RheumNow Podcast – Driving in Pain (8.20.2021) Save

Dr. Jack Cush reviews the news, journal articles and more from this past week on RheumNow.com.

1. Scottish study of 78 000 veterans shows no association between military service and future OA knee/hip. 78K Vets compared to 253K non-Vets shows Vets with a lower risk of THR (HR 0.87), but not TKR (HR 1.02). https://t.co/JU7Q80qji1
2. Belimumab in Pregnancy? a study of 13 pregnancies in 13 pts, mean age 38 yrs.. There were 11 live births, 1 case omphalitis (recovered w Abx) . No fetal anomalies found. 6 pts (46%) w/ Hx of recurrent pregnancy loss, four had live births on BEL https://t.co/FJJhepa25M
3. Acute CPPD arthritis -1697 pts compared w/ 6503 controls. CPPD pts were older (74 yrs), 57% female, 81% White; & assoc w/ OA (OR 3.1), male (OR 1.3), RA (2.1), gout (2.8), PPI (1.9), diuretics (~1.5). CPPD less likely in Blacks vs Whites (OR 0.47) https://t.co/U22jBmjWXm
4. #RA & Driving studied w/ installed auto sensor-based instrumentation - 23 controls compared to 33 RA pts (1292 driving hrs): shows RA & worsening Dz severity assoc w/ poor vehicle control; Braking/accelerating & steering variability liked to CDAI levels.  https://t.co/umXGAbuicz
5. Oligoarticular Versus Polyarticular Psoriatic Arthritis https://t.co/bIPdfUIL5S
6. Using data from Framingham Study, 347 pt w/ Widespread Pain (WP) compared to 2117 without. WP was associated with an increased risk of all-cause dementia (HR: 1.43), Alzheimer's (HR: 1.47) and stroke risk (HR: 1.29). https://t.co/S1CS01zNkJ
7. 16 Pts on mech ventilation for SARS-CoV-2- induced ARDS with hyperinflammation were treated with ruxolitinib plus standard care - 13/16 survived 28 days. Better outcomes seen w/ RUX and Lymph-neutrophil ration > 0.07.  https://t.co/4O2Y5swE0x
8. Metanalysis of Colchicine in coronary artery disease (CAD) (13RCTs, n=13125), colchicine signif. reduces the risk of MI (OR 0.64) & CVA/TIA (OR 0.50), but has a higher rate of GI upset with no influence on all‐cause mortality (OR 0.96) https://t.co/CRDUFsc6lG
9. Tocilizumab in Refractory Skin and Joint Scleroderma 
10. Booster Shots for Rheumatology Patients on Immunosuppressive Medications
11. HHS, FDA & CDC Joint Recommendation on COVID Booster 
12. EULAR Points on Managing Difficult Rheumatoid Arthritis 
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