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Fallen Angels (1.17.2025)
Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com; and pays homage to colleagues who passed away in 2024.
Read ArticleChildhood Maltreatment and the Risk of Rheumatic Diseases
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EurekAlert!
A UK retrospective matched open cohort study shows that children who suffered frmo abuse, neglect or domestic abuse carry a significantly increased risk of developing rheumatoid arthritis or psoriasis in later life.
Read ArticleOutcomes of Multisystem Inflammatory Syndrome in Children (MIS-C)
A nationwide cohort study of patients with multisystem inflammatory syndrome in children (MIS-C), a life-threatening complication of COVID-19 infection, showed that many had severe disease during the acute phase, but most recovered quickly and had a reassuring midterm prognosis.
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Childhood Maltreatment and the Risk of Rheumatic Diseases
A UK retrospective matched open cohort study shows that children who suffered from abuse, neglect or domestic abuse carry a significantly increased risk of developing rheumatoid arthritis or psoriasis in later life.… https://t.co/f0XMDJbvvg https://t.co/9KvpixsNFL
Dr. John Cush RheumNow ( View Tweet)
Outcomes of Multisystem Inflammatory Syndrome in Children (MIS-C)
A nationwide cohort study of patients with MIS-C, a life-threatening complication of COVID-19 infection, showed that many had severe disease during the acute phase, but most recovered quickly and had a reassuring… https://t.co/qbV4Z8SX0x https://t.co/VUD5KHeXZH
Dr. John Cush RheumNow ( View Tweet)
Challenging the status quo is difficult, and worth it. Happy Birthday.
-Seth Godin https://t.co/xVgdC8wJnD https://t.co/Mdtm9XwOs9
Links:
Dr. John Cush RheumNow ( View Tweet)
U.S. overdose deaths far outpace other countries. In 2023 US drug overdoses >100,000 for 3rd year — a >50% jump since 2019. 2022 rate=324/1 million. High rates attributed to fentanyl, polysubstance use, counterfeit pills, variance in state policies on harm reduction… https://t.co/IYpytkEgpt https://t.co/HrrU9SCJT1
Dr. John Cush RheumNow ( View Tweet)
🔍 Vaccine immunogenicity with JAKi treatment
Watch Dr. Kevin Winthrop present long-term immunogenicity of an adjuvant recombinant zoster vaccine in patients aged ≥50 years with RA receiving a JAKi. Sponsored by AbbVie Medical Affairs + Health Impact.
https://t.co/bDGygnXXcP https://t.co/aIklRFJMHt
Dr. John Cush RheumNow ( View Tweet)
GLP-1 Agonists Alleviate Knee Osteoarthritis
In October, the NEJM published a randomized clinical trial demonstrating the efficacy of glucagon-like peptide-1 receptor agonists (GLP-1ra) in patients with obesity and knee osteoarthritis.
https://t.co/jlYGDTTsYZ https://t.co/O23mN1CPVO
Dr. John Cush RheumNow ( View Tweet)
QD Clinic - CREST or More?
Is this CREST or Diffuse PSS?
Features Dr. Jack Cush.
QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025
Register at https://t.co/2dcFVgu8z6
https://t.co/h7e2tcOaaF https://t.co/6AceRXb4Nq
Dr. John Cush RheumNow ( View Tweet)
Screening for Osteoporosis to Prevent Fractures - USPSTF Recommendations
The US Preventive Services Task Force (USPSTF) has done a systematic review on osteoporosis screening to prevent fractures and put forth its recent recommendations. These recommendations pertain to adults… https://t.co/u8LsIf453d https://t.co/I5DsQkkV2X
Dr. John Cush RheumNow ( View Tweet)
Among SLE pts, males have a higher risk of infection compared to females. Males have a (6X) higher prevalence of pneumonia and women have more urinary tract infections. Retrospective study of 119 SLE pts (107 females, 12 males) https://t.co/dhq3yoFUi8 https://t.co/Lf1X2k0Gte
Dr. John Cush RheumNow ( View Tweet)
Dazukibart Effective in Adults with Dermatomyositis
Lancet reports that the use of dazukibart, a selective monoclonal antibody against interferon B (IFNβ), was clinically effective in reducing disease activity in adults with active dermatomyositis (DM).… https://t.co/7oRyxrFpar https://t.co/wA06Kzsdqg
Dr. John Cush RheumNow ( View Tweet)
Just published, a new review of Axial spondyloarthritis from Baraliakos, et al in Lancet! https://t.co/0pIFM1Q2jO https://t.co/iGQ3ES7Nie
Links:
Dr. John Cush RheumNow ( View Tweet)
Network metanalysis of 9 RCTs, 3699 patients looked at small molecule Rx in #PsA. With ACR 50/70, PASI 75, & HAQ-DI @ wk 12-16, UPA was > ADA in PASI75 (RR 1.2); Deucravacitinib > Otezla at HAQ (RR −0.16) no OTHER SIGNIF differences observed https://t.co/WQCFQDnnft https://t.co/7NTNIpzEuG
Dr. John Cush RheumNow ( View Tweet)
QD Clinic - Treating Overlap with ILD
Polyarthritis, ILD, Dermatomyositis - how to treat?
Features Dr. Jack Cush.
QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025
Register at https://t.co/2dcFVgu8z6
https://t.co/CsIpdS8hyd https://t.co/I92p5U3UTp
Dr. John Cush RheumNow ( View Tweet)
Screening for Osteoporosis to Prevent Fractures - USPSTF Recommendations
The US Preventive Services Task Force (USPSTF) has done a systematic review on osteoporosis screening to prevent fractures and put forth its recent recommendations. These recommendations pertain to adults… https://t.co/gQ1vcpxih7 https://t.co/SQLJPALq3f
Dr. John Cush RheumNow ( View Tweet)
BACHELOR Trial - Baricitinib in Early Polymyalgia Rheumatica
Lancet reports a French study demonstrating the efficacy of baricitinib in patients with polymyalgia rheumatica (PMR).
Glucocorticoids are the mainstay of therapy in PMR patients and may be problematic in older… https://t.co/svLmE6OBWm https://t.co/K8sdROswxV
Dr. John Cush RheumNow ( View Tweet)
CDC/ACIP 2025 new Immunization recommendations w/ new vaccine recs for COVID-19, influenza, meningococcal serogroup B, pneumococcal, & RSV. Influenza vaccines have been changed from the quadrivalent to trivalent formulations. https://t.co/Kh1NXMuhVU https://t.co/CRq87PZ31j
Dr. John Cush RheumNow ( View Tweet)
QD Clinic - Acute Neck & Back Pain
Acute onset febrile, polyarthritis, neck and low back pain
Features Dr. Jack Cush.
QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025
Register at https://t.co/2dcFVgu8z6
https://t.co/2GqyqXAjbF https://t.co/vIeqdHyayV
Dr. John Cush RheumNow ( View Tweet)