln3NN6RfmZ https://t.co/VH3cia4AXr
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Aug 21, 2023
Retrospective cohort study (2009-2022) found that #SLE is a risk factor for myelodysplastic syndrome (MDS) among RMD pts. Found 64 MDS in 55 841 PYs F/U (1.15/1000 PY). SLE was risk factor for MDS (adj HR 2.61). Lower Hgb could be an early clue! https://t.co/z8tXqSGiFz https://t.co/HJ8SLjOSzM
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Aug 21, 2023