All News
In GCA, Hospital Admission Is Bad News
1/3 of patients admitted w/ GCA were rehospitalized within 6 months, largely because of complications potentially related to corticosteroid therapy, researchers found in a retrospective cohort study.
https://t.co/zaWZn7F9sl https://t.co/OfuyZxNbaa
Links:
Dr. John Cush RheumNow ( View Tweet)
Join us for RheumNow Live this March 18-19 in Dallas, TX! We're not like other meetings--we're answering the questions you want answered.
RNL is a meeting to engage your mind and change your practice. Join us in-person or virtually!
https://t.co/bMphD12Bie https://t.co/Hx0uHAIUWd
Links:
Dr. John Cush RheumNow ( View Tweet)
Extreme Global Costs of Physical Inactivity
A global, population-based study shows that physical inactivity is not only an important modifiable risk factor for NCDs and mental health conditions, it also imparts a considerable health and economic burden.
https… https://t.co/eZEW6LGpiL
Dr. John Cush RheumNow ( View Tweet)
Medical (AKA surgical) masks are not inferior to N95 fitted masks. A study of 1009 medical workers in 4 countries caring for COVID+ infected patients shows equal rate of PCR+ COVID tests (10.5% vs 9.3% +) (HR 1.14 [95% CI, 0.77 to 1.69]) https://t.co/wTuLHcOxlO https://t.co/gjqfLOU7JW
Links:
Dr. John Cush RheumNow ( View Tweet)
INBUILD Study of 170 pts with autoimmune related ILD showed nintedanib signifi. slowed the rate of FVC decline in FVC decline over 52 wks (NIN -75.9 mL/yr vs PBO -178.6 mL/yr). AE's (mostly diarrhea) leading to D/C was NIN 17.1% vs PBO 10.2% https://t.co/CmbF5NQMfJ #BestOf2022
Links:
Dr. John Cush RheumNow ( View Tweet)
AVOID THE WEEKEND! Study of high-impact rheumatology journals (Rheumatology, J Rheum, & Seminars A&R) shows higher risk of "desk rejections" by editor (avoiding peer review) for manuscripts submitted Saturday (OR 1.23) or Sunday (OR 1.13) https://t.co/rWIkiYgh8Y https://t.co/kPSJmfWSUl
Links:
Dr. John Cush RheumNow ( View Tweet)
Good review of Diagnosis and Treatment of Pulmonary Sarcoidosis in JAMA.
- Lung progression (in only 10%) assoc w/ 12-18% 5yr mortality
- Sx Sarcoid w/ Lung: start Pred 20 to 40 mg/d for 2 -6 wks
- Steroid sparing w/ MTX, AZA or TNFi
https://t.co/aVnUXaj0sj https://t.co/JN142hlR6g
Links:
Dr. John Cush RheumNow ( View Tweet)
Full read review of advances in bone biology leading to drug development (denosumab, romosuzumab, Burosumab), advances in Pagets and rickets and key regulatory molecules for bone remodeling, RANK, RANKL, OPG, & sclerostin https://t.co/1d6A6MsdbJ https://t.co/IuKEp1PQtr
Links:
Dr. John Cush RheumNow ( View Tweet)
JAMA - Update/Review of Hemochromatosis Dx and Rx.
- 5 gene defects in hepcidin. 95% HFE & the C282Y variant
- 90% are asymptomatic
- Suspicion w/ arthralgias, LFTs, hepatomegaly, cardiomyopathy, 1st degr relative
- Untreated, 9% risk of cirrhosis
https://t.co/LWbIbLITK9 https://t.co/xDpA16K0tm
Links:
Dr. John Cush RheumNow ( View Tweet)
#POTS
Postural orthostatic tachycardia syndrome - how it might link to other conditions
https://t.co/Ekn6KtOrC4
#Fibromyalgia #chronicillness #migraine #hypermobility #EDS https://t.co/JX1WDm2KKn
Dr Gurdeep Dulay gurdeep_dulay ( View Tweet)
$520 billion is the estimated cost of physical inactivity from 2020 to 2030 @LancetGH: https://t.co/JynmtU9oCF
Of the expected 500 million preventable cases of disease, 43% due to #depression and #anxiety.
#MentalHealthMatters @fiona_bull https://t.co/sVjkceNGiq
Scott Lear, PhD DrScottLear ( View Tweet)
Poncet’s disease: a reactive arthritis secondary to pulmonary M. tuberculosis
https://t.co/qMorRZBbi8
Links:
Dr. John Cush RheumNow ( View Tweet)
COPA, a rare syndrome w polyarthritis, ILD, pulmonary hemorrhage, w excessive STING signaling. #RWCS2022
@RWCSmtg https://t.co/EUv8sMK8dx
Dr. John Cush RheumNow ( View Tweet)
New Hope for Hand Osteoarthritis
The drug talarozole – which increases retinoic acid – could be a promising new treatment for hand osteoarthritis.
https://t.co/jVMLiJLnch https://t.co/0nk8WA2k1S
Links:
Dr. John Cush RheumNow ( View Tweet)
Lit review of MDA5 antibody-positive clinically amyopathic dermatomyositis w/ ILD - shows limited data from 15 studies, 388 pts, 1 RCT: ? best survival with high-dose steroids + immunosuppressive (CTX or CyA/tacrolimus). Refractory dz Rx w/PLEX, Tofa, RTX https://t.co/8yE4B3SfRg
Links:
Dr. John Cush RheumNow ( View Tweet)
Lumbar spinal stenosis affects 103 million worldwide (11% of older adults in US). 1st line Rx is activity modification, analgesia, PT. Benefits of epidural steroids havent been established. Decompressive surgery only for selected pts w/ pain & limitation https://t.co/zye3p5j2Hn https://t.co/HzVGLT8Qgl
Links:
Dr. John Cush RheumNow ( View Tweet)
Cancer Risk with Scleroderma
Spanish Scleroderma Registry examined a large cohort of systemic sclerosis (SSc) patients showing an increased cancer risk, especially breast, lung, hematologic and colorectal cancer.
https://t.co/S3EHajMF9q
#BestOf2022 https://t.co/kV772Jef4V
Links:
Dr. John Cush RheumNow ( View Tweet)
#BestOf2022
Metanalysis of 7 studies shows that oral anticoagulants need not be discontinued for joint injections or aspiration. Only pts w/ hemorrhage after 5427 procedures, over 32-yrs. INR values of 3 bleeding cases was 1.9, 2.3, and 3.4. https://t.co/8e1zIhDTJt https://t.co/L4vIkWf2OL
Links:
Dr. John Cush RheumNow ( View Tweet)
COVID-19 Vaccine Responses in Rheumatic Disease Patients
Nature Reviews Rheumatology features a review of three notable papers that address the impact of SARS-CoV-2 vaccination on people with inflammatory rheumatic disease.
https://t.co/R9UM3amPRR. https://t.co/WmHyVKdsxw
Links:
Dr. John Cush RheumNow ( View Tweet)
Review of the Rheumatic causes of Pericarditis and their management. Causes: SLE, RA, MCTD, Myositis, EGPA, GPA, IgG4-rel Dz, FMF, TRAPS, CAPS, AOSD, JIA, Sarcoidosis, Kawasakis, GCA, Takayasu's https://t.co/MQmkUe4Yey https://t.co/FSfrznoeBe
Dr. John Cush RheumNow ( View Tweet)