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RCT showing Midodrine is effective in treating Vasovagal Syncope. 133 pts with hx of median of 6 syncope episodes in th

Dr. John Cush RheumNow

5 years 1 month ago
RCT showing Midodrine is effective in treating Vasovagal Syncope. 133 pts with hx of median of 6 syncope episodes in the prior year; given MID or PBO. After 12 mos, MID had less syncope episodes (42% vs. 61% PBO; RR=0.69) https://t.co/5pCSaYB76m
You know, I'm a very good driver. We all think we're great drivers - but consider what it's like to drive in pain: would you be a good driver? Also, I want you to consider the diagnosis of calcium pyrophosphate dihydrate disease (CPPD). But first, let's look at a study out of Scotland, looking at military service and greater risk of hip and knee replacement.
A psoriatic arthritis (PsA) cohort analysis reveals many similarities and few distinctions between those who present with oligoarticular and polyarticular PsA. A total of 402 PsA patients from the University of Toronto PsA clinic (1978 - 2018) were included. Oligoarthritis was defined by the presence of ≤4 inflamed joints and progression (to polyarticular) as an increase to ≥5 joints. 
The CDC has reported that mRNA vaccine effectiveness against COVID-19–associated hospitalizations was sustained over 24 weeks; but there is evidence of waning protection amongst the immunosuppressed.
https://t.co/wM1iRxtHvk

The interleukin-6 inhibitor, tocilizumab (TCZ), was studied in a cohort of difficult systemic s

Dr. John Cush RheumNow

5 years 1 month ago
https://t.co/wM1iRxtHvk The interleukin-6 inhibitor, tocilizumab (TCZ), was studied in a cohort of difficult systemic sclerosis (SSc) and was shown to be effective in refractory joint and skin disease with good long-term retention rates and disease stabilization. https://t.co/1suUabDGhL
A EULAR task force has promulgated several points to consider in managing difficult-to-treat RA. These "points" are unique in directing the rheumatologist's attention to the potential for misdiagnosis and the impact of comorbid conditions on what is perceived as poorly controlled RA.
Today, public health and medical experts from the U.S. Department of Health and Human Services (HHS) released the following statement on the Administration’s plan for COVID-19 booster shots for the American people.
Free Video from the NEJM - Mobility Assessment in Older Adults. Useful in assessing geriatric patients, frailty, risk o

Dr. John Cush RheumNow

5 years 1 month ago
Free Video from the NEJM - Mobility Assessment in Older Adults. Useful in assessing geriatric patients, frailty, risk of falls (4 stage balance test) and functional impairment. 7:36 long. https://t.co/zZcDDOg12U
Belimumab in Pregnancy? a study of 13 pregnancies in 13 pts, mean age 38 yrs.. There were 11 live births, 1 case omphali

Dr. John Cush RheumNow

5 years 1 month ago
Belimumab in Pregnancy? a study of 13 pregnancies in 13 pts, mean age 38 yrs.. There were 11 live births, 1 case omphalitis (recovered w Abx) . No fetal anomalies found. 6 pts (46%) w/ Hx of recurrent pregnancy loss, four had live births on BEL https://t.co/FJJhepa25M
Acute CPPD arthritis -1697 pts compared w/ 6503 controls. CPPD pts were older (74 yrs), 57% female, 81% White; & ass

Dr. John Cush RheumNow

5 years 1 month ago
Acute CPPD arthritis -1697 pts compared w/ 6503 controls. CPPD pts were older (74 yrs), 57% female, 81% White; & assoc w/ OA (OR 3.1), male (OR 1.3), RA (2.1), gout (2.8), PPI (1.9), diuretics (~1.5). CPPD less likely in Blacks vs Whites (OR 0.47) https://t.co/U22jBmjWXm
#RA & Driving studied w/ installed auto sensor-based instrumentation - 23 controls compared to 33 RA pts (1292 drivi

Dr. John Cush RheumNow

5 years 1 month ago
#RA & Driving studied w/ installed auto sensor-based instrumentation - 23 controls compared to 33 RA pts (1292 driving hrs): shows RA & worsening Dz severity assoc w/ poor vehicle control; Braking/accelerating & steering variability liked to CDAI levels. https://t.co/umXGAbuicz https://t.co/oN2tTXpAtE
Spirometry study in 2,008 #RA patients - compared to controls, RA has a higher risk of restrictive Lung dz (OR 1.36, 95%

Dr. John Cush RheumNow

5 years 1 month ago
Spirometry study in 2,008 #RA patients - compared to controls, RA has a higher risk of restrictive Lung dz (OR 1.36, 95%CI 1.21,1.52) and obstructive LD (OR 1.21, 95%CI 1.07,1.37) independent of confounders like smoking https://t.co/UWViAZL6PO https://t.co/9OBz5ROKhw
The interleukin-6 inhibitor, tocilizumab (TCZ), was studied in a cohort of difficult systemic sclerosis (SSc)  and was shown to be effective in refractory joint and skin disease with good long-term retention rates and disease stabilization.
A new study in Annals of Rheumatic Disease shows that inflammatory arthritis (IA) may impair male fertility, especially during the peak reproductive age when lower fertility rates, higher childlessness rates and more fertility problems were seen.
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