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The Annals of Internal Medicine has published a study showing online yoga education and an unsupervised yoga program may improve physical function did not improve knee pain after 12 weeks and 24 weeks.
EMA has approved 86 biosimilar medicines since 2006 and has issued a harmonizing statement for EU countries that biosimi

Dr. John Cush RheumNow

4 years ago
EMA has approved 86 biosimilar medicines since 2006 and has issued a harmonizing statement for EU countries that biosimilars are interchangeable with their reference medicine or with an equivalent biosimilar. https://t.co/ajsP1ulZTQ
RINOMAX Trial studied single dose of 500 mg rituximab IV in myasthenia gravis - 47 MG pts randomized to RTX or PBO, afte

Dr. John Cush RheumNow

4 years ago
RINOMAX Trial studied single dose of 500 mg rituximab IV in myasthenia gravis - 47 MG pts randomized to RTX or PBO, after 4 mos RTX response (71% vs 29%) superior to PBO. Further studies are needed https://t.co/XvAWRH8fUz
Deep Vein Thrombosis reviewed in current Annals of Internal Medicine - VTE is the 3rd most common CVD, seen in 5% of pop

Dr. John Cush RheumNow

4 years ago
Deep Vein Thrombosis reviewed in current Annals of Internal Medicine - VTE is the 3rd most common CVD, seen in 5% of population. Half of VTE assoc w/ transient preventable risk factors. Direct oral anticoagulants are effective and safer https://t.co/6utxivuwf6
Propensity matched pairs (n=237 872) of perioperative pts - gabapentin users and nonusers shows perioperative gabapent

Dr. John Cush RheumNow

4 years ago
Propensity matched pairs (n=237 872) of perioperative pts - gabapentin users and nonusers shows perioperative gabapentin use had significantly more delirium (RR 1.28), antipsychotic Rx (1.17 ) & pneumonia (1.11) vs nonusers post surgery https://t.co/UAZs7Vqy6O
Colchicine vs cimetidine in PFAPA (Periodic fever, aphthous stomatitis, pharyngitis, adenitis) syndrome. 72 pts given C

Dr. John Cush RheumNow

4 years ago

Colchicine vs cimetidine in PFAPA (Periodic fever, aphthous stomatitis, pharyngitis, adenitis) syndrome. 72 pts given COL vs CIM x 3 mos: # of febrile attacks was significantly decreased by both Rx (noninferior to each other) https://t.co/MO7IQ0e8gf

Metals & Hyperuricemia (HU) (20 studies, 63,283 participants): Increased HUA risk arsenic (OR 1.7), calcium (OR 1.

Dr. John Cush RheumNow

4 years ago
Metals & Hyperuricemia (HU) (20 studies, 63,283 participants): Increased HUA risk arsenic (OR 1.7), calcium (OR 1.76), cadmium (OR 1.19), & lead (OR 1.56), BUT lower w/ molybdenum (OR  0.8). No effect w/ Cu, Fe, Mg, Zn, Cd, Co, Al, Hg, Tl https://t.co/xmdBCCBuEk
Burden of OA (knee, hip, hand) for India (1990 - 2019): was 23.5 million in 1990; rose to 62.35 million 2019 (prevalence

Dr. John Cush RheumNow

4 years ago
Burden of OA (knee, hip, hand) for India (1990 - 2019): was 23.5 million in 1990; rose to 62.35 million 2019 (prevalence of 5313 per 100,000). Most common - Knee OA > hand OA > hip OA. The prevalence was higher in females than males. https://t.co/1yMzUulBqk
A cohort study examining hydroxychloroquine dosing in patients with SLE suggests that HCQ doses of 5 mg/kg per day or less, in accordance with current ophthalmology and rheumatology guidelines, was associated with a higher risk of lupus flares, including moderate or severe lupus flares.
New report examines access, affordability, and activity and lifestyle factors in all 50 states and the District of Columbia, evaluating how easy it is to live with a rheumatic disease in your state. No state scored an "A" or "F", and only two states improved their 2018 grades.
Doctor Appointment Wait Times are Up

Forbes reports that a recent Merritt Hawkins survey shows that patients are waitin

Dr. John Cush RheumNow

4 years ago
Doctor Appointment Wait Times are Up Forbes reports that a recent Merritt Hawkins survey shows that patients are waiting an average of 26 days for a scheduled appointment with a doctor. https://t.co/qYfTf2Kxlv https://t.co/BuvihCk0M6
Spanish SpA Registry (REGISPONSER) - 18.3% had psoriasis; w/ 3/4 of these (76%) having PSO before MSK Sxs. Pts w/ PSO be

Dr. John Cush RheumNow

4 years ago
Spanish SpA Registry (REGISPONSER) - 18.3% had psoriasis; w/ 3/4 of these (76%) having PSO before MSK Sxs. Pts w/ PSO before MSK Sxs had shorter dz duration, lower BMI, Less B27 & anterior uveitis, more dactylitis and ^risk PsA dx (78% vs 56%) https://t.co/sz9nKkDoEX https://t.co/B0TmMqZpoY
Does Methotrexate Use Lead to Melanoma?

A systematic review suggests that low-dose methotrexate (MTX) use is associated

Dr. John Cush RheumNow

4 years ago
Does Methotrexate Use Lead to Melanoma? A systematic review suggests that low-dose methotrexate (MTX) use is associated with an increased melanoma risk, but the absolute risk increase could be considered negligible. https://t.co/aLFBoB7M48 https://t.co/A1sHLaguqy
2022 New ACR Guidance on Glucocorticoid-Induced Osteoporosis (GIOP)

The ACR has updated this guideline and includes rec

Dr. John Cush RheumNow

4 years ago
2022 New ACR Guidance on Glucocorticoid-Induced Osteoporosis (GIOP) The ACR has updated this guideline and includes recommendations on abaloparatide (PTHrP) and romosozumab, which are newly available since the ACR’s 2017 GIOP guideline. https://t.co/byehJlihCY https://t.co/xnKPC1V0l7
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