Dr. John Cush RheumNow
4 years 5 months ago
Males respond better than females? Ixekizumab trials in #PSA - 676 pts in Two Phase 3 RCTs - females had lower response rates than males in all measures (ACR20/50/70; MDA; DAPSA) F had ⬆️HAQ, enthesitis, but ⬇️CRP https://t.co/Om8CwbmlgN https://t.co/872E7HGOp2
Pediatric patients with moderate-to-severe plaque psoriasis obtained significant improvement in disease status for as long as 2 years with the interleukin (IL)-17A inhibitor ixekizumab (Taltz), long-term follow-up from a randomized trial showed.
While treat-to-target (T2T) is commonly advocated in gout management, it is unknown if T2T (or more intensive T2T) may result in less bony erosions in gout. Dalbeth et al has studied this is a prospective trial noted that more intensive serum urate lowering is difficult to achieve (orally), carries a high medication burden and does not improve bone erosion scores those with erosive gout.
It’s been reported that approximately one-third to one-half of patients with psoriatic arthritis will try supplements and other complementary and alternative medicinal (CAM) practices without discussing with their rheumatologists. Of those, nearly 90% of PsA patients using CAM report benefits!
Here is your updated review on common supplement data in psoriasis and PsA.
Dr. John Cush RheumNow
4 years 5 months ago
QD Clinic - PsA Lessons from the Clinic
LFT Elevations may be considered differently in PsA patients
QD Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022
https://t.co/dCaWx5OTda https://t.co/bRTVqQ4ZJj
Dr. John Cush RheumNow
4 years 5 months ago
Dr. Laura Coates discusses Precision Medicine in PsA.
https://t.co/ttKHZDGjyC https://t.co/XwahihZyGH
Dr. John Cush RheumNow
4 years 5 months ago
The value of COVID Vaccine after COVID infection - Vax Effx after COVID=445% after 2 doses & 58% after booster during Delta COVID. During Omicron, 35% effect after 2 doses and 68% after a booster dose - best protection conferred by booster https://t.co/VXi70r2nS3 https://t.co/Oeuet3pudD
The Canadian Rheumatology Association’s (CRA) Telehealth Working Group (TWG) has developed a series of best practice statements for the virtual care in adult and pediatric rheumatology patients.
Dr. John Cush RheumNow
4 years 5 months ago
QD Clinic - PsA Lessons from the Clinic
Reasons why PsA patient can lose biologic efficacy and what to do about it
QD Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022
https://t.co/Bxy1G68rU9 https://t.co/CLe9SHfRQJ
Dr. John Cush RheumNow
4 years 5 months ago
Combined Clinics for PsA
Rheums and derms have long worked together in the management of our patients, but the idea of directly collaborating in a single clinic space was novel at the time. Over the years, it has become my favorite clinic of the week.
https://t.co/uY1mZtlvaV https://t.co/5AZ2z2kSVG
Dr. John Cush RheumNow
4 years 5 months ago
Comparison of Tofa, ADA, PBO in OPAL #PSA studies - median time to HAQ response better for Tofa & ADA (30d) vs PBO (>112d), but Tofa had faster Fatigue response (31 vs 90+D). MDA response time same between Tofa v ADA #PSAlways https://t.co/f48Of7bEjN https://t.co/KvfQUbLwCH
Dr. John Cush RheumNow
4 years 5 months ago
NPF COVID-19 report from AAD mtg shows #PSA pts on systemic Rx were not at risk of hospitalization or severe COVID-1 based on US claims data. Also TNFi, IL-17, IL-23 Rx not affect on Vax Ab responses; less hosp (36%) w/ TNFi https://t.co/ekvu0mMvrn https://t.co/Qogm1Vx5hF
Until the publication of the SEAM trial, evidence in the medical literature for the efficacy of the most commonly used drug for psoriatic arthritis worldwide, methotrexate, has been lukewarm at best. Yet we all employ it commonly, either as monotherapy or in combination with biologic or targeted synthetic DMARD treatment. It is inexpensive and widely available, and only modestly toxic.
Dr. John Cush RheumNow
4 years 5 months ago
How long does a good response last to a biologic?
How and When to distinguish between flares and intercurrent illness.
QD Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022
https://t.co/ZIWQysY5dd https://t.co/RZrS6FfUTV

